The application of molecular tethers in controlling axial chirality

Michael Reen; Timothy P. O’Sullivan

doi:10.2174/1570193X13666160510114626

The application of molecular tethers in controlling axial chirality

Michael Reen
, Timothy P. O’Sullivan

University College Cork

Research output: Contribution to journal › Article › peer-review

Abstract

Atropisomeric biaryl compounds are an attractive target in organic chemistry due to their abundance in nature and their utility as ligands in catalysis. Among the methods available for their synthesis, the use of chiral tethers offers very high levels of stereocontrol. In this article, we review the application of molecular tethers in controlling axial chirali-ty across a range of different ligands and natural products.

Original language	English
Pages (from-to)	206-218
Number of pages	13
Journal	Mini-Reviews in Organic Chemistry
Volume	13
Issue number	3
DOIs	https://doi.org/10.2174/1570193X13666160510114626
Publication status	Published - 1 Jun 2016

Keywords

Atropisomeric biaryl compound
Axial chirality
Biaryls
Stereoinduction
Synthesis
Tethers

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10.2174/1570193X13666160510114626

https://hdl.handle.net/10468/4119Licence: CC BY-NC-ND

Cite this

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abstract = "Atropisomeric biaryl compounds are an attractive target in organic chemistry due to their abundance in nature and their utility as ligands in catalysis. Among the methods available for their synthesis, the use of chiral tethers offers very high levels of stereocontrol. In this article, we review the application of molecular tethers in controlling axial chirali-ty across a range of different ligands and natural products.",

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KW - Atropisomeric biaryl compound

KW - Axial chirality

KW - Biaryls

KW - Stereoinduction

KW - Synthesis

KW - Tethers

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JF - Mini-Reviews in Organic Chemistry

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ER -

The application of molecular tethers in controlling axial chirality

Abstract

Keywords

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