TY - GEN
T1 - Non-invasive gas monitoring in newborn infants using diode laser absorption spectroscopy
T2 - Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV
AU - Lundin, Patrik
AU - Svanberg, Emilie Krite
AU - Cocola, Lorenzo
AU - Lewander, Märta
AU - Andersson-Engels, Stefan
AU - Jahr, John
AU - Fellman, Vineta
AU - Svanberg, Katarina
AU - Svanberg, Sune
PY - 2012
Y1 - 2012
N2 - Non-invasive diode laser spectroscopy was, for the first time, used to assess gas content in the intestines and the lungs of a new-born, 4 kg, baby. Two gases, water vapor and oxygen, were studied with two low-power tunable diode lasers, illuminating the surface skin tissue and detecting the diffusely emerging light a few centimeters away. The light, having penetrated into the tissue, had experienced absorption by gas located in the lungs and in the intestines. Very distinct water vapor signals were obtained from the intestines while imprint from oxygen was lacking, as expected. Detectable, but minor, signals of water vapor were also obtained from the lungs, illuminating the armpit area and detecting below the collar bone. Water vapor signals were seen but again oxygen signals were lacking, now due to the difficulties of penetration of the oxygen probing light into the lungs of this full-term baby. Ultra-sound images were obtained both from the lungs and from the stomach of the baby. Based on dimensions and our experimental findings, we conclude, that for early pre-term babies, also oxygen should be detectable in the lungs, in addition to intestine and lung detection of water vapor. The present paper focuses on the studies of the intestines while the lung studies will be covered in a forthcoming paper.
AB - Non-invasive diode laser spectroscopy was, for the first time, used to assess gas content in the intestines and the lungs of a new-born, 4 kg, baby. Two gases, water vapor and oxygen, were studied with two low-power tunable diode lasers, illuminating the surface skin tissue and detecting the diffusely emerging light a few centimeters away. The light, having penetrated into the tissue, had experienced absorption by gas located in the lungs and in the intestines. Very distinct water vapor signals were obtained from the intestines while imprint from oxygen was lacking, as expected. Detectable, but minor, signals of water vapor were also obtained from the lungs, illuminating the armpit area and detecting below the collar bone. Water vapor signals were seen but again oxygen signals were lacking, now due to the difficulties of penetration of the oxygen probing light into the lungs of this full-term baby. Ultra-sound images were obtained both from the lungs and from the stomach of the baby. Based on dimensions and our experimental findings, we conclude, that for early pre-term babies, also oxygen should be detectable in the lungs, in addition to intestine and lung detection of water vapor. The present paper focuses on the studies of the intestines while the lung studies will be covered in a forthcoming paper.
KW - Colic
KW - Diode laser
KW - Gastrointestinal tract
KW - Lungs
KW - NEC
KW - Oxygen
KW - Spectroscopy
KW - Surfactant
KW - Water vapor
UR - https://www.scopus.com/pages/publications/84858264239
U2 - 10.1117/12.907464
DO - 10.1117/12.907464
M3 - Conference proceeding
AN - SCOPUS:84858264239
SN - 9780819488725
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optical Diagnostics and Sensing XII
Y2 - 21 January 2012 through 26 January 2012
ER -