Synthesis and characterization of stigmasterol oxidation products

David A. Foley; Yvonne O'Callaghan; Nora M. O'Brien; Florence O. McCarthy; Anita R. Maguire

doi:10.1021/jf9024745

Synthesis and characterization of stigmasterol oxidation products

David A. Foley
, Yvonne O'Callaghan
, Nora M. O'Brien
, Florence O. McCarthy
, Anita R. Maguire

University College Cork

Research output: Contribution to journal › Article › peer-review

Abstract

The synthesis and structural characterization of a series of oxides of stigmasterol is described providing a valuable series of reference standards for these oxides, analogous to the cholesterol oxidation products (COPs) which have been shown to have detrimental biological effects. Biological evaluation of the oxides of phytosterols is significant in the context of increased dietary use of phytosterols in the drive to reduce cholesterol absorption.

Original language	English
Pages (from-to)	1165-1173
Number of pages	9
Journal	Journal of Agricultural and Food Chemistry
Volume	58
Issue number	2
DOIs	https://doi.org/10.1021/jf9024745
Publication status	Published - 27 Jan 2010

Keywords

Phytosterol oxidation products
Stlgmasterol oxldes

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10.1021/jf9024745

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title = "Synthesis and characterization of stigmasterol oxidation products",

abstract = "The synthesis and structural characterization of a series of oxides of stigmasterol is described providing a valuable series of reference standards for these oxides, analogous to the cholesterol oxidation products (COPs) which have been shown to have detrimental biological effects. Biological evaluation of the oxides of phytosterols is significant in the context of increased dietary use of phytosterols in the drive to reduce cholesterol absorption.",

keywords = "Phytosterol oxidation products, Stlgmasterol oxldes",

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year = "2010",

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language = "English",

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journal = "Journal of Agricultural and Food Chemistry",

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T1 - Synthesis and characterization of stigmasterol oxidation products

AU - Foley, David A.

AU - O'Callaghan, Yvonne

AU - O'Brien, Nora M.

AU - McCarthy, Florence O.

AU - Maguire, Anita R.

PY - 2010/1/27

Y1 - 2010/1/27

N2 - The synthesis and structural characterization of a series of oxides of stigmasterol is described providing a valuable series of reference standards for these oxides, analogous to the cholesterol oxidation products (COPs) which have been shown to have detrimental biological effects. Biological evaluation of the oxides of phytosterols is significant in the context of increased dietary use of phytosterols in the drive to reduce cholesterol absorption.

AB - The synthesis and structural characterization of a series of oxides of stigmasterol is described providing a valuable series of reference standards for these oxides, analogous to the cholesterol oxidation products (COPs) which have been shown to have detrimental biological effects. Biological evaluation of the oxides of phytosterols is significant in the context of increased dietary use of phytosterols in the drive to reduce cholesterol absorption.

KW - Phytosterol oxidation products

KW - Stlgmasterol oxldes

UR - https://www.scopus.com/pages/publications/74849136548

U2 - 10.1021/jf9024745

DO - 10.1021/jf9024745

M3 - Article

C2 - 20025271

AN - SCOPUS:74849136548

SN - 0021-8561

VL - 58

SP - 1165

EP - 1173

JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

IS - 2

ER -

Synthesis and characterization of stigmasterol oxidation products

Abstract

Keywords

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