The European Alliance Against Depression approach: an evidence-based program to reduce depression and suicidal behavior

The Global Burden of Disease studies have consistently highlighted the persisting burden of mental disorders worldwide. Public health emergencies such as the COVID-19 pandemic, war and conflict, and climate change have exacerbated many determinants of poor mental health, resulting in an increased prevalence of anxiety and depression worldwide. Despite substantial advancements in intervention and prevention programs, treatment gaps in depression and suicidal behavior persist. Addressing these gaps requires a multi-level approach involving both community and health services. This Perspective addresses the urgent need to strengthen mental health systems globally. The primary purpose of this Perspective is to discuss the four-level community-based approaches of the European Alliance Against Depression program, including evidence in support of its four-level intervention as a sustainable model for community-based mental health care that can be effectively adapted to various contexts, including current and future public health emergencies.