Transcriptional slippage in mxiE controls transcription and translation of the downstream mxiD gene, which encodes a component of the Shigella flexneri type III secretion apparatus

Christophe Penno; Claude Parsot

doi:10.1128/JB.188.3.1196-1198.2006

Transcriptional slippage in mxiE controls transcription and translation of the downstream mxiD gene, which encodes a component of the Shigella flexneri type III secretion apparatus

Christophe Penno
, Claude Parsot

Institut Pasteur Paris

Research output: Contribution to journal › Article › peer-review

Abstract

The Shigella flexneri transcription activator MxiE is produced by transcriptional slippage from two overlapping open reading frames. By using plasmids encoding a mxiD-lacZ translational fusion, we showed that transcriptional slippage in mxiE influences both transcription and translation of the downstream mxiD gene encoding an essential component of the type III secretion apparatus.

Original language	English
Pages (from-to)	1196-1198
Number of pages	3
Journal	Journal of Bacteriology
Volume	188
Issue number	3
DOIs	https://doi.org/10.1128/JB.188.3.1196-1198.2006
Publication status	Published - Feb 2006
Externally published	Yes

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10.1128/JB.188.3.1196-1198.2006

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abstract = "The Shigella flexneri transcription activator MxiE is produced by transcriptional slippage from two overlapping open reading frames. By using plasmids encoding a mxiD-lacZ translational fusion, we showed that transcriptional slippage in mxiE influences both transcription and translation of the downstream mxiD gene encoding an essential component of the type III secretion apparatus.",

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AB - The Shigella flexneri transcription activator MxiE is produced by transcriptional slippage from two overlapping open reading frames. By using plasmids encoding a mxiD-lacZ translational fusion, we showed that transcriptional slippage in mxiE influences both transcription and translation of the downstream mxiD gene encoding an essential component of the type III secretion apparatus.

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DO - 10.1128/JB.188.3.1196-1198.2006

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Transcriptional slippage in mxiE controls transcription and translation of the downstream mxiD gene, which encodes a component of the Shigella flexneri type III secretion apparatus

Abstract

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