Pathogenesis and prevention of intraventricular hemorrhage

Aisling A. Garvey; Brian H. Walsh; Terrie E. Inder

doi:10.1016/j.semperi.2022.151592

Pathogenesis and prevention of intraventricular hemorrhage

Aisling A. Garvey
, Brian H. Walsh
, Terrie E. Inder

Research output: Contribution to journal › Article › peer-review

Abstract

Despite improvements in the mortality rates of preterm infants, rates of germinal matrix intraventricular hemorrhage (IVH) have remained static with an overall incidence of 25% in infants less than 32 weeks. The importance of the lesion relates primarily to the underlying injury to the developing brain and the associated long-term neurodevelopmental consequences. This clinical-orientated review focuses on the pathogenesis of IVH and discusses the evidence behind proposed prevention strategies.

Original language	English
Article number	151592
Journal	Seminars in Perinatology
Volume	46
Issue number	5
DOIs	https://doi.org/10.1016/j.semperi.2022.151592
Publication status	Published - Aug 2022
Externally published	Yes

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10.1016/j.semperi.2022.151592

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title = "Pathogenesis and prevention of intraventricular hemorrhage",

abstract = "Despite improvements in the mortality rates of preterm infants, rates of germinal matrix intraventricular hemorrhage (IVH) have remained static with an overall incidence of 25\% in infants less than 32 weeks. The importance of the lesion relates primarily to the underlying injury to the developing brain and the associated long-term neurodevelopmental consequences. This clinical-orientated review focuses on the pathogenesis of IVH and discusses the evidence behind proposed prevention strategies.",

author = "Garvey, \{Aisling A.\} and Walsh, \{Brian H.\} and Inder, \{Terrie E.\}",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

year = "2022",

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doi = "10.1016/j.semperi.2022.151592",

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AU - Garvey, Aisling A.

AU - Walsh, Brian H.

AU - Inder, Terrie E.

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N2 - Despite improvements in the mortality rates of preterm infants, rates of germinal matrix intraventricular hemorrhage (IVH) have remained static with an overall incidence of 25% in infants less than 32 weeks. The importance of the lesion relates primarily to the underlying injury to the developing brain and the associated long-term neurodevelopmental consequences. This clinical-orientated review focuses on the pathogenesis of IVH and discusses the evidence behind proposed prevention strategies.

AB - Despite improvements in the mortality rates of preterm infants, rates of germinal matrix intraventricular hemorrhage (IVH) have remained static with an overall incidence of 25% in infants less than 32 weeks. The importance of the lesion relates primarily to the underlying injury to the developing brain and the associated long-term neurodevelopmental consequences. This clinical-orientated review focuses on the pathogenesis of IVH and discusses the evidence behind proposed prevention strategies.

UR - https://www.scopus.com/pages/publications/85128624992

U2 - 10.1016/j.semperi.2022.151592

DO - 10.1016/j.semperi.2022.151592

M3 - Article

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AN - SCOPUS:85128624992

SN - 0146-0005

VL - 46

JO - Seminars in Perinatology

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Pathogenesis and prevention of intraventricular hemorrhage

Abstract

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