Optical Coherence Tomography in Clinical Examination ofNonPigmented Skin Malignancies

  • Laura K. Jensen
  • , Lars Thrane
  • , Peter E. Andersen
  • , Andreas Tycho
  • , Finn Pedersen
  • , Stefan Andersson-Engel
  • , Niels Bendsøe
  • , Sune Svanberg
  • , Katarina Svanberg

Research output: Chapter in Book/Report/Conference proceedingsChapterpeer-review

Abstract

Optical coherence tomography (OCT) images of basal cell carcinomas (BCCs) have been acquired using a compact handheld probe with an integrated video camera allowing the OCT images to be correlated to a skin surface image. In general the healthy tissue of the skin has an obvious stratified structure, whereas the cancerous tissue shows a more homogenous structure. Thus it was demonstrated that it is possible to distinguish BCCs from healthy tissue by means of OCT. Furthermore different histological types of BCC were identified. Comparison of OCT images taken prior to and immediately after photodynamic therapy clearly shows the tissue response to the treatment, and indicates local oedema in the treated area.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2003
PublisherOptica Publishing Group (formerly OSA)
Pages160-167
Number of pages8
ISBN (Electronic)0819450111
Publication statusPublished - 2003
Externally publishedYes
EventEuropean Conference on Biomedical Optics, ECBO 2003 - Munich, Germany
Duration: 22 Jun 2003 → …

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO 2003
Country/TerritoryGermany
CityMunich
Period22/06/03 → …

Keywords

  • basal cell carcinoma
  • human skin
  • Optical coherence tomography
  • photodynamic therapy

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