The impact of the cephalic phase on postprandial blood glucose and satiety

Background and aims: The impact of cephalic phase on postprandial insulin response is well documented however its effects on postprandial blood glucose remain inconsistent. The purpose of the current study was to assess the impact of cephalic phase on postprandial blood glucose and satiety. Methods: Twelve participants were recruited and tested on two different occasions (i) with modified sham feeding (MSF) (ii) without MSF (Control) followed by white bread (50g available carbohydrate) consumption. Finger-prick blood samples were taken at regular interval for 120minto measure blood glucose. Measurements of satiety (hunger, fullness, desire to eat and prospective eating) were taken using 100mm visual analogue scales (VAS). Results: Blood glucose changes did not differ between the two occasions after 30, 60 and 120min. Similarly, there were no differences in satiety between the MSF test compared with the control. Conclusion: These findings suggest that the cephalic phase do not affect either postprandial blood glucose or satiety.