Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling

Justin Mccarthy

doi:10.1074/jbc.m115.679076

Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling

Justin Mccarthy

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Journal of Biological Chemistry
DOIs	https://doi.org/10.1074/jbc.m115.679076
Publication status	Published - 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Ectodomain
Cell biology
Tumor necrosis factor receptor 1
Presenilin
Tumor necrosis factor alpha
Signal transduction
Internalization
Receptor
Amyloid precursor protein secretase
Endocytosis
Cytokine
Intracellular
Chemistry
Biology
Amyloid precursor protein
Biochemistry
Immunology
Alzheimers disease
Medicine
Internal medicine
Disease
Tumor necrosis factor receptor

Access to Document

10.1074/jbc.m115.679076

https://openalex.org/W2237475923Licence: CC BY

Cite this

@article{a3c7d586fd8a412ea42c70607c49b689,

title = "Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling",

keywords = "Ectodomain, Cell biology, Tumor necrosis factor receptor 1, Presenilin, Tumor necrosis factor alpha, Signal transduction, Internalization, Receptor, Amyloid precursor protein secretase, Endocytosis, Cytokine, Intracellular, Chemistry, Biology, Amyloid precursor protein, Biochemistry, Immunology, Alzheimers disease, Medicine, Internal medicine, Disease, Tumor necrosis factor receptor",

author = "Justin Mccarthy",

year = "2016",

doi = "10.1074/jbc.m115.679076",

language = "English",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology Inc.",

}

TY - JOUR

T1 - Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling

AU - Mccarthy, Justin

PY - 2016

Y1 - 2016

KW - Ectodomain

KW - Cell biology

KW - Tumor necrosis factor receptor 1

KW - Presenilin

KW - Tumor necrosis factor alpha

KW - Signal transduction

KW - Internalization

KW - Receptor

KW - Amyloid precursor protein secretase

KW - Endocytosis

KW - Cytokine

KW - Intracellular

KW - Chemistry

KW - Biology

KW - Amyloid precursor protein

KW - Biochemistry

KW - Immunology

KW - Alzheimers disease

KW - Medicine

KW - Internal medicine

KW - Disease

KW - Tumor necrosis factor receptor

U2 - 10.1074/jbc.m115.679076

DO - 10.1074/jbc.m115.679076

M3 - Article

SN - 0021-9258

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

ER -