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The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder

  • Stephen V. Faraone
  • , Tobias Banaschewski
  • , David Coghill
  • , Yi Zheng
  • , Joseph Biederman
  • , Mark A. Bellgrove
  • , Jeffrey H. Newcorn
  • , Martin Gignac
  • , Nouf M. Al Saud
  • , Iris Manor
  • , Luis Augusto Rohde
  • , Li Yang
  • , Samuele Cortese
  • , Doron Almagor
  • , Mark A. Stein
  • , Turki H. Albatti
  • , Haya F. Aljoudi
  • , Mohammed M.J. Alqahtani
  • , Philip Asherson
  • , Lukoye Atwoli
  • Sven Bölte, Jan K. Buitelaar, Cleo L. Crunelle, David Daley, Søren Dalsgaard, Manfred Döpfner, Stacey Espinet, Michael Fitzgerald, Barbara Franke, Manfred Gerlach, Jan Haavik, Catharina A. Hartman, Cynthia M. Hartung, Stephen P. Hinshaw, Pieter J. Hoekstra, Chris Hollis, Scott H. Kollins, J. J. Sandra Kooij, Jonna Kuntsi, Henrik Larsson, Tingyu Li, Jing Liu, Eugene Merzon, Gregory Mattingly, Paulo Mattos, Suzanne McCarthy, Amori Yee Mikami, Brooke S.G. Molina, Joel T. Nigg, Diane Purper-Ouakil, Olayinka O. Omigbodun, Guilherme V. Polanczyk, Yehuda Pollak, Alison S. Poulton, Ravi Philip Rajkumar, Andrew Reding, Andreas Reif, Katya Rubia, Julia Rucklidge, Marcel Romanos, J. Antoni Ramos-Quiroga, Arnt Schellekens, Anouk Scheres, Renata Schoeman, Julie B. Schweitzer, Henal Shah, Mary V. Solanto, Edmund Sonuga-Barke, César Soutullo, Hans Christoph Steinhausen, James M. Swanson, Anita Thapar, Gail Tripp, Geurt van de Glind, Wim van den Brink, Saskia Van der Oord, Andre Venter, Benedetto Vitiello, Susanne Walitza, Yufeng Wang
  • SUNY Upstate Medical University
  • World Federation of ADHD
  • American Professional Society of ADHD and Related Disorders (APSARD)
  • Heidelberg University 
  • Zentrales-ADHS-Netz
  • The German Association of Child and Adolescent Psychiatry and Psychotherapy
  • University of Melbourne
  • Capital Medical University
  • The National Clinical Research Center for Mental Disorders
  • Beijing Key Laboratory of Mental Disorders
  • Asian Federation of ADHD
  • Chinese Society of Child and Adolescent Psychiatry
  • Massachusetts General Hospital
  • Harvard University
  • Monash University
  • Australian ADHD Professionals Association (AADPA)
  • Icahn School of Medicine at Mount Sinai
  • McGill University
  • Canadian ADHD Research Alliance (CADDRA)
  • Saudi ADHD Society
  • Israeli Society of ADHD (ISA)
  • Co-chair of the neurodevelopmental section in EPA (the European Psychiatric Association)
  • Universidade Federal do Rio Grande do Sul
  • Peking University
  • University of Southampton
  • Solent NHS Trust
  • New York University
  • University of Nottingham
  • University of Toronto
  • University of Washington
  • Seattle Children's Hospital
  • Saudi ADHD Society Medical and Psychological Committee
  • King Faisal Specialist Hospital and Research Centre
  • King Khalid University
  • King's College London
  • Moi University
  • Aga Khan University
  • African College of Psychopharmacology
  • African Association of Psychiatrists
  • Karolinska Institutet
  • Stockholm Health Care Services
  • Curtin University
  • Radboud University Nijmegen
  • Vrije Universiteit Brussel
  • International Collaboration on ADHD and Substance Abuse (ICASA) Foundation
  • Aarhus University
  • iPSYCH
  • University of Cologne
  • Canadian ADHD Resource Alliance (CADDRA)
  • Trinity College Dublin
  • Professional Board
  • University of Würzburg
  • University of Bergen
  • University of Groningen
  • Interdisciplinary Center Psychopathology and Emotion Regulation
  • ADHD Across the Lifespan Network from European College of Neuropsychopharmacology(ECNP)
  • University of Wyoming
  • University of California at Berkeley
  • University of California at San Francisco
  • Nottinghamshire Healthcare NHS Foundation Trust
  • NIHR MindTech MedTech Co-operative
  • Nottingham University Hospitals
  • Duke University
  • VU University Medical Centre Amsterdam
  • PsyQ
  • European Network Adult ADHD
  • DIVA Foundation
  • Neurodevelopmental Disorders Across Lifespan Section of European Psychiatric Association
  • Örebro University
  • Children's Hospital of Chongqing Medical University
  • National Research Center for Clinical Medicine of Child Health and Disease
  • Chinese Medical Association
  • The Asian Society for Child and Adolescent Psychiatry and Allied Professions
  • Tel Aviv University
  • Leumit Health Services
  • Israeli Society of ADHD
  • Israeli National Diabetes Council
  • Washington University St. Louis
  • Midwest Research Group
  • Universidade Federal do Rio de Janeiro
  • Instituto D'or de Pesquisa e Ensino
  • Brazilian Attention Deficit Association (ABDA)
  • University of British Columbia
  • University of Pittsburgh
  • Oregon Health and Science University
  • Université de Montpellier
  • INSERM U 1018 CESP-Developmental Psychiatry
  • University of Ibadan
  • University College Hospital, Ibadan
  • Universidade de São Paulo
  • Hebrew University of Jerusalem
  • The University of Sydney
  • Jawaharlal Institute of Postgraduate Medical Education and Research
  • Goethe University Frankfurt
  • German Psychiatric Association
  • European Network for Hyperkinetic Disorders (EUNETHYDIS)
  • University of Canterbury
  • Hospital Universitari Vall d'Hebron
  • Vall d'Hebron Research Institute
  • Autonomous University of Barcelona
  • Stellenbosch University
  • South African Special Interest Group for Adult ADHD
  • The South African Society of Psychiatrists/Psychiatry Management Group Management Guidelines for ADHD
  • World Federation of Biological Psychiatry
  • American Psychiatric Association
  • Association for NeuroPsychoEconomics
  • University of California at Davis
  • BYL Nair Charitable Hospital & TN Medical College
  • Northwell Health System
  • Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD)
  • National Center for Children with Learning Disabilities (NCLD)
  • University of Texas Health Science Center at Houston
  • University of Zurich
  • University of Basel
  • University of Southern Denmark
  • Centre of Child and Adolescent Mental Health
  • University of California at Irvine
  • Cardiff University
  • Okinawa Institute of Science and Technology Graduate University
  • Utrecht University of Applied Sciences
  • Amsterdam University Medical Centers
  • KU Leuven
  • European ADHD Guidelines Group
  • University of The Free State
  • University of Turin
  • Johns Hopkins University

Research output: Contribution to journalReview articlepeer-review

Abstract

Background: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. Methods: We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. Results: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents. Conclusions: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.

Original languageEnglish
Pages (from-to)789-818
Number of pages30
JournalNeuroscience and Biobehavioral Reviews
Volume128
DOIs
Publication statusPublished - Sep 2021

Keywords

  • ADHD
  • Brain
  • Course
  • Diagnosis
  • Genetics
  • Outcome
  • Treatment

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