Selective detection of dopamine using glassy carbon electrode modified by a combined electropolymerized permselective film of polytyramine and polypyrrole-1-propionic acid

  • Lin Zhou
  • , Fengjun Sluing
  • , Mila Pravda
  • , Jeremy D. Glennon
  • , John H.T. Luong

Research output: Contribution to journalArticlepeer-review

Abstract

A sensitive and selective electrochemical method for the determination of dopamine using a combined electro-polymerized permselective film of polytyramine and polypyrrole-1-propionic acid on a glassy carbon (GC) electrode was developed. The formation of a "layer-by-layer" film has allowed for selective detection of dopamine in the presence of 3,4-dihydroxyphenylalanine (L-DOPA), DOPAC, ascorbic acid, uric acid, epinephrine and norepinephrine. The modified electrodes exhibited a detection limit of 100 nM with linearity ranging from 5 × 10-6 to 5 × 10-5 M. No cleaning step was required during the course of repeated measurement.

Original languageEnglish
Pages (from-to)797-803
Number of pages7
JournalElectroanalysis
Volume21
Issue number7
DOIs
Publication statusPublished - Apr 2009

Keywords

  • Dopamine
  • Electropolymerization
  • Glassy carbon electrode
  • Polypyrrole-1-propionic acid
  • Polytyramine

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