Novel Surface Modified Polymer Microneedle based Biosensors for Interstitial Fluid Glucose Detection

Research output: Chapter in Book/Report/Conference proceedingsChapterpeer-review

Abstract

Fabrication and characterization of polymer microneedle arrays, compatible with in-vivo glucose sensing, is described. The process generates a polymer microneedle electrode array comprised of an on-chip working, counter and reference electrodes. Glucose oxidase was entrapped in an o-phenylenediamine/ sulphonated-β-cyclodextrin polymer matrix at working electrodes The sensor array demonstrated glucose detection over the range of 0.5 - 19.5 mM. An interference study and a preliminary cytotoxicity study were carried to assess the sensors potential for future use in interstitial fluid.

Original languageEnglish
Title of host publication2019 IEEE Sensors, SENSORS 2019 - Conference Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781728116341
DOIs
Publication statusPublished - Oct 2019
Event18th IEEE Sensors, SENSORS 2019 - Montreal, Canada
Duration: 27 Oct 201930 Oct 2019

Publication series

NameProceedings of IEEE Sensors
Volume2019-October
ISSN (Print)1930-0395
ISSN (Electronic)2168-9229

Conference

Conference18th IEEE Sensors, SENSORS 2019
Country/TerritoryCanada
CityMontreal
Period27/10/1930/10/19

Keywords

  • cytotoxicity analysis
  • glucose sensing
  • Interstitial fluid
  • microneedles
  • pain-free polymer replication

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