Sensor system for on-line monitoring of cell cultures

  • Carmen Moldovan
  • , Rodica Iosub
  • , Radu Cornel
  • , Eric Moore
  • , Anna Paschero
  • , Walter Messina
  • , Danilo Demarchi
  • , Cecilia Codreanu
  • , Daniel Necula
  • , Nita Codreanu
  • , Adrian Dinescu
  • , Bogdan Firtat

Research output: Chapter in Book/Report/Conference proceedingsChapterpeer-review

Abstract

The paper is presenting the development of a sensor system dedicated to monitor the environment of eukaryotic cells culture acting as biosensors for toxins detection. The system we are presenting is containing pH, and temperature sensors integrated into microfluidic channels. The sensors have the role to characterize the cells living conditions (temperature and pH) and are monitoring the cell biochip 24h a day providing data acquisition Labview based. The continuous 46h pH monitoring has been performed and the data will be presented. These data are stored for interpretation and decision. The sensors characteristics will be presented. The sensor system for on-line monitoring of cell cultures is designed to ensure that cells are maintained at 37°C and that both the sensing and electrical contacts function and perform under such conditions. The regulation of the temperature at 37°C within the system ensures that on during analysis is maintained a stable environment which will prolong the lifetime of the cells.

Original languageEnglish
Title of host publicationCAS 2009 Proceedings - 2009 International Semiconductor Conference
Pages263-266
Number of pages4
DOIs
Publication statusPublished - 2009
Event2009 International Semiconductor Conference, CAS 2009 - Sinaia, Romania
Duration: 12 Oct 200914 Oct 2009

Publication series

NameProceedings of the International Semiconductor Conference, CAS
Volume1

Conference

Conference2009 International Semiconductor Conference, CAS 2009
Country/TerritoryRomania
CitySinaia
Period12/10/0914/10/09

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