Monitoring radiofrequency ablation of biological tissue using broadband time-resolved diffuse optical spectroscopy

Research output: Chapter in Book/Report/Conference proceedingsChapterpeer-review

Abstract

Radiofrequency ablation (RFA) is minimally invasive thermotherapy, where a heating source is used to target and kill malignant cells in a tissue. While RFA has tremendous potential in the field of oncology, there is also a need for reliable real-time monitoring of this procedure to avoid over or under treatment. In this work, we investigate the use of time-resolved diffuse optical spectroscopy (DOS) to continuously track the change in optical properties during RFA to monitor the process of ablation. The time evolution of the spectra of the optical properties of the tissue undergoing treatment gives deep insights into the structural and constitutional changes occurring during the RFA treatment.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO_2019
EditorsHamid Dehghani, Heidrun Wabnitz
PublisherOptica Publishing Group (formerly OSA)
ISBN (Electronic)9781510628410
ISBN (Print)9781510628397
DOIs
Publication statusPublished - 2019
Externally publishedYes
EventEuropean Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands
Duration: 23 Jun 201925 Jun 2019

Publication series

NameOptics InfoBase Conference Papers
VolumePart F142-ECBO 2019
ISSN (Electronic)2162-2701

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO_2019
Country/TerritoryNetherlands
CityMunich
Period23/06/1925/06/19

Keywords

  • Absorption
  • Diffuse optical spectroscopy
  • Light scattering
  • Liver
  • Monitoring
  • Non-invasive
  • Radio frequency ablation

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