Superconducting Nanowire Detector for Interstitial Null-Separation Time-Domain Diffuse Optical Spectroscopy

  • Vamshi Damagatla
  • , Pranav Lanka
  • , Andrea Farina
  • , Annalisa Brodu
  • , Niels Noordzij
  • , Jessie Qin-Dregely
  • , Antonio Pifferi

Research output: Chapter in Book/Report/Conference proceedingsChapterpeer-review

Abstract

We demonstrate a novel realization of Interstitial fiber, broadband, Time Domain Diffuse Optical Spectroscopy (TD-DOS) in Null Source-Detector separation (NSDS) approach without temporal gating, by using a Superconducting Nanowire single photon detector (SNSPD) for acquisition. We test its feasibility by performing Monte Carlo simulations and comparing the absorption retrieval of the SNSPD with an ideal scenario and a standard Silicon Photomultiplier (SiPM). Consequently, as per the MEDPHOT protocol, we test experimentally, the absorption linearity of the system on tissue-equivalent liquid phantoms, and demonstrate the scattering-independent retrieval of the absorption spectrum of water using Intralipid phantoms in the wavelength range of 600-1100 nm.

Original languageEnglish
Title of host publicationOptical Tomography and Spectroscopy of Tissue XV
EditorsSergio Fantini, Paola Taroni
PublisherSPIE
ISBN (Electronic)9781510658578
DOIs
Publication statusPublished - 2023
EventOptical Tomography and Spectroscopy of Tissue XV 2023 - San Francisco, United States
Duration: 30 Jan 20231 Feb 2023

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12376
ISSN (Print)1605-7422

Conference

ConferenceOptical Tomography and Spectroscopy of Tissue XV 2023
Country/TerritoryUnited States
CitySan Francisco
Period30/01/231/02/23

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