Powering up microbiome-microglia interactions

Caoimhe M.K. Lynch; Gerard Clarke; John F. Cryan

doi:10.1016/j.cmet.2021.10.006

Powering up microbiome-microglia interactions

Caoimhe M.K. Lynch
, Gerard Clarke
, John F. Cryan

University College Cork

Research output: Contribution to journal › Article › peer-review

Abstract

Despite extensive evidence implicating the microbiota in regulating the immune system, the precise mechanisms underlying microbial control of microglial maturation remain unclear. In a methodological tour de force, Erny et al. (2021) identify acetate as an essential microbiota-derived molecule driving microglial metabolic pathways and functions during healthy and diseased states.

Original language	English
Pages (from-to)	2097-2099
Number of pages	3
Journal	Cell Metabolism
Volume	33
Issue number	11
DOIs	https://doi.org/10.1016/j.cmet.2021.10.006
Publication status	Published - 2 Nov 2021

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10.1016/j.cmet.2021.10.006

https://hdl.handle.net/10468/12596Licence: CC BY-NC-ND

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title = "Powering up microbiome-microglia interactions",

abstract = "Despite extensive evidence implicating the microbiota in regulating the immune system, the precise mechanisms underlying microbial control of microglial maturation remain unclear. In a methodological tour de force, Erny et al. (2021) identify acetate as an essential microbiota-derived molecule driving microglial metabolic pathways and functions during healthy and diseased states.",

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AU - Clarke, Gerard

AU - Cryan, John F.

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AB - Despite extensive evidence implicating the microbiota in regulating the immune system, the precise mechanisms underlying microbial control of microglial maturation remain unclear. In a methodological tour de force, Erny et al. (2021) identify acetate as an essential microbiota-derived molecule driving microglial metabolic pathways and functions during healthy and diseased states.

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DO - 10.1016/j.cmet.2021.10.006

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JO - Cell Metabolism

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Powering up microbiome-microglia interactions

Abstract

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