The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization

Stephen R. Stockdale; Jennifer Mahony; Pascal Courtin; Marie Pierre Chapot-Chartier; Jan Peter Van Pijkeren; Robert A. Britton; Horst Neve; Knut J. Heller; Bashir Aideh; Finn K. Vogensen; Douwe Van Sinderen

doi:10.1074/jbc.M112.444901

The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization

Stephen R. Stockdale
, Jennifer Mahony
, Pascal Courtin
, Marie Pierre Chapot-Chartier
, Jan Peter Van Pijkeren
, Robert A. Britton
, Horst Neve
, Knut J. Heller
, Bashir Aideh
, Finn K. Vogensen
, Douwe Van Sinderen

UMR1319 Micalis & AgroParisTech
Michigan State University
Max Rubner Institut
Department of Food Science
University of Copenhagen

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Siphoviridae virions often possess lytic domains facilitating host-penetration. Results: Tuc2009 and TP901-1 virions may contain full-length or truncated tail fibers, possessing or lacking a lytic domain, respectively. Conclusion: Phages with a lytic domain infect stationary phase cells better, whereas truncated derivatives have higher adsorption efficiencies. Significance: The heterogeneous phage population serves to most effectively infect bacteria where levels of cell wall crosslinkage differ.

Original language	English
Pages (from-to)	5581-5590
Number of pages	10
Journal	Journal of Biological Chemistry
Volume	288
Issue number	8
DOIs	https://doi.org/10.1074/jbc.M112.444901
Publication status	Published - 22 Feb 2013

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Stockdale, S. R., Mahony, J., Courtin, P., Chapot-Chartier, M. P., Van Pijkeren, J. P., Britton, R. A., Neve, H., Heller, K. J., Aideh, B., Vogensen, F. K., & Van Sinderen, D. (2013). The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization. Journal of Biological Chemistry, 288(8), 5581-5590. https://doi.org/10.1074/jbc.M112.444901

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title = "The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization",

abstract = "Background: Siphoviridae virions often possess lytic domains facilitating host-penetration. Results: Tuc2009 and TP901-1 virions may contain full-length or truncated tail fibers, possessing or lacking a lytic domain, respectively. Conclusion: Phages with a lytic domain infect stationary phase cells better, whereas truncated derivatives have higher adsorption efficiencies. Significance: The heterogeneous phage population serves to most effectively infect bacteria where levels of cell wall crosslinkage differ.",

author = "Stockdale, \{Stephen R.\} and Jennifer Mahony and Pascal Courtin and Chapot-Chartier, \{Marie Pierre\} and \{Van Pijkeren\}, \{Jan Peter\} and Britton, \{Robert A.\} and Horst Neve and Heller, \{Knut J.\} and Bashir Aideh and Vogensen, \{Finn K.\} and \{Van Sinderen\}, Douwe",

year = "2013",

month = feb,

day = "22",

doi = "10.1074/jbc.M112.444901",

language = "English",

volume = "288",

pages = "5581--5590",

journal = "Journal of Biological Chemistry",

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publisher = "American Society for Biochemistry and Molecular Biology Inc.",

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Stockdale, SR, Mahony, J, Courtin, P, Chapot-Chartier, MP, Van Pijkeren, JP, Britton, RA, Neve, H, Heller, KJ, Aideh, B, Vogensen, FK & Van Sinderen, D 2013, 'The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization', Journal of Biological Chemistry, vol. 288, no. 8, pp. 5581-5590. https://doi.org/10.1074/jbc.M112.444901

TY - JOUR

T1 - The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization

AU - Stockdale, Stephen R.

AU - Mahony, Jennifer

AU - Courtin, Pascal

AU - Chapot-Chartier, Marie Pierre

AU - Van Pijkeren, Jan Peter

AU - Britton, Robert A.

AU - Neve, Horst

AU - Heller, Knut J.

AU - Aideh, Bashir

AU - Vogensen, Finn K.

AU - Van Sinderen, Douwe

PY - 2013/2/22

Y1 - 2013/2/22

N2 - Background: Siphoviridae virions often possess lytic domains facilitating host-penetration. Results: Tuc2009 and TP901-1 virions may contain full-length or truncated tail fibers, possessing or lacking a lytic domain, respectively. Conclusion: Phages with a lytic domain infect stationary phase cells better, whereas truncated derivatives have higher adsorption efficiencies. Significance: The heterogeneous phage population serves to most effectively infect bacteria where levels of cell wall crosslinkage differ.

AB - Background: Siphoviridae virions often possess lytic domains facilitating host-penetration. Results: Tuc2009 and TP901-1 virions may contain full-length or truncated tail fibers, possessing or lacking a lytic domain, respectively. Conclusion: Phages with a lytic domain infect stationary phase cells better, whereas truncated derivatives have higher adsorption efficiencies. Significance: The heterogeneous phage population serves to most effectively infect bacteria where levels of cell wall crosslinkage differ.

UR - https://www.scopus.com/pages/publications/84874293279

U2 - 10.1074/jbc.M112.444901

DO - 10.1074/jbc.M112.444901

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C2 - 23300085

AN - SCOPUS:84874293279

SN - 0021-9258

VL - 288

SP - 5581

EP - 5590

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 8

ER -

The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization

Abstract

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