TY - JOUR
T1 - Nonfluoride caries-preventive agents
T2 - Executive summary of evidence-based clinical recommendations
AU - Rethman, Michael P.
AU - Beitrán-Aguilar, Eugenio D.
AU - Billings, Ronald J.
AU - Hujoei, Philippe P.
AU - Katz, Barry P.
AU - Milgrom, Peter
AU - Sohn, Woosung
AU - Stamm, John W.
AU - Gene Watson, Watson
AU - Wolff, Mark
AU - Wright, J. Tim
AU - Zero, Domenick
AU - Krishna Aravamudhan, Aravamudhan
AU - Frantsve-Hawley, Julie
AU - Meyer, Daniel M.
AU - American Dental Association Council on Scientific Affairs Expert Panel on Nonfluoride Caries-Preventive Agents
AU - Whelton, Helen P.
PY - 2011/9
Y1 - 2011/9
N2 - Background: In this article, the authors present evidence-based clinical recommendations regarding the use of nonfluoride caries preventive agents. The recommendations were developed by an expert panel convened by the American Dental Association (ADA) Council on Scientific Affairs. The panel addressed several questions regarding the efficacy of nonfluoride agents in reducing the incidence of caries and arresting or reversing the progression of caries. Types of Studies Reviewed: A panel of experts convened by the ADA Council on Scientific Affairs, in collaboration with ADA Division of Science staff, conducted a MEDLINE search to identify all randomized and nonrandomized clinical studies regarding the use of nonfluoride caries-preventive agents. Results: The panel reviewed evidence from 50 randomized controlled trials and 15 nonrandomized studies to assess the efficacy of various nonfluoride caries-preventive agents. Clinical Implications: The panel concluded that certain nonfluoride agents may provide some benefit as adjunctive therapies in children and adults at higher risk of developing caries. These recommendations are presented as a resource for dentists to consider in the clinical decision-making process. As part of the evidencebased approach to care, these clinical recommendations should be integrated with the practitioner's professional judgment and the patient's needs and preferences.
AB - Background: In this article, the authors present evidence-based clinical recommendations regarding the use of nonfluoride caries preventive agents. The recommendations were developed by an expert panel convened by the American Dental Association (ADA) Council on Scientific Affairs. The panel addressed several questions regarding the efficacy of nonfluoride agents in reducing the incidence of caries and arresting or reversing the progression of caries. Types of Studies Reviewed: A panel of experts convened by the ADA Council on Scientific Affairs, in collaboration with ADA Division of Science staff, conducted a MEDLINE search to identify all randomized and nonrandomized clinical studies regarding the use of nonfluoride caries-preventive agents. Results: The panel reviewed evidence from 50 randomized controlled trials and 15 nonrandomized studies to assess the efficacy of various nonfluoride caries-preventive agents. Clinical Implications: The panel concluded that certain nonfluoride agents may provide some benefit as adjunctive therapies in children and adults at higher risk of developing caries. These recommendations are presented as a resource for dentists to consider in the clinical decision-making process. As part of the evidencebased approach to care, these clinical recommendations should be integrated with the practitioner's professional judgment and the patient's needs and preferences.
KW - Acidulated phosphate fluoride
KW - Caries
KW - Chlorhexidine
KW - Clinical recommendations
KW - Evidence-based dentistry
KW - Xylitol
UR - https://www.scopus.com/pages/publications/80053413077
U2 - 10.14219/jada.archive.2011.0329
DO - 10.14219/jada.archive.2011.0329
M3 - Article
AN - SCOPUS:80053413077
SN - 0002-8177
VL - 142
SP - 1065
EP - 1071
JO - Journal of the American Dental Association
JF - Journal of the American Dental Association
IS - 9
ER -