Abstract
A sensitive and selective electrochemical method for the determination of dopamine using a combined electro-polymerized permselective film of polytyramine and polypyrrole-1-propionic acid on a glassy carbon (GC) electrode was developed. The formation of a "layer-by-layer" film has allowed for selective detection of dopamine in the presence of 3,4-dihydroxyphenylalanine (L-DOPA), DOPAC, ascorbic acid, uric acid, epinephrine and norepinephrine. The modified electrodes exhibited a detection limit of 100 nM with linearity ranging from 5 × 10-6 to 5 × 10-5 M. No cleaning step was required during the course of repeated measurement.
| Original language | English |
|---|---|
| Pages (from-to) | 797-803 |
| Number of pages | 7 |
| Journal | Electroanalysis |
| Volume | 21 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Apr 2009 |
Keywords
- Dopamine
- Electropolymerization
- Glassy carbon electrode
- Polypyrrole-1-propionic acid
- Polytyramine
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