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Tissue temperature measurements during interstitial laser therapy using Cr3+-doped crystals at the fiber tip

Research output: Chapter in Book/Report/Conference proceedingsConference proceedingpeer-review

Abstract

In this project a technique to optically measure the temperature is evaluated. The measurement is to be performed through optical fibres during photodynamic laser treatments or laser thermo therapy of malignant tumours. For this technique Cr3+-doped crystals were used. The lifetime of the ions' fluorescence were measured, since the fluorescence is strongly temperature dependent. A piece of a crystal was attached to the tip of an optical fibre. The crystal was excited at 635 nm, which is the wavelength most frequently used for photodynamic treatment. An accuracy in the temperature measurement of ± 0.3 °C was obtained for Cr:LiSAF in the region 20 - 70 °C. This is well within the requirements for this application. Alexandrite and Cr:YAG were also evaluated in this study, also yielding a very good accuracy. A laser treatment was simulated using pork chop as tissue phantom and the temperature was measured.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2003
PublisherOptica Publishing Group (formerly OSA)
Pages30-41
Number of pages12
ISBN (Electronic)0819450111
Publication statusPublished - 2003
Externally publishedYes
EventEuropean Conference on Biomedical Optics, ECBO 2003 - Munich, Germany
Duration: 22 Jun 2003 → …

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO 2003
Country/TerritoryGermany
CityMunich
Period22/06/03 → …

Keywords

  • Cr-ions
  • Temperature-dependent fluorescence

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