Multi-parameter on-line cell health monitoring system

E. Moore; A. Paschero; W. Messina; E. McLoughlin

doi:10.1109/ICSENS.2011.6127338

Multi-parameter on-line cell health monitoring system

E. Moore
, A. Paschero
, W. Messina
, E. McLoughlin

University College Cork

Research output: Chapter in Book/Report/Conference proceedings › Conference proceeding › peer-review

Abstract

An integrated cell based biochip microsystem platform that examines the effects of toxic chemicals on cells relevant to human health was developed. The novelty of this platform lies with the integration of mixed sensor technologies with fluidic capability that enables multi-parameter detection, with greater versatility for the end user then what is already currently available. It successfully integrated both optical (imaging) and electrical (impedance, pH, temperature and dissolved oxygen sensors) detection into a platform system with fluidic control. The developed technology uses impedance analysis, which enables accurate, sensitive and reliable assays to be performed in real time and under constant automated monitoring. These types of biosensors offer the potential to study the behaviour of cells in a non-destructive assay format. This technology will have major beneficial implications in research areas such as neurology, cytotoxicity and pharmacology.

Original language	English
Title of host publication	IEEE Sensors 2011 Conference, SENSORS 2011
Pages	320-322
Number of pages	3
DOIs	https://doi.org/10.1109/ICSENS.2011.6127338
Publication status	Published - 2011
Event	10th IEEE SENSORS Conference 2011, SENSORS 2011 - Limerick, Ireland Duration: 28 Oct 2011 → 31 Oct 2011

Publication series

Name	Proceedings of IEEE Sensors

Conference

Conference	10th IEEE SENSORS Conference 2011, SENSORS 2011
Country/Territory	Ireland
City	Limerick
Period	28/10/11 → 31/10/11

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1109/ICSENS.2011.6127338

Cite this

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title = "Multi-parameter on-line cell health monitoring system",

abstract = "An integrated cell based biochip microsystem platform that examines the effects of toxic chemicals on cells relevant to human health was developed. The novelty of this platform lies with the integration of mixed sensor technologies with fluidic capability that enables multi-parameter detection, with greater versatility for the end user then what is already currently available. It successfully integrated both optical (imaging) and electrical (impedance, pH, temperature and dissolved oxygen sensors) detection into a platform system with fluidic control. The developed technology uses impedance analysis, which enables accurate, sensitive and reliable assays to be performed in real time and under constant automated monitoring. These types of biosensors offer the potential to study the behaviour of cells in a non-destructive assay format. This technology will have major beneficial implications in research areas such as neurology, cytotoxicity and pharmacology.",

author = "E. Moore and A. Paschero and W. Messina and E. McLoughlin",

year = "2011",

doi = "10.1109/ICSENS.2011.6127338",

language = "English",

isbn = "9781424492886",

series = "Proceedings of IEEE Sensors",

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note = "10th IEEE SENSORS Conference 2011, SENSORS 2011 ; Conference date: 28-10-2011 Through 31-10-2011",

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T1 - Multi-parameter on-line cell health monitoring system

AU - Moore, E.

AU - Paschero, A.

AU - Messina, W.

AU - McLoughlin, E.

PY - 2011

Y1 - 2011

N2 - An integrated cell based biochip microsystem platform that examines the effects of toxic chemicals on cells relevant to human health was developed. The novelty of this platform lies with the integration of mixed sensor technologies with fluidic capability that enables multi-parameter detection, with greater versatility for the end user then what is already currently available. It successfully integrated both optical (imaging) and electrical (impedance, pH, temperature and dissolved oxygen sensors) detection into a platform system with fluidic control. The developed technology uses impedance analysis, which enables accurate, sensitive and reliable assays to be performed in real time and under constant automated monitoring. These types of biosensors offer the potential to study the behaviour of cells in a non-destructive assay format. This technology will have major beneficial implications in research areas such as neurology, cytotoxicity and pharmacology.

AB - An integrated cell based biochip microsystem platform that examines the effects of toxic chemicals on cells relevant to human health was developed. The novelty of this platform lies with the integration of mixed sensor technologies with fluidic capability that enables multi-parameter detection, with greater versatility for the end user then what is already currently available. It successfully integrated both optical (imaging) and electrical (impedance, pH, temperature and dissolved oxygen sensors) detection into a platform system with fluidic control. The developed technology uses impedance analysis, which enables accurate, sensitive and reliable assays to be performed in real time and under constant automated monitoring. These types of biosensors offer the potential to study the behaviour of cells in a non-destructive assay format. This technology will have major beneficial implications in research areas such as neurology, cytotoxicity and pharmacology.

UR - https://www.scopus.com/pages/publications/84856910939

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DO - 10.1109/ICSENS.2011.6127338

M3 - Conference proceeding

AN - SCOPUS:84856910939

SN - 9781424492886

T3 - Proceedings of IEEE Sensors

SP - 320

EP - 322

BT - IEEE Sensors 2011 Conference, SENSORS 2011

T2 - 10th IEEE SENSORS Conference 2011, SENSORS 2011

Y2 - 28 October 2011 through 31 October 2011

ER -

Multi-parameter on-line cell health monitoring system

Abstract

Publication series

Conference

UN SDGs

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