Recent developments in downstream processing based on affinity interactions

J. H.T. Luong; A. L. Nguyen; K. B. Male

doi:10.1016/0167-7799(87)90060-6

Recent developments in downstream processing based on affinity interactions

J. H.T. Luong
, A. L. Nguyen
, K. B. Male

National Research Council of Canada

Research output: Contribution to journal › Review article › peer-review

Abstract

Novel purification processes have been developed, based on the interaction between complementary biomolecules, to circumvent the difficulties encountered by conventional affinity chromatography. Depending upon the procedure used for isolating the ligand-binder complex, the process can be termed affinity cross-flow filtration, affinity partition or affinity precipitation. This review describes the developments and potentials of such purification techniques.

Original language	English
Pages (from-to)	281-286
Number of pages	6
Journal	Trends in Biotechnology
Volume	5
Issue number	10
DOIs	https://doi.org/10.1016/0167-7799(87)90060-6
Publication status	Published - Oct 1987
Externally published	Yes

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10.1016/0167-7799(87)90060-6

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title = "Recent developments in downstream processing based on affinity interactions",

abstract = "Novel purification processes have been developed, based on the interaction between complementary biomolecules, to circumvent the difficulties encountered by conventional affinity chromatography. Depending upon the procedure used for isolating the ligand-binder complex, the process can be termed affinity cross-flow filtration, affinity partition or affinity precipitation. This review describes the developments and potentials of such purification techniques.",

author = "Luong, \{J. H.T.\} and Nguyen, \{A. L.\} and Male, \{K. B.\}",

year = "1987",

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doi = "10.1016/0167-7799(87)90060-6",

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T1 - Recent developments in downstream processing based on affinity interactions

AU - Luong, J. H.T.

AU - Nguyen, A. L.

AU - Male, K. B.

PY - 1987/10

Y1 - 1987/10

N2 - Novel purification processes have been developed, based on the interaction between complementary biomolecules, to circumvent the difficulties encountered by conventional affinity chromatography. Depending upon the procedure used for isolating the ligand-binder complex, the process can be termed affinity cross-flow filtration, affinity partition or affinity precipitation. This review describes the developments and potentials of such purification techniques.

AB - Novel purification processes have been developed, based on the interaction between complementary biomolecules, to circumvent the difficulties encountered by conventional affinity chromatography. Depending upon the procedure used for isolating the ligand-binder complex, the process can be termed affinity cross-flow filtration, affinity partition or affinity precipitation. This review describes the developments and potentials of such purification techniques.

UR - https://www.scopus.com/pages/publications/0023435620

U2 - 10.1016/0167-7799(87)90060-6

DO - 10.1016/0167-7799(87)90060-6

M3 - Review article

AN - SCOPUS:0023435620

SN - 0167-7799

VL - 5

SP - 281

EP - 286

JO - Trends in Biotechnology

JF - Trends in Biotechnology

IS - 10

ER -

Recent developments in downstream processing based on affinity interactions

Abstract

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