TY - GEN
T1 - Non-uniform Fourier transform based rotational alignment in single-particle Cryo-EM
AU - Bai, Zijian
AU - Huang, Jian
N1 - Publisher Copyright:
© 2023 IEEE.
PY - 2023
Y1 - 2023
N2 - In the realm of single-particle Cryo-EM's 2D align-ment problem, conventional practice necessitates interpolation as an intermediate step before applying the Fourier transform to address the in-plane rotation angle. Unfortunately, this interpo-lation process tends to introduce errors, making the process less precise. In contrast, the Non-uniform Fourier transform offers a more direct and accurate mathematical foundation for analyzing and computing the in-plane rotation angle, eliminating the need for interpolation in related problem-solving tasks. Leveraging the capabilities of the Non-uniform Fourier transform, we have developed an algorithm for in-plane rotation angle estimation. To underscore its potential and applicability in the field of single-particle Cryo-EM, we have conducted a direct comparison with the traditional Fourier transform, demonstrating the superior performance of the Non-uniform Fourier transform.
AB - In the realm of single-particle Cryo-EM's 2D align-ment problem, conventional practice necessitates interpolation as an intermediate step before applying the Fourier transform to address the in-plane rotation angle. Unfortunately, this interpo-lation process tends to introduce errors, making the process less precise. In contrast, the Non-uniform Fourier transform offers a more direct and accurate mathematical foundation for analyzing and computing the in-plane rotation angle, eliminating the need for interpolation in related problem-solving tasks. Leveraging the capabilities of the Non-uniform Fourier transform, we have developed an algorithm for in-plane rotation angle estimation. To underscore its potential and applicability in the field of single-particle Cryo-EM, we have conducted a direct comparison with the traditional Fourier transform, demonstrating the superior performance of the Non-uniform Fourier transform.
KW - 2D alignment
KW - in-plane rotation
KW - Non-uniform Fourier transform
KW - single- particle Cryo- Em
UR - https://www.scopus.com/pages/publications/85186110449
U2 - 10.1109/ITAIC58329.2023.10408753
DO - 10.1109/ITAIC58329.2023.10408753
M3 - Conference proceeding
AN - SCOPUS:85186110449
T3 - IEEE Joint International Information Technology and Artificial Intelligence Conference (ITAIC)
SP - 1457
EP - 1463
BT - IEEE ITAIC 2023 - IEEE 11th Joint International Information Technology and Artificial Intelligence Conference
A2 - Xu, Bing
A2 - Mou, Kefen
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 11th Joint International Information Technology and Artificial Intelligence Conference, ITAIC 2023
Y2 - 8 December 2023 through 10 December 2023
ER -