The human side of cancer biobanking

Eoin F. Gaffney; Deirdre Madden; Geraldine A. Thomas

doi:10.1007/978-1-60327-216-2_5

The human side of cancer biobanking

Eoin F. Gaffney
, Deirdre Madden
, Geraldine A. Thomas

School of Law

St James's Hospital
Imperial College Healthcare NHS Trust

Research output: Chapter in Book/Report/Conference proceedings › Chapter › peer-review

Abstract

The future success of translational research is critically dependent on the procurement and availability of high-quality tissue specimens linked to accurate histopathologic and clinical information about the individual banked specimen. The international community has awakened to this critical need only recently. Three major roadblocks have hindered the success of previous biobank consortiums: (1) Ethical issues surrounding patient consent and ownership of intellectual property, (2) Failure to properly preserve the molecular content of the tissue, and failure to reliably document clinical data linked to the specimen, and (3) Management issues: inadequate funding, competition for use of the tissue, inadequate personnel and facilities, and absence of dedicated database software. This chapter reviews these critical roadblocks and discusses international efforts to provide strategies to implement high-quality biobanks.

Original language	English
Title of host publication	Molecular Profiling
Subtitle of host publication	Methods and Protocols
Editors	Virginia Espina, Lance Liotta
Pages	59-77
Number of pages	19
DOIs	https://doi.org/10.1007/978-1-60327-216-2_5
Publication status	Published - 2012

Publication series

Name	Methods in Molecular Biology
Volume	823
ISSN (Print)	1064-3745

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Biobanking
Database
DNA
Ethic
Pathology
Protein
Quality control
RNA
Specimen
Tissue

Access to Document

10.1007/978-1-60327-216-2_5

Cite this

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KW - Biobanking

KW - Database

KW - DNA

KW - Ethic

KW - Pathology

KW - Protein

KW - Quality control

KW - RNA

KW - Specimen

KW - Tissue

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The human side of cancer biobanking

Abstract

Publication series

UN SDGs

Keywords

Access to Document

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