Measurement and analysis of physiological parameters in children with bronchial asthma

We have measured electrophysiological parameters of functional state of the central nervous system (CNS) and the visceral nervous system (VNS) with the aim to specify mechanisms of involvement of the latter in the bronch- obstructive syndrome. The electroencephalogram (EEG), the somatosensory evoked potentials (SEPs), the electrocardiogram (ECG) and the pneumogram were recorded in 120 children with bronchial asthma (BA) and in 20 healthy children. The row data were processed with the use of known and the developed new problem-oriented methods. The novel approach was in the analysis of SEPs recorded in different of breathing cycle in comparison with those recorded conventionally. To reduce dimensions of the space of the indicators we have developed adaptive spectral transform, and proposed classification criteria. Our data give evidence of deficiency of the inhibitory processes in the non- specific systems of the brain in children with BA, that allow to search for approaches to development of new therapeutic methods for treatment of this disease.