Perioperative Anaphylaxis

P. M. Mertes; K. Tajima; M. A. Regnier-Kimmoun; M. Lambert; G. Iohom; R. M. Guéant-Rodriguez; J. M. Malinovsky

doi:10.1016/j.mcna.2010.04.002

Perioperative Anaphylaxis

P. M. Mertes
, K. Tajima
, M. A. Regnier-Kimmoun
, M. Lambert
, G. Iohom
, R. M. Guéant-Rodriguez
, J. M. Malinovsky

School of Medicine

CHU de Nancy
Institut national de la santé et de la recherche médicale
Hôpital d'adultes de Brabois
Centre Hospitalier Universitaire de Reims

Research output: Contribution to journal › Review article › peer-review

Abstract

The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents are most frequently incriminated, followed by latex and antibiotics, although any drug or substance used may be a culprit. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests, specific immunoglobulin E, or basophil activation assays. Treatment consists of rapid volume expansion and epinephrine administration titrated to symptom severity.

Original language	English
Pages (from-to)	761-789
Number of pages	29
Journal	Medical Clinics of North America
Volume	94
Issue number	4
DOIs	https://doi.org/10.1016/j.mcna.2010.04.002
Publication status	Published - Jul 2010

Keywords

Anaphylaxis
Anesthesia
Antibiotics
Epinephrine
Latex
Neuromuscular blocking agent
Skin test
Tryptase

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10.1016/j.mcna.2010.04.002

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title = "Perioperative Anaphylaxis",

abstract = "The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents are most frequently incriminated, followed by latex and antibiotics, although any drug or substance used may be a culprit. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests, specific immunoglobulin E, or basophil activation assays. Treatment consists of rapid volume expansion and epinephrine administration titrated to symptom severity.",

keywords = "Anaphylaxis, Anesthesia, Antibiotics, Epinephrine, Latex, Neuromuscular blocking agent, Skin test, Tryptase",

author = "Mertes, \{P. M.\} and K. Tajima and Regnier-Kimmoun, \{M. A.\} and M. Lambert and G. Iohom and Gu{\'e}ant-Rodriguez, \{R. M.\} and Malinovsky, \{J. M.\}",

year = "2010",

month = jul,

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language = "English",

volume = "94",

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TY - JOUR

T1 - Perioperative Anaphylaxis

AU - Mertes, P. M.

AU - Tajima, K.

AU - Regnier-Kimmoun, M. A.

AU - Lambert, M.

AU - Iohom, G.

AU - Guéant-Rodriguez, R. M.

AU - Malinovsky, J. M.

PY - 2010/7

Y1 - 2010/7

N2 - The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents are most frequently incriminated, followed by latex and antibiotics, although any drug or substance used may be a culprit. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests, specific immunoglobulin E, or basophil activation assays. Treatment consists of rapid volume expansion and epinephrine administration titrated to symptom severity.

AB - The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents are most frequently incriminated, followed by latex and antibiotics, although any drug or substance used may be a culprit. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests, specific immunoglobulin E, or basophil activation assays. Treatment consists of rapid volume expansion and epinephrine administration titrated to symptom severity.

KW - Anaphylaxis

KW - Anesthesia

KW - Antibiotics

KW - Epinephrine

KW - Latex

KW - Neuromuscular blocking agent

KW - Skin test

KW - Tryptase

UR - https://www.scopus.com/pages/publications/77953600571

U2 - 10.1016/j.mcna.2010.04.002

DO - 10.1016/j.mcna.2010.04.002

M3 - Review article

C2 - 20609862

AN - SCOPUS:77953600571

SN - 0025-7125

VL - 94

SP - 761

EP - 789

JO - Medical Clinics of North America

JF - Medical Clinics of North America

IS - 4

ER -

Perioperative Anaphylaxis

Abstract

Keywords

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