Abstract
Objective: To investigate the hypothalamic pituitary adrenal (HPA) axis response to a stressor in adolescents with inattentive type attention-deficit hyperactivity disorder symptoms (ADHD-I). Method: Salivary cortisol was measured in threshold inattentive (TI, n = 7), moderately inattentive (MI, n = 13) and no symptom (comparison) (n = 19) groups of healthy, young adolescents, based on symptom counts, prior to and after an induced social/cognitive stressor. Results: The TI group displayed a significant decrease in cortisol post stressor whereas both the MI and comparison groups showed an increase in cortisol. Conclusion: The diagnostic threshold of inattentive type ADHD shows HPA axis dysregulation whereas the more mild form does not show dysfunction.
| Original language | English |
|---|---|
| Pages (from-to) | 27-38 |
| Number of pages | 12 |
| Journal | Child Psychiatry and Human Development |
| Volume | 39 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Mar 2008 |
| Externally published | Yes |
Keywords
- Attention-deficit hyperactivity
- Cortisol
- HPA
- Inattention
- Stress
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