Variation in treatment and outcome in the early stage oral cavity squamous cell carcinoma

Darragh S. Gogarty; Paul Lennon; Sandra Deady; J. Barry O’Sullivan; Orla McArdle; Mary Leader; Patrick Sheahan; James Paul O’Neill

doi:10.1007/s00405-016-4267-z

Variation in treatment and outcome in the early stage oral cavity squamous cell carcinoma

Darragh S. Gogarty
, Paul Lennon
, Sandra Deady
, J. Barry O’Sullivan
, Orla McArdle
, Mary Leader
, Patrick Sheahan
, James Paul O’Neill

School of Medicine

University College Dublin
Royal College of Surgeons in Ireland
National Cancer Registry Ireland

Research output: Contribution to journal › Article › peer-review

Abstract

This study aims to determine the survival impact of patient characteristics and treatment options associated with the early stage oral cavity squamous cell carcinoma, OCSCC. The methods are analysis of Irish cancer database examining T1/2, N0, and M0 cases of OCSCC from 1997 to 2007 inclusive. In total, 397 cases were identified. Anterolateral tongue accounted for 52.9 % of cases. Increased age at diagnosis and smoking are independent prognostic survival indicators associated with poorer outcomes. Surgery as the initial intervention was associated with significantly better survival outcomes, while surgery and adjuvant radiotherapy significantly worse outcomes. Surgical intervention is recommended as the first-line treatment in the early stage OCSCC in combination with elective neck dissection.

Original language	English
Pages (from-to)	953-960
Number of pages	8
Journal	European Archives of Oto-Rhino-Laryngology
Volume	274
Issue number	2
DOIs	https://doi.org/10.1007/s00405-016-4267-z
Publication status	Published - 1 Feb 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adult
Node negative
Oral cavity
Radiotherapy
Survival

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10.1007/s00405-016-4267-z

Cite this

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title = "Variation in treatment and outcome in the early stage oral cavity squamous cell carcinoma",

abstract = "This study aims to determine the survival impact of patient characteristics and treatment options associated with the early stage oral cavity squamous cell carcinoma, OCSCC. The methods are analysis of Irish cancer database examining T1/2, N0, and M0 cases of OCSCC from 1997 to 2007 inclusive. In total, 397 cases were identified. Anterolateral tongue accounted for 52.9 \% of cases. Increased age at diagnosis and smoking are independent prognostic survival indicators associated with poorer outcomes. Surgery as the initial intervention was associated with significantly better survival outcomes, while surgery and adjuvant radiotherapy significantly worse outcomes. Surgical intervention is recommended as the first-line treatment in the early stage OCSCC in combination with elective neck dissection.",

keywords = "Adult, Node negative, Oral cavity, Radiotherapy, Survival",

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doi = "10.1007/s00405-016-4267-z",

language = "English",

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TY - JOUR

T1 - Variation in treatment and outcome in the early stage oral cavity squamous cell carcinoma

AU - Gogarty, Darragh S.

AU - Lennon, Paul

AU - Deady, Sandra

AU - Barry O’Sullivan, J.

AU - McArdle, Orla

AU - Leader, Mary

AU - Sheahan, Patrick

AU - O’Neill, James Paul

PY - 2017/2/1

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N2 - This study aims to determine the survival impact of patient characteristics and treatment options associated with the early stage oral cavity squamous cell carcinoma, OCSCC. The methods are analysis of Irish cancer database examining T1/2, N0, and M0 cases of OCSCC from 1997 to 2007 inclusive. In total, 397 cases were identified. Anterolateral tongue accounted for 52.9 % of cases. Increased age at diagnosis and smoking are independent prognostic survival indicators associated with poorer outcomes. Surgery as the initial intervention was associated with significantly better survival outcomes, while surgery and adjuvant radiotherapy significantly worse outcomes. Surgical intervention is recommended as the first-line treatment in the early stage OCSCC in combination with elective neck dissection.

AB - This study aims to determine the survival impact of patient characteristics and treatment options associated with the early stage oral cavity squamous cell carcinoma, OCSCC. The methods are analysis of Irish cancer database examining T1/2, N0, and M0 cases of OCSCC from 1997 to 2007 inclusive. In total, 397 cases were identified. Anterolateral tongue accounted for 52.9 % of cases. Increased age at diagnosis and smoking are independent prognostic survival indicators associated with poorer outcomes. Surgery as the initial intervention was associated with significantly better survival outcomes, while surgery and adjuvant radiotherapy significantly worse outcomes. Surgical intervention is recommended as the first-line treatment in the early stage OCSCC in combination with elective neck dissection.

KW - Adult

KW - Node negative

KW - Oral cavity

KW - Radiotherapy

KW - Survival

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JF - European Archives of Oto-Rhino-Laryngology

IS - 2

ER -

Variation in treatment and outcome in the early stage oral cavity squamous cell carcinoma

Abstract

UN SDGs

Keywords

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