@inbook{de71f6a12c254e6aa4ad1a6f6946e91d,
title = "Multidistance time domain diffuse optical spectroscopy in the assessment of abdominal fat heterogeneity",
abstract = "A periodic monitoring of the adipose tissue functions due to interventions, such as calorie restriction and bariatric surgery, or pathophysiological processes, has an increasing relevance in clinical diagnostics. Diffuse Optical Spectroscopy (DOS) is a valuable non-invasive tool that can be used in that direction. In this work, we present a pilot study based on Time Domain Broadband Diffuse Optical Spectroscopy (TD DOS) to characterize in vivo the subcutaneous fat tissue in the abdominal region. A first of its kind, portable TD DOS instrumentation, already enrolled in clinical studies, was used. Three healthy male volunteers were considered. Three source-detector separation distances (1, 2, and 3 cm) were used over the broad wavelength range of 600-1100 nm. The analysis was performed using a method based on a heterogeneous model to account for the multi-layered nature of the subcutaneous adipose tissue, and to obtain the optical properties specific to this fat localization. Inter-subject variation of tissue composition data was observed.",
keywords = "Abdomen, absorption, adipose tissue, diffuse optics, fat, heterogeneous, non-invasive, time domain",
author = "P. Lanka and A. Farina and \{Konugolu Venkata Sekar\}, S. and C. Guadagno and L. Spinelli and P. Taroni and R. Cubeddu and E. Nisoli and A. Pifferi",
note = "Publisher Copyright: {\textcopyright} 2018 SPIE.; Biophotonics: Photonic Solutions for Better Health Care VI 2018 ; Conference date: 23-04-2018 Through 26-04-2018",
year = "2018",
doi = "10.1117/12.2307350",
language = "English",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Jurgen Popp and Tuchin, \{Valery V.\} and Pavone, \{Francesco Saverio\}",
booktitle = "Biophotonics",
address = "United States",
}