Suspended-core photonic crystal fibers for SERS detection of biomolecules

Aizhan Issatayeva; Siddra Mariyam; Kiang Wei Kho; Stefan Andersson-Engels; Annamaria Cucinotta

doi:10.1088/2040-8986/ada9fe

Suspended-core photonic crystal fibers for SERS detection of biomolecules

Aizhan Issatayeva
, Siddra Mariyam
, Kiang Wei Kho
, Stefan Andersson-Engels
, Annamaria Cucinotta

Research output: Contribution to journal › Article › peer-review

Abstract

Photonic crystal fiber (PCF) can be used as a microfluidic platform for surface-enhanced Raman spectroscopy (SERS)-based measurement of different samples. PCF can provide a long area of interaction for light, metal nanoparticles (NPs), and analytes incorporated into its holes. This paper provides a COMSOL simulation model for suspended-core PCF used to evaluate the SERS intensity depending on the fiber’s geometry and NPs’ coverage density. The simulation is applied to compare three PCFs with varying sizes and lengths. SERS measurements of adenine and DNA validate the simulation outcomes and demonstrate the potential of PCFs for SERS-based detection of diverse samples.

Original language	English
Article number	045301
Journal	Journal of Optics (United Kingdom)
Volume	27
Issue number	4
DOIs	https://doi.org/10.1088/2040-8986/ada9fe
Publication status	Published - 1 Apr 2025

Keywords

miRNAs detection
photonic crystal fibers
SERS

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10.1088/2040-8986/ada9fe

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title = "Suspended-core photonic crystal fibers for SERS detection of biomolecules",

abstract = "Photonic crystal fiber (PCF) can be used as a microfluidic platform for surface-enhanced Raman spectroscopy (SERS)-based measurement of different samples. PCF can provide a long area of interaction for light, metal nanoparticles (NPs), and analytes incorporated into its holes. This paper provides a COMSOL simulation model for suspended-core PCF used to evaluate the SERS intensity depending on the fiber{\textquoteright}s geometry and NPs{\textquoteright} coverage density. The simulation is applied to compare three PCFs with varying sizes and lengths. SERS measurements of adenine and DNA validate the simulation outcomes and demonstrate the potential of PCFs for SERS-based detection of diverse samples.",

keywords = "miRNAs detection, photonic crystal fibers, SERS",

author = "Aizhan Issatayeva and Siddra Mariyam and Kho, \{Kiang Wei\} and Stefan Andersson-Engels and Annamaria Cucinotta",

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doi = "10.1088/2040-8986/ada9fe",

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T1 - Suspended-core photonic crystal fibers for SERS detection of biomolecules

AU - Issatayeva, Aizhan

AU - Mariyam, Siddra

AU - Kho, Kiang Wei

AU - Andersson-Engels, Stefan

AU - Cucinotta, Annamaria

PY - 2025/4/1

Y1 - 2025/4/1

N2 - Photonic crystal fiber (PCF) can be used as a microfluidic platform for surface-enhanced Raman spectroscopy (SERS)-based measurement of different samples. PCF can provide a long area of interaction for light, metal nanoparticles (NPs), and analytes incorporated into its holes. This paper provides a COMSOL simulation model for suspended-core PCF used to evaluate the SERS intensity depending on the fiber’s geometry and NPs’ coverage density. The simulation is applied to compare three PCFs with varying sizes and lengths. SERS measurements of adenine and DNA validate the simulation outcomes and demonstrate the potential of PCFs for SERS-based detection of diverse samples.

AB - Photonic crystal fiber (PCF) can be used as a microfluidic platform for surface-enhanced Raman spectroscopy (SERS)-based measurement of different samples. PCF can provide a long area of interaction for light, metal nanoparticles (NPs), and analytes incorporated into its holes. This paper provides a COMSOL simulation model for suspended-core PCF used to evaluate the SERS intensity depending on the fiber’s geometry and NPs’ coverage density. The simulation is applied to compare three PCFs with varying sizes and lengths. SERS measurements of adenine and DNA validate the simulation outcomes and demonstrate the potential of PCFs for SERS-based detection of diverse samples.

KW - miRNAs detection

KW - photonic crystal fibers

KW - SERS

UR - https://www.scopus.com/pages/publications/85218504404

U2 - 10.1088/2040-8986/ada9fe

DO - 10.1088/2040-8986/ada9fe

M3 - Article

AN - SCOPUS:85218504404

SN - 2040-8978

VL - 27

JO - Journal of Optics (United Kingdom)

JF - Journal of Optics (United Kingdom)

IS - 4

M1 - 045301

ER -

Suspended-core photonic crystal fibers for SERS detection of biomolecules

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