The gut microbiome as a modulator of healthy ageing

Tarini Shankar Ghosh; Fergus Shanahan; Paul W. O’Toole

doi:10.1038/s41575-022-00605-x

The gut microbiome as a modulator of healthy ageing

Tarini Shankar Ghosh
, Fergus Shanahan
, Paul W. O’Toole

University College Cork

Research output: Contribution to journal › Review article › peer-review

Abstract

The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct. In this Review, we explore targeted studies of the gut microbiome of older individuals and general cohort studies across geographically distinct populations. We also address the promise of the targeted restoration of microorganisms associated with healthier ageing.

Original language	English
Pages (from-to)	565-584
Number of pages	20
Journal	Nature Reviews Gastroenterology and Hepatology
Volume	19
Issue number	9
DOIs	https://doi.org/10.1038/s41575-022-00605-x
Publication status	Published - Sep 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/s41575-022-00605-x

Cite this

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abstract = "The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct. In this Review, we explore targeted studies of the gut microbiome of older individuals and general cohort studies across geographically distinct populations. We also address the promise of the targeted restoration of microorganisms associated with healthier ageing.",

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AB - The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct. In this Review, we explore targeted studies of the gut microbiome of older individuals and general cohort studies across geographically distinct populations. We also address the promise of the targeted restoration of microorganisms associated with healthier ageing.

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The gut microbiome as a modulator of healthy ageing

Abstract

UN SDGs

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