Rigorous characterization of time-resolved diffuse spectroscopy systems for measurements of absorption and scattering properties using solid phantoms

  • Johannes Swartling
  • , Antonio Pifferi
  • , Eleonora Giambattistelli
  • , Ekaterine Chikoidze
  • , Alessandro Torricelli
  • , Paola Taroni
  • , Magnus Andersson
  • , Anders Nilsson
  • , Stefan Andersson-Engels

Research output: Contribution to journalArticlepeer-review

Abstract

Two systems for measurements of absorption and scattering properties, based on picosecond-pulse lasers and single-photon counting detection, were characterized using a detailed protocol. The first system utilizes diode lasers at 660, 785, 910 and 974 nm as light sources. The second employs a Ti:sapphire and a mode-locked dye laser to produce tunable pulses in the range 610 - 1000 nm. Using solid tissue phantoms, the systems were rigorously characterized and compared in terms of absolute accuracy of the measured scattering and absorption coefficients, the linearity over the parameter range, the precision with respect to injected light energy, the stability over time, and the reproducibility of the results. The phantoms were made of epoxy resin with TiO as scatterer and black toner powder as absorber.

Original languageEnglish
Pages (from-to)80-87
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5138
DOIs
Publication statusPublished - 2003
Externally publishedYes
EventPhoton Migration and Diffuse-Light Imaging - Munich, Germany
Duration: 22 Jun 200323 Jun 2003

Keywords

  • Diffusion equation
  • Phantoms
  • Photon migration
  • Time-resolved

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