TY - GEN
T1 - Prior information in fluorescence molecular tomography based on multispectral fluorescence emission
AU - Axelsson, J.
AU - Svensson, J.
AU - Andersson-Engels, S.
PY - 2007
Y1 - 2007
N2 - Fluorescence molecular tomography (FMT) suffers from inherent ill-posedness due to the vast number of possible solutions to the reconstruction problem. To increase the robustness of such a problem one need prior information. We present here a method for rendering a priori information of the position of a fluorescent inclusion inside turbid media. The method utilizes solely two spectral bands within the fluorescence spectrum emitted from the fluorophore. The method is presented and verified using experimental data from a tissue phantom. The confinement is also used to impose weights onto the voxels before the inversion of the linear set of equations describing the FMT problem.
AB - Fluorescence molecular tomography (FMT) suffers from inherent ill-posedness due to the vast number of possible solutions to the reconstruction problem. To increase the robustness of such a problem one need prior information. We present here a method for rendering a priori information of the position of a fluorescent inclusion inside turbid media. The method utilizes solely two spectral bands within the fluorescence spectrum emitted from the fluorophore. The method is presented and verified using experimental data from a tissue phantom. The confinement is also used to impose weights onto the voxels before the inversion of the linear set of equations describing the FMT problem.
KW - A priori information
KW - Fluorescence molecular tomography
KW - Fluorescence spectroscopy
KW - Reconstruction schemes
UR - https://www.scopus.com/pages/publications/34247329121
U2 - 10.1117/12.699464
DO - 10.1117/12.699464
M3 - Conference proceeding
AN - SCOPUS:34247329121
SN - 081946547X
SN - 9780819465474
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optical Tomography and Spectroscopy of Tissue VII
T2 - Optical Tomography and Spectroscopy of Tissue VII
Y2 - 21 January 2007 through 24 January 2007
ER -