The Impact of Recent Developments in Technologies which Enable the Increased Use of Biocatalysts

Aoife M. Foley; Anita R. Maguire

doi:10.1002/ejoc.201900208

The Impact of Recent Developments in Technologies which Enable the Increased Use of Biocatalysts

Aoife M. Foley
, Anita R. Maguire

Research output: Contribution to journal › Review article › peer-review

Abstract

While biocatalytic transformations are very powerful in enantioselective synthesis, frequently occurring under mild conditions, and proceed with extraordinary selectivity, there are practical challenges associated with the use of biocatalysis, such as limited substrate scope, stability, and reusability. Recent technological developments, for example immobilization, continuous flow, and molecular biology, all contribute towards enhancing the use of enzymes in synthesis.

Original language	English
Pages (from-to)	3713-3734
Number of pages	22
Journal	European Journal of Organic Chemistry
Volume	2019
Issue number	23
DOIs	https://doi.org/10.1002/ejoc.201900208
Publication status	Published - 23 Jun 2019

Keywords

Biocatalysis
Flow chemistry
Immobilization
Molecular biology

Access to Document

10.1002/ejoc.201900208

Cite this

@article{0f070d95b6934ab4aa7fdcc0c43e6571,

title = "The Impact of Recent Developments in Technologies which Enable the Increased Use of Biocatalysts",

abstract = "While biocatalytic transformations are very powerful in enantioselective synthesis, frequently occurring under mild conditions, and proceed with extraordinary selectivity, there are practical challenges associated with the use of biocatalysis, such as limited substrate scope, stability, and reusability. Recent technological developments, for example immobilization, continuous flow, and molecular biology, all contribute towards enhancing the use of enzymes in synthesis.",

keywords = "Biocatalysis, Flow chemistry, Immobilization, Molecular biology",

author = "Foley, \{Aoife M.\} and Maguire, \{Anita R.\}",

note = "Publisher Copyright: {\textcopyright} 2019 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim",

year = "2019",

month = jun,

day = "23",

doi = "10.1002/ejoc.201900208",

language = "English",

volume = "2019",

pages = "3713--3734",

journal = "European Journal of Organic Chemistry",

issn = "1434-193X",

publisher = "Wiley-VCH Verlag",

number = "23",

}

TY - JOUR

T1 - The Impact of Recent Developments in Technologies which Enable the Increased Use of Biocatalysts

AU - Foley, Aoife M.

AU - Maguire, Anita R.

PY - 2019/6/23

Y1 - 2019/6/23

N2 - While biocatalytic transformations are very powerful in enantioselective synthesis, frequently occurring under mild conditions, and proceed with extraordinary selectivity, there are practical challenges associated with the use of biocatalysis, such as limited substrate scope, stability, and reusability. Recent technological developments, for example immobilization, continuous flow, and molecular biology, all contribute towards enhancing the use of enzymes in synthesis.

AB - While biocatalytic transformations are very powerful in enantioselective synthesis, frequently occurring under mild conditions, and proceed with extraordinary selectivity, there are practical challenges associated with the use of biocatalysis, such as limited substrate scope, stability, and reusability. Recent technological developments, for example immobilization, continuous flow, and molecular biology, all contribute towards enhancing the use of enzymes in synthesis.

KW - Biocatalysis

KW - Flow chemistry

KW - Immobilization

KW - Molecular biology

UR - https://www.scopus.com/pages/publications/85065827968

U2 - 10.1002/ejoc.201900208

DO - 10.1002/ejoc.201900208

M3 - Review article

AN - SCOPUS:85065827968

SN - 1434-193X

VL - 2019

SP - 3713

EP - 3734

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 23

ER -

The Impact of Recent Developments in Technologies which Enable the Increased Use of Biocatalysts

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this