Research Profile

Tim O'Sullivan

Biography


Dr Tim O’Sullivan received his BSc Degree in Industrial Chemistry from the University of Limerick in 1997. He then went on to do a PhD in natural products synthesis under the supervision of Prof. Lew Mander at the Research School of Chemistry of the Australian National University from 1998 to 2001.

He worked as a postdoctoral researcher on the synthesis of Tamoxifen analogues with Prof. Mary Meegan in Trinity College Dublin from 2001 before taking up another postdoctoral fellowship with Prof. Pat Guiry in University College Dublin on the synthesis of novel Lipoxin analogues in 2003 . Following a period as research manager in UCD, he was appointed as Lecturer in Pharmaceutical Chemistry in the School of Pharmacy/Department of Chemistry/ABCRF in UCC in 2006.

He is a member of the Royal Society of Chemistry, the Marie Curie Alumni Association and COST Action 'CA21145 European Network for diagnosis and treatment of antibiotic-resistant bacterial infections (EURESTOP)'.

He was previously a member of COST Actions 'CA16107 EuroXanth' and 'CM1307 Targeted chemotherapy towards diseases caused by endoparasites'. 


Recent news:
See our Twitter profile for recent updates.

Research Interests

Synthesis of Natural Products and Medicinal Compounds
Our research is focused on developing new methods and strategies for the synthesis of bioactive, natural products. The underlying goal in this work is to improve upon existing techniques and to discover novel methods for assembling complex molecular targets. Ultimately, we aim to apply this knowledge to the development of more potent analogues of existing compounds, with a view to producing pharmaceutically relevant therapeutic agents.
 

New Drugs for Chagas Disease
The infectious agent of Chagas disease is Trypanosoma cruzi, which is closely related to the parasites which cause African sleeping sickness and leishmaniasis. The parasite usually enters the bloodstream of mammals through blood-sucking insects e.g. assassin bugs. Between 8 to 11 million people in Mexico, Central America, and South America are estimated to have Chagas disease, most of whom do not know they are infected. If untreated, infection is lifelong and can be life threatening. The acute phase of the disease is characterised by symptoms such as fever, fatigue, body aches, headache, rash, loss of appetite, diarrhoea and vomiting. In the chronic phase, the disease may result in cardiac complications, such as heart failure, or intestinal problems. The average life-time risk of developing one or more of these complications is about 30% with a fatality rate of around 50,000 people per annum.

More than 600 peroxides have been isolated from natural sources to date. Many have been found to be biologically active, displaying anti-cancer, anti-bacterial and anti-parasitic effects e.g. artemisinin. Recently, Plakortide P was reported to be highly selective against T. cruzi, in addition to displaying anti-leishmanial (L. chagasi) and anti-neuroinflammatory effects. We have developed a methodology for the asymmetric peroxidation of unsaturated aldehydes which has direct application to the synthesis of cycloperoxides. We are exploiting this chemistry to develop more potent analogues of Plakortide P.


Signalling Molecules - Disrupting Biofilm Formation in Cystic Fibrosis lung
Cystic Fibrosis (CF) is an inherited disease which affects about 1,500 Irish people. CF causes the body to produce an abnormally sticky fluid in the lungs which makes CF patients susceptible to serious bacterial infection.CF patients are faced with frequent stays in hospital as they are prone to infection by antibiotic-resistant bacteria. Approximately 60% CF patients have a chronic respiratory infection co-infected with multiple bacteria that settle into the thick mucus trapped in the airways. These bacteria have evolved a special type of defence where they excrete a chemical messenger on treatment with an antibiotic. These chemical messengers are cis-2-unsaturated fatty acids, with the most important being Diffusible Signal Factor (DSF). DSF leads to increased biofilm formation and resistance to antibiotics, factors that prolong the infection. We are developing compounds which inhibit the effects of DSF and thereby  shut down the bacterias’ defence mechanism.


Novel Anti-viral Therapies
There is a huge demand for new anti-retroviral drugs to increase patients treatment options, especially for drugs with enhanced safety profiles that display reduced side-effects and which are competitively priced. Given that NRTIs (Nucleotide Reverse Transcriptase Inhibitors) are currently used in first-line treatment in combination therapies, we are investigating their mode of action at a molecular level with the aim discovering  more potent NRTIs.The NRTIs currently marketed operate by prematurely terminating the HIV life cycle. A key step in this process involves the in vivo cleavage of the very strong Phosphorous-Oxygen bond which is either present in the original NRTI (e.g. Tenofovir) or is added by in vivo phorsphorylation. We believe that a more efficient inhibitor should result if the stronger Phosphorous-Oxygen bond is replaced with a more labile Phosphorous-Sulfur bond . The P-S bond is considered a bioisostere of the P-O bond, thus representing an excellent candidate for strategic substitution.


Postgraduate and postdoctoral positions:
We welcome applications from suitably qualified candidates seeking PhD funding via the Irish Research Council or the UCC Eli Lilly Scholarship Scheme.

We also welcome application from candidates seeing postdoctoral funding via the EU Marie Curie Fellowships.

Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
Design and Synthesis of Rationally Designed Novel AntiviralsIrish Research Council14-JAN-1930-APR-19€91,846.00
Government of Ireland Postgraduate Scholarship 2018 - Novel Dual Action Drugs for Chagas DiseaseIrish Research Council01-OCT-1814-MAR-23€102,125.00
Synthesis of novel quorum sensing inhibitors of DSFIrish Research Council01-OCT-1730-SEP-21€96,000.00
Synthesis and Evaluation of Novel Quorum Sensing InhibitorsNational University of Ireland (NUI)09-JAN-1708-JAN-20€72,000.00
H2020"655508 COMMANDEER MSCA-IF-2014"Dr T O'Sullivan :Horizon 202001-JUL-1530-JUN-17€187,866.00
Design and synthesis of novel sulfur-containing anti-HIV compoundsUCC Strategic Research Fund06-OCT-1405-OCT-17€47,310.00
Investigating the structure-activity relationship of current NRTIs with a view towards synthesising novel antiviral drug compounds.Irish Research Council01-OCT-1430-SEP-18€96,000.00
Rationally designed chiral cycloperoxides - new drugs for neglected diseases.Irish Research Council01-JAN-1431-DEC-17€96,000.00
Equipment bid - CEM Microwave reactorUCC Strategic Research Fund29-OCT-13€10,688.00
New therapies for cystic fibrosis lung infectionsScience Foundation Ireland23-JUL-1222-JUL-14€50,569.00
Towards an enantioselective synthesis of Plackortide P and its application to the development of drugs for the treatment of Chagas disease.European Union05-SEP-1104-SEP-13€204,584.00
Opensource chemistry questionbank for flexible, online teaching and assessment of students using SMILESNAIRTL31-AUG-1130-AUG-12€5,595.00
Towards an enantioslective synthesis of Plakortide P and its application to the development of drugs for the treatment of Chagas diseaseIrish Research Council for Science, Engineering & Technology (IRCSET)31-DEC-0930-DEC-13€72,009.00

Contract Researchers

 Researcher NameProjectRoleFunding Body
Dr Gangireddy SujeevanNovel resolvin analoguesResearch FellowIrish Research Council
Dr Rohit SharmaNovel antiviralsResearch FellowIrish Research Council
Dr Pavan KumarCOMMANDEERResearch FellowHorizon 2020
Dr Manoj GuptaPLAKORTIDEResearch FellowEuropean Framework Programme Seven (FP7)
Dr Julie MurtaghNew therapies for cystic fibrosis lung infectionsResearch AssistantScience Foundation Ireland

Publications

Book Chapters

 YearPublication
(2011)'Di-t-butylchlorosilane'
Hardgaden GC, O'Sullivan TP (2011) 'Di-t-butylchlorosilane' In: Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis. Chichester: Wiley. [Details]

Peer Reviewed Journals

 YearPublication
(2023)'Synthesis and evaluation of aromatic BDSF bioisosteres on biofilm formation and colistin sensitivity in pathogenic bacteria'
Gómez AC;Horgan C;Yero D;Bravo M;Daura X;O'Driscoll M;Gibert I;O'Sullivan TP; (2023) 'Synthesis and evaluation of aromatic BDSF bioisosteres on biofilm formation and colistin sensitivity in pathogenic bacteria'. European Journal of Medicinal Chemistry, 261 [DOI] [Details]
(2023)'Organocatalytic Asymmetric Peroxidation of g,d-Unsaturated ß-Keto Esters-A Novel Route to Chiral Cycloperoxides'
Hennessy MC;Gandhi H;O'Sullivan TP; (2023) 'Organocatalytic Asymmetric Peroxidation of g,d-Unsaturated ß-Keto Esters-A Novel Route to Chiral Cycloperoxides'. Molecules, 28 (11) [DOI] [Details]
(2023)'Investigation of halogenated furanones as inhibitors of quorum sensing-regulated bioluminescence in Vibrio harveyi'
Pinheiro J;Lyons T;Heras VL;Recio MV;Gahan CG;O'Sullivan TP; (2023) 'Investigation of halogenated furanones as inhibitors of quorum sensing-regulated bioluminescence in Vibrio harveyi'. Future Medicinal Chemistry, 15 (4) [DOI] [Details]
(2022)'Major structure-activity relationships of resolvins, protectins, maresins and their analogues'
Daly, Kevin; O'Sullivan, Killian; O'Sullivan, Timothy P. (2022) 'Major structure-activity relationships of resolvins, protectins, maresins and their analogues'. Future Medicinal Chemistry, 14 (24):1943-1960 [DOI] [Full Text] [Details]
(2022)'Synthesis and evaluation of novel furanones as biofilm inhibitors in opportunistic human pathogens'
Gómez, Andromeda-Celeste; Lyons, Thérèse; Mamat, Uwe; Yero, Daniel; Bravo, Marc; Daura, Xavier; Elshafee, Osama; Brunke, Sascha; Gahan, Cormac G.M.; O’Driscoll, Michelle; Gibert, Isidre; O’Sullivan, Timothy P. (2022) 'Synthesis and evaluation of novel furanones as biofilm inhibitors in opportunistic human pathogens'. European Journal of Medicinal Chemistry, 242 :114678-1-16 [DOI] [Full Text] [Details]
(2022)'Synthesis and Reactivity of Dihalofuranones'
Lyons T.A.; Gahan C.G.M.; O'Sullivan T.P. (2022) 'Synthesis and Reactivity of Dihalofuranones'. Letters In Organic Chemistry, 19 (8):662-667 [DOI] [Full Text] [Details]
(2022)'Recent developments in the practical application of novel carboxylic acid bioisosteres'
Horgan, Conor; O'Sullivan, Timothy P. (2022) 'Recent developments in the practical application of novel carboxylic acid bioisosteres'. Current Medicinal Chemistry, 29 (13):2203-2234 [DOI] [Full Text] [Details]
(2021)'Recent advances in the transesterification of β-keto esters'
M. C. Hennessy and T. P. O'Sullivan (2021) 'Recent advances in the transesterification of β-keto esters'. RSC Advances, 11 :22859-22920 [DOI] [Full Text] [Details]
(2020)'Synthesis and biological evaluation of novel thionucleosides'
O’Donovan, Fiona P.; O’Leary, Eileen M.; O’Sullivan, Timothy P. (2020) 'Synthesis and biological evaluation of novel thionucleosides'. Current Organic Chemistry, 24 (15):1717-1762 [DOI] [Full Text] [Details]
(2020)'Structure-activity relationships of furanones, dihydropyrrolones and thiophenones as potential quorum sensing inhibitors'
Lyons, Thérèse; Gahan, Cormac G. M.; O'Sullivan, Timothy P. (2020) 'Structure-activity relationships of furanones, dihydropyrrolones and thiophenones as potential quorum sensing inhibitors'. Future Medicinal Chemistry, 12 (21):1925-1943 [DOI] [Full Text] [Details]
(2020)'Modern synthetic approaches to phosphorus-sulfur bond formation in organophosphorus compounds'
Jones, David J.; O'Leary, Eileen M.; O'Sullivan, Timothy P. (2020) 'Modern synthetic approaches to phosphorus-sulfur bond formation in organophosphorus compounds'. Advanced Synthesis and Catalysis, 362 (14):2801-2846 [DOI] [Full Text] [Details]
(2020)'A Robust Methodology for the Synthesis of Phosphorothioates, Phosphinothioates and Phosphonothioates'
Jones, David J.; O'Leary, Eileen M.; O'Sullivan, Timothy P. (2020) 'A Robust Methodology for the Synthesis of Phosphorothioates, Phosphinothioates and Phosphonothioates'. Advanced Synthesis and Catalysis, 362 (9):1825-1830 [DOI] [Full Text] [Details]
(2019)'Sulfonamide-based diffusible signal factor analogs interfere with quorum sensing in Stenotrophomonas maltophilia and Burkholderia cepacia'
Pol Huedo, Vydyula P Kumar, Conor Horgan, Daniel Yero, Xavier Daura, Isidre Gibert & Timothy P O’Sullivan*, (2019) 'Sulfonamide-based diffusible signal factor analogs interfere with quorum sensing in Stenotrophomonas maltophilia and Burkholderia cepacia'. Future Medicinal Chemistry, 11 (13):1565-1582 [DOI] [Full Text] [Details]
(2019)'Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues'
An, SQ; Murtagh, J; Twomey, KB; Gupta, MK; O'Sullivan, TP; Ingram, R; Valvano, MA; Tang, JL (2019) 'Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues'. Nature Communications, 10 [DOI] [Full Text] [Details]
(2019)'An improved synthesis of adefovir and related analogues'
David J. Jones, Eileen M. O’Leary and Timothy P. O’Sullivan (2019) 'An improved synthesis of adefovir and related analogues'. Beilstein Journal Of Organic Chemistry, 15 :801-810 [DOI] [Full Text] [Details]
(2018)'Synthesis and application of phosphonothioates, phosphonodithioates, phosphorothioates, phosphinothioates and related compounds'
Jones, David J.; O'Leary, Eileen M.; O'Sullivan, Timothy P. (2018) 'Synthesis and application of phosphonothioates, phosphonodithioates, phosphorothioates, phosphinothioates and related compounds'. Tetrahedron Letters, 59 (49):4279-4292   [DOI] [Full Text] [Details]
(2018)'Efficient S-Acylation of Thiourea'
David J. Jones, Uday B. Rao Khandavilli, Eileen M. O’Leary, Simon E. Lawrence, Timothy P. O’Sullivan (2018) 'Efficient S-Acylation of Thiourea'. SynOpen, 2 (4):263-267 [DOI] [Full Text] [Details]
(2018)'Synthesis of the quorum sensing molecule Diffusible Signal Factor using the alkyne zipper reaction'
Kumar, VP; Gupta, MK; Horgan, C; O'Sullivan, TP (2018) 'Synthesis of the quorum sensing molecule Diffusible Signal Factor using the alkyne zipper reaction'. Tetrahedron Letters, 59 :2193-2195 [DOI] [Full Text] [Details]
(2018)'Synthesis of novel quinine analogs and evaluation of their effects on Trypanosoma cruzi'
Ceole, LF; Gandhi, H; Villamizar, LH; Soares, MJ; O'Sullivan, TP (2018) 'Synthesis of novel quinine analogs and evaluation of their effects on Trypanosoma cruzi'. Future Medicinal Chemistry, 10 :391-408 [DOI] [Full Text] [Details]
(2017)'Asymmetric Peroxidation of α,β-Unsaturated Aldehydes under Diarylprolinol Ether Catalysis'
K. O'Reilly, M. K. Gupta, H. Gandhi, V. P. Kumar, T. P. O'Sullivan. (2017) 'Asymmetric Peroxidation of α,β-Unsaturated Aldehydes under Diarylprolinol Ether Catalysis'. Current Organic Chemistry, 21 (19):2013-2016 [DOI] [Full Text] [Details]
(2017)'Synthesis of symmetrically and unsymmetrically substituted S,S-dialkyl phosphonodithioates'
David J. Jones; Eileen M. O'Leary; Timothy P. O'Sullivan (2017) 'Synthesis of symmetrically and unsymmetrically substituted S,S-dialkyl phosphonodithioates'. Tetrahedron Letters, 58 (44):4212-4214 [DOI] [Full Text] [Details]
(2017)'Preparation of γ,δ-unsaturated-β-ketoesters: Lewis acid-catalysed CH insertion of ethyl diazoacetate into α,β-unsaturated aldehydes'
Hirenkumar Gandhi and Timothy P. O'Sullivan (2017) 'Preparation of γ,δ-unsaturated-β-ketoesters: Lewis acid-catalysed CH insertion of ethyl diazoacetate into α,β-unsaturated aldehydes'. Tetrahedron Letters, 58 (36):3533-3535 [DOI] [Full Text] [Details]
(2017)'Advances in the synthesis of acyclic peroxides'
Gandhi, Hirenkumar; O'Reilly, Kate; Gupta, Manoj K.; Horgan, C.; O'Leary, Eileen M.; O'Sullivan, Timothy P. (2017) 'Advances in the synthesis of acyclic peroxides'. RSC Advances, 7 (32):19506-19556 [DOI] [Full Text] [Details]
(2016)'Cinchona-catalysed, Enantioselective Synthesis of β-Peroxycarboxylic Acids, β-Peroxyesters and β-Peroxyalcohols'
Kate O’Reilly, Manoj K. Gupta, Hirenkumar Gandhi, Vydyula P. Kumar, Kevin S. Eccles, Simon E. Lawrence and Timothy P. O’Sullivan (2016) 'Cinchona-catalysed, Enantioselective Synthesis of β-Peroxycarboxylic Acids, β-Peroxyesters and β-Peroxyalcohols'. Current Organic Chemistry, 20 (24):2633-2638 [DOI] [Full Text] [Details]
(2016)'The Application of Molecular Tethers in Controlling Axial Chirality'
Michael Reen and Timothy P. O'Sullivan (2016) 'The Application of Molecular Tethers in Controlling Axial Chirality'. Mini-Reviews in Organic Chemistry, 13 (3):206-218 [DOI] [Full Text] [Details]
(2015)'Synthesis of fluorinated oxygen- and sulfur-containing heteroaromatics'
Eileen M. O’Leary, David J. Jones, Fıona P. O’Donovan, Timothy P. O’Sullivan (2015) 'Synthesis of fluorinated oxygen- and sulfur-containing heteroaromatics'. Journal of Fluorine Chemistry, 176 :93-120 [DOI] [Full Text] [Details]
(2014)'Using Structure-Based Organic Chemistry Online Tutorials with Automated Correction for Student Practice and Review'
Timothy P. O’Sullivan and Gráinne C. Hargaden (2014) 'Using Structure-Based Organic Chemistry Online Tutorials with Automated Correction for Student Practice and Review'. Journal Of Chemical Education, 91 (11):1851-1854 [DOI] [Full Text] [Details]
(2013)'Recent applications of gallium and gallium halides as reagents in organic synthesis'
Gupta, MK,O'Sullivan, TP (2013) 'Recent applications of gallium and gallium halides as reagents in organic synthesis'. RSC Advances, :25498-25522 [DOI] [Full Text] [Details]
(2013)'Production of a chiral alcohol, 1-(3,4-dihydroxyphenyl)'
Sarah J. Brooks, Jasmina Nikodinovic, Leona Martin, Evelyn M. Doyle, Timothy O’Sullivan, Patrick J. Guiry, Lydie Coulombel, Zhi Li, Kevin E. O’Connor (2013) 'Production of a chiral alcohol, 1-(3,4-dihydroxyphenyl)'. Biotechnology Letters, 35 (5):779-783 [DOI] [Details]
(2011)'Lipoxin A4 and benzo-lipoxin A4 attenuate experimental renal fibrosis'
Börgeson E, Docherty NG, Murphy M, Rodgers K, Ryan R, O'Sullivan TP, Guiry PJ, Goldschmeding R, Higgins DF, Godson C; (2011) 'Lipoxin A4 and benzo-lipoxin A4 attenuate experimental renal fibrosis'. The Faseb Journal, 25 (9):2967-2979 [DOI] [Details]
(2008)'Synthesis of non-symmetric bis(oxazoline)-containing ligands and their application in the catalytic enantioselective Nozaki-Hiyama-Kishi allylation of benzaldehyde'
Hargaden GC, O'Sullivan TP, Guiry PJ; (2008) 'Synthesis of non-symmetric bis(oxazoline)-containing ligands and their application in the catalytic enantioselective Nozaki-Hiyama-Kishi allylation of benzaldehyde'. Organic and Biomolecular Chemistry, 6 (3):562-566 [DOI] [Details]
(2007)'Model studies toward the synthesis of the bioactive diterpenoid, harringtonolide'
O'Sullivan TP, Zhang H, Mander LN; (2007) 'Model studies toward the synthesis of the bioactive diterpenoid, harringtonolide'. Organic and Biomolecular Chemistry, 5 (16):2627-2635 [DOI] [Full Text] [Details]
(2007)'Aromatic lipoxin A4 and lipoxin B4 analogues display potent biological activities'
O'Sullivan TP, Vallin KS, Shah ST, Fakhry J, Maderna P, Scannell M, Sampaio AL, Perretti M, Godson C, Guiry PJ; (2007) 'Aromatic lipoxin A4 and lipoxin B4 analogues display potent biological activities'. Journal of Medicinal Chemistry, 50 (24):5894-5902 [DOI] [Details]
(2006)'Antiestrogenically active 2-benzyl-1,1-diarylbut-2-enes: synthesis, structure-activity relationships and molecular modeling study for flexible estrogen receptor agonists'
Lloyd, D. G., Smith, H. M., O'Sullivan, T. P., Knox, A. S., Zisterer, D. M. and M. J. Meegan.; (2006) 'Antiestrogenically active 2-benzyl-1,1-diarylbut-2-enes: synthesis, structure-activity relationships and molecular modeling study for flexible estrogen receptor agonists'. Medicinal Chemistry, 2 (2):147-168 [DOI] [Details]
(2005)'Synthesis, structure-activity relationships and antagonistic effects in human MCF-7 breast cancer cells of flexible estrogen receptor modulators'
Lloyd DG, Smith HM, O'Sullivan T, Zisterer DM, Meegan MJ; (2005) 'Synthesis, structure-activity relationships and antagonistic effects in human MCF-7 breast cancer cells of flexible estrogen receptor modulators'. Medicinal Chemistry, 1 (4):335-353 [DOI] [Details]
(2005)'Synthesis of dihydrofurans substituted in the 2-position'
Kilroy, T. G.,O'Sullivan, T. P.,Guiry, P. J.; (2005) 'Synthesis of dihydrofurans substituted in the 2-position'. European Journal of Organic Chemistry, (23):4929-4949 [DOI] [Details]
(2005)'The development of enantioselective rhodium-catalysed hydroboration of olefins'
Carroll, A. M.,O'Sullivan, T. P.,Guiry, P. J.; (2005) 'The development of enantioselective rhodium-catalysed hydroboration of olefins'. Advanced Synthesis and Catalysis, 347 (5):609-631 [DOI] [Details]
(2005)'Synthesis of quinazolinones and quinazolines'
Connolly, D. J.,Cusack, D.,O'Sullivan, T. P.,Guiry, P. J.; (2005) 'Synthesis of quinazolinones and quinazolines'. Tetrahedron, 61 (43):10153-10202 [DOI] [Details]
(2003)'An exploration of the potential of 4+2 cycloadditions of alpha-pyrones with indenones for the synthesis of the norditerpenoid tropone, Harringtonolide'
Mander, L. N.,O'Sullivan, T. P.; (2003) 'An exploration of the potential of 4+2 cycloadditions of alpha-pyrones with indenones for the synthesis of the norditerpenoid tropone, Harringtonolide'. Synlett, (9):1367-1369 [DOI] [Details]

Conference Publications

 YearPublication
(2022)8th International Electronic Conference on Medicinal Chemistry
Timothy P. O’Sullivan (2022) Small Molecule Inhibitors of Bacterial Quorum Sensin 8th International Electronic Conference on Medicinal Chemistry , 01-OCT-23 - 31-OCT-23 [Details]
(2019)Pharmacy Education 2019
Timothy P. O'Sullivan (2019) Application of a technology-assisted flipped classroom to promote & measure student engagement in pharmacy education Pharmacy Education 2019 , 24-JUN-19 - 24-JUN-19 [Details]
(2013)5th Eurovariety in Chemistry Education Conference
Timothy P. O'Sullivan and Grainne C. Hargaden (2013) Flexible, online teaching and assessment of organic chemistry using MarvinSketch and SMILES 5th Eurovariety in Chemistry Education Conference Limerick, Ireland, [Details]
(2013)5th Eurovariety in Chemistry Education Conference
J.J. Keating, E.M. O'Leary and T.P. O'Sullivan (2013) Teaching Chemistry Through ‘Discipline’ Eyes’ 5th Eurovariety in Chemistry Education Conference Limerick, Ireland, [Details]
(2013)5th Eurovariety in Chemistry Education Conference
Eileen M. O’Leary and Timothy P. O’Sullivan (2013) A PACT with pharmacy students 5th Eurovariety in Chemistry Education Conference Limerick, Ireland, [Details]

Electronic Article

 YearPublication
(2021)RTÉ Brainstorm: How do the new anti-Covid drugs work?.
Timothy P. O'Sullivan and J. J. Keating (2021) RTÉ Brainstorm: How do the new anti-Covid drugs work?. Electronic Article   [Details]
(2021)RTÉ Brainstorm: Why are viruses such challenging foes?.
Timothy P. O'Sullivan and J. J. Keating (2021) RTÉ Brainstorm: Why are viruses such challenging foes?. Electronic Article   [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2022SEFS Student-nominated Staff Award UCC SEFS
2021IRC ‘Jane Grimson Medal of Excellence’ (Michelle O'Driscoll) Irish Research Council
20192nd Place Prize - Eli Lilly Postgraduate Research Symposium (Therese Lyons) Eli Lilly
2018Thomas Mitchell Medal of Excellence (Dr Rohit Sharma) Irish Research Council
2017President's Award for Excellence in Teaching UCC
20171st Place Prize - Eli Lilly Postgraduate Research Symposium (David Jones) Eli Lilly
2016Best Poster Prize - RSC Organic Division Ireland Regional Meeting (Fiona O'Donovan) Royal Society of Chemistry
2016UCC Digital Champion Award UCC
2013President’s Awards for Research Into Innovative Forms of Teaching UCC
2008Tetrahedron Award for ‘Most Cited Paper 2005 – 2008' Tetrahedron

Professional Associations

 AssociationFunctionFrom / To
COST Action EURESTOP COST Action EURESTOP06-OCT-22 /
EU Marie Sklodowska-Curie Actions Expert Evaluator01-MAY-19 /
COST Action CA16107 EuroXanth Member23-JUL-19 / 15-SEP-21
Marie Curie Alumni Association Member29-MAR-19 /
COST Action CM1307 Targeted chemotherapy towards diseases caused by endoparasites 2014-2018 Member06-JUN-14 / 06-JUN-18
Royal Society of Chemistry Member01-JAN-13 /

Conference Contributions

 YearPublication
(2023)Recent Advances in Synthesis and Chemical Biology XXII,
Michelle O’Driscoll and Timothy P. O’Sullivan (2023) Synthesis of Novel Bioisosteres of the Autoinducer BDSF. [Poster Presentation], Recent Advances in Synthesis and Chemical Biology XXII, UCD, Dublin , 08-DEC-23 - 08-DEC-23. [Details]
(2023)Recent Advances in Synthesis and Chemical Biology XXII,
Emily Collins and Timothy P. O’Sullivan (2023) Novel Routes to Phosphonodithioate Antivirals. [Poster Presentation], Recent Advances in Synthesis and Chemical Biology XXII, UCD, Dublin , 08-DEC-23 - 08-DEC-23. [Details]
(2022)Recent Advances in Synthesis and Chemical Biology XXI,
Amit Upadhyay and Timothy P. O'Sullivan (2022) Creation of a library of novel inhibitors of Cryptosporidium IMPDH. [Poster Presentation], Recent Advances in Synthesis and Chemical Biology XXI, UCD, Dublin , 09-DEC-22 - 09-DEC-22. [Details]
(2022)Recent Advances in Synthesis and Chemical Biology XXI,
Michelle O’Driscoll and Timothy P. O'Sullivan (2022) Synthesis of N-acylated aryl sulfonamides as quorum sensing inhibitors of DSF. [Poster Presentation], Recent Advances in Synthesis and Chemical Biology XXI, UCD, Dublin , 09-DEC-22 - 09-DEC-22. [Details]
(2022)Recent Advances in Synthesis and Chemical Biology XXI,
Emily Collins and Timothy P. O’Sullivan (2022) Investigation of a Sulfur-Based Antiviral SATE Prodrug. [Poster Presentation], Recent Advances in Synthesis and Chemical Biology XXI, UCD, Dublin , 09-DEC-22 - 09-DEC-22. [Details]
(2022)8th International Electronic Conference on Medicinal Chemistry,
Timothy P. O'Sullivan (2022) Small molecule inhibitors of bacterial quorum sensing. [Invited Lectures (Conference)], 8th International Electronic Conference on Medicinal Chemistry, Online , 01-NOV-22 - 30-NOV-22. [Details]
(2022)20th Annual Eli Lilly Postgraduate Research Symposium,
Amit Upadhyay and Timothy P. O'Sullivan (2022) Strategy for the development of novel drugs against Cryptosporidiosis. [Oral Presentation], 20th Annual Eli Lilly Postgraduate Research Symposium, UCC , 08-SEP-22 - 08-SEP-22. [Details]
(2022)GP2A Annual Conference 2022,
Amit Upadhyay and Timothy P. O’Sullivan (2022) Design and synthesis of novel drugs for the treatment of cryptosporidiosis. [Oral Presentation], GP2A Annual Conference 2022, Trinity College Dublin , 25-AUG-22 - 25-AUG-22. [Details]
(2022)73rd Irish Universities Chemistry Research Colloquium,
Amit Upadhyay and Timothy P. O’Sullivan (2022) Development of a synthetic route to novel IMPDH inhibitors. [Poster Presentation], 73rd Irish Universities Chemistry Research Colloquium, UCD, Dublin , 16-JUN-22 - 17-JUN-22. [Details]
(2022)73rd Irish Universities Chemistry Research Colloquium,
Mary C. Hennessy and Timothy P. O’Sullivan (2022) Preparation of 1,2-Dioxolanes via the Enantioselective Peroxidation of γ,δ-Unsaturated-β-Keto Esters. [Poster Presentation], 73rd Irish Universities Chemistry Research Colloquium, UCD, Dublin , 16-JUN-22 - 17-JUN-22. [Details]
(2021)27th SCI Annual Review Meeting,
Mary C. Hennessy and Timothy P. O'Sullivan (2021) Synthesis and Asymmetric Peroxidation of γ,δ-Unsaturated-β-Keto Esters en Route to 1,2-Dioxolanes. [Poster Presentation], 27th SCI Annual Review Meeting, London , 01-DEC-21 - 01-DEC-21. [Details]
(2021)19th Annual Eli Lilly Postgraduate Research Symposium,
Mary C. Hennessy and Timothy P. O'Sullivan (2021) Novel Cycloperoxides for Chagas Disease. [Oral Presentation], 19th Annual Eli Lilly Postgraduate Research Symposium, Online , 15-OCT-21 - 15-OCT-21. [Details]
(2021)EuroXanth 4th Annual Conference,
Conor Horgan and Timothy P. O'Sullivan (2021) Design and synthesis of potential quorum sensing inhibitors of Xylella fastidiosa. [Oral Presentation], EuroXanth 4th Annual Conference, Virtual , 30-JUN-21 - 30-JUN-21. [Details]
(2021)Technological University Dublin - Chemistry Seminar Series,
Timothy P. O'Sullivan (2021) Disrupting microbial resistance using small signal molecules. [Invited Seminars/Guest Lectures], Technological University Dublin - Chemistry Seminar Series, Online , 16-APR-21 - 16-APR-21. [Details]
(2021)GP2A Drug discovery in the era of antimicrobial resistance,
Timothy P. O'Sullivan (2021) Synthesis and evaluation of novel quorum sensing inhibitors of Diffusible Signal Factor. [Oral Presentation], GP2A Drug discovery in the era of antimicrobial resistance, Online , 03-MAR-21 - 03-MAR-21. [Details]
(2020)18th Annual Eli Lilly Postgraduate Research Symposium,
Conor Horgan and Timothy P. O'Sullivan (2020) Design and Synthesis of Bioisosteric Analogues of BDSF/DSF. [Oral Presentation], 18th Annual Eli Lilly Postgraduate Research Symposium, University College Cork , 23-OCT-20 - 23-OCT-20. [Details]
(2019)17th Annual Eli Lilly Postgraduate Research Symposium,
Therese Lyons, Timothy P. O'Sullivan and Cormac Gahan (2019) Synthesis and Evaluation of Novel Quorum Sensing Inhibitors. [Oral Presentation], 17th Annual Eli Lilly Postgraduate Research Symposium, University College Cork , 11-OCT-19. [Details]
(2019)Pharmacy Education 2019,
Timothy P. O'Sullivan (2019) Application of a technology-assisted flipped classroom to promote & measure student engagement in pharmacy education. [Oral Presentation], Pharmacy Education 2019, University of Manchester, Manchester , 24-JUN-19 - 24-JUN-19. [Details]
(2019)RSC Organic Division Ireland Regional Meeting 2019,
Timothy P. O'Sullivan (2019) Towards the synthesis of sulfur-based antivirals. [Invited Oral Presentation], RSC Organic Division Ireland Regional Meeting 2019, University College Dublin, Dublin , 07-JUN-19 - 07-JUN-19. [Details]
(2019)41st All-Ireland Schools of Pharmacy Conference,
Thérèse A. Lyons, Cormac Gahan and Timothy P. O’Sullivan (2019) Synthesis and Evaluation of Brominated Furanones as Novel Quorum Sensing Inhibitors of Autoinducer-2. [Poster Presentation], 41st All-Ireland Schools of Pharmacy Conference, Trinity College Dublin, Dublin , 17-APR-19 - 18-APR-19. [Details]
(2018)CIRTL Seminar Series,
Timothy P. O'Sullivan (2018) Active learning approaches. [Oral Presentation], CIRTL Seminar Series, University College Cork , 20-FEB-18. [Details]
(2018)Recent Advances in Synthesis and Chemical Biology XVII,
Thérèse A. Lyons, Timothy P. O’Sullivan, Cormac Gahan (2018) Synthesis and Evaluation of Novel Quorum Sensing Inhibitors. [Poster Presentation], Recent Advances in Synthesis and Chemical Biology XVII, Dublin, Ireland , 07-DEC-18. [Details]
(2018)Recent Advances in Synthesis and Chemical Biology XVII,
Conor Horgan and Timothy P. O’Sullivan (2018) Synthesis of Novel Quorum Sensing Inhibitors of DSF. [Poster Presentation], Recent Advances in Synthesis and Chemical Biology XVII, Dublin, Ireland , 07-DEC-18. [Details]
(2017)European Lead Factory Chemistry Event,
David J. Jones, Eileen M. O'Leary and Timothy P. O'Sullivan (2017) Early studies in the preparation and evaluation of a new drug template for the treatment of HIV. [Oral Presentation], European Lead Factory Chemistry Event, Beerse, Belgium , 06-NOV-17 - 07-NOV-17. [Details]
(2017)XVII International Conference on Heterocycles in Bioorganic Chemistry,
Fíona O’Donovan, Eileen M. O’Leary, Timothy P. O’Sullivan (2017) Towards the Synthesis of Novel Sulfur-Containing Antiviral Analogues. [Oral Presentation], XVII International Conference on Heterocycles in Bioorganic Chemistry, NUIG, Galway , 31-MAY-17 - 31-MAY-17. [Details]
(2016)Antiparasitic Chemotherapy for Human and Veterinary Use - 3rd COST Action CM1307 Conference,
Hirenkumar Gandhi, Timothy P. O’Sullivan, Ligia F. Ceole, Luz H. Villamizar, Maurilio J. Soares (2016) Modelling, synthesis and evaluation of novel quinine analogues new drugs for chagas disease. [Poster Presentation], Antiparasitic Chemotherapy for Human and Veterinary Use - 3rd COST Action CM1307 Conference, Madrid, Spain , 24-OCT-16 - 25-OCT-16. [Details]
(2016)31st International Symposium on Chromatography (ISC2016),
Jones, D.; O’Leary, E.M.; O’Sullivan, T.P. (2016) Dithiophosphonate Analogues of Acyclic Nucleoside Reverse Transcriptase Inhibitors Synthesis, Isolation and Analysis of Key Intermediates. [Poster Presentation], 31st International Symposium on Chromatography (ISC2016), University College Cork, Cork , 29-AUG-16. [Details]
(2016)31st International Symposium on Chromatography (ISC2016),
O’Donovan, F.P.; O’Leary, E.M.; O’Sullivan, T.P. (2016) Synthesis and analysis of novel sulfur-containing antiviral analogues. [Poster Presentation], 31st International Symposium on Chromatography (ISC2016), University College Cork, Cork , 29-AUG-16. [Details]
(2016)31st International Symposium on Chromatography (ISC2016),
Horgan, C., Kumar, V. P. and O’Sullivan T. P. (2016) Synthesis And Characterisation Of Novel Analogues Of Diffusible Signal Factor. [Poster Presentation], 31st International Symposium on Chromatography (ISC2016), University College Cork, Cork , 29-AUG-16. [Details]
(2016)31st International Symposium on Chromatography (ISC2016),
Gandhi, H., and O’Sullivan T. P. (2016) Asymmetric Peroxidation Of a,b-Unsaturated Aldehydes And Determination Of Enantioselectivity By Chiral HPLC. [Poster Presentation], 31st International Symposium on Chromatography (ISC2016), University College Cork, Cork , 29-AUG-16. [Details]
(2016)RSC Organic Division Ireland Regional Meeting 2016,
Fíona P. O’Donovan, Timothy P. O’Sullivan, Eileen M. O’Leary (2016) Towards the synthesis of novel sulfur-containing antiviral analogues. [Poster Presentation], RSC Organic Division Ireland Regional Meeting 2016, Dublin . [Details]
(2015)Variety in Chemistry Education Physics Higher Education Conference 2015,
Timothy P. O'Sullivan (2015) The use of online, formative assessment for contextualising key physicochemical concepts for pharmacy students. [Oral Presentation], Variety in Chemistry Education Physics Higher Education Conference 2015, University of Nottingham, UK , 20-AUG-15 - 20-AUG-15. [Details]
(2015)Pharmacy Education Conference 2015,
Eileen M. O'Leary, J. J. Keating and Timothy P. O'Sullivan (2015) The use of online, formative assessment for contextualising key physicochemical concepts underpinning drug action. [Poster Presentation], Pharmacy Education Conference 2015, Manchester , 29-JUN-15 - 29-JUN-15. [Details]
(2015)Royal Society of Chemistry Organic Division Regional Symposium,
Timothy P. O'Sullivan (2015) New methods for the synthesis of chiral peroxides. [Oral Presentation], Royal Society of Chemistry Organic Division Regional Symposium, University College Cork, Cork , 17-APR-15 - 17-APR-15. [Details]
(2014)Recent Advances in Synthesis and Chemical Biology XIII,
Timothy P. O’Sullivan and Hirenkumar Gandhi (2014) SYNTHESIS AND MOLECULAR-DOCKING STUDIES OF QUININE ANALOGUES AS POTENTIAL INHIBITORS OF TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE (TcTR). [Poster Presentation], Recent Advances in Synthesis and Chemical Biology XIII, Dublin , 12-DEC-14. [Details]
(2014)Adopting Courses from Traditional Face-to-Face to Online and Blended Learning,
T. P. O'Sullivan (2014) How to create meaningful continuous assessment questions with feedback on Blackboard. [Invited Lectures (Workshops)], Adopting Courses from Traditional Face-to-Face to Online and Blended Learning, University College Cork, Cork , 13-JUN-14 - 13-JUN-14. [Details]
(2013)5th Eurovariety in Chemistry Education Conference,
Timothy P. O'Sullivan (2013) Flexible, online teaching and assessment of organic chemistry using MarvinSketch and SMILES. [Oral Presentation], 5th Eurovariety in Chemistry Education Conference, Limerick, Ireland , 03-JUL-13 - 05-JUL-13. [Details]
(2013)Synthesis of Bioactive Molecules VIII,
Dr Andrew J Whitehead, GlaxoSmithKline; Prof Mary Meegan, Trinity College Dublin; Dr Marie Kissane, Eli Lilly; Prof David O’Hagan, University of St Andrews; Dr Hugues Miel, Almac Discovery; Dr AnnMarie O'Donoghue, University of Durham. (2013) Synthesis of Bioactive Molecules. [Conference Organising Committee Member], Synthesis of Bioactive Molecules VIII, University College Cork, Cork , 14-JUN-13 - 14-JUN-13. [Details]
(2013)RICT 2013 - Discovery and Selection - When Chemical Biology meets Drug Design,
Julie Murtagh, Robert Ryan, Timothy P. O’Sullivan (2013) INTERFERENCE WITH BACTERIAL CELL-CELL SIGNALLING USING SYNTHETICALLY GENERATED UNSATURATED FATTY ACIDS. [Poster Presentation], RICT 2013 - Discovery and Selection - When Chemical Biology meets Drug Design, Nice, France . [Details]
(2013)65th Irish Universities Chemistry Research Colloquium,
Kate O’ Reilly, Manoj K. Gupta, Timothy P. O’ Sullivan (2013) Enantioselective Peroxidaton of Unsaturated Aldehydes – A New Route to Plakortide P. [Poster Presentation], 65th Irish Universities Chemistry Research Colloquium, Dublin, Ireland . [Details]
(2012)North West Organic Chemistry Symposium,
G.C. Hargaden and T.P. O’Sullivan (2012) Chemnet - Open source chemistry question bank for flexible, online teaching and assessment of students using SMILES. [Poster Presentation], North West Organic Chemistry Symposium, Liverpool . [Details]
(2012)North West Organic Chemistry Symposium,
Michael Reen and Timothy P. O'Sullivan (2012) Development of Novel Chiral Tethers for Controlling Intermolecular Aryl-Aryl Coupling and Application in the Synthesis of Gomisin M1. [Poster Presentation], North West Organic Chemistry Symposium, Liverpool . [Details]
(2012)North West Organic Chemistry Symposium,
Kate O'Reilly, Manoj K. Gupta and Timothy P. O'Sullivan (2012) Organocatalytic enantioselective peroxidation of unsaturated aldehydes - a new route to bioactive cycloperoxides. [Poster Presentation], North West Organic Chemistry Symposium, Liverpool . [Details]
(2011)XXth Conference of the Groupement des Pharmacochimistes de l'Arc Atlantique,
Kate O'Reilly and Timothy P. O'Sullivan (2011) Towards an enantioselective systhesis of Plakortide P and its application towards drug development. [Poster Presentation], XXth Conference of the Groupement des Pharmacochimistes de l'Arc Atlantique, Cork . [Details]

Committees

 CommitteeFunctionFrom / To
SEFS Undergraduate Affairs Committee Member2022 /
SOP Teaching & Curriculum Committee Member2021 /
Academic Council Member2021 /
SOP Research and Graduate Studies Committee Member2019 /
PhD Programme in Organic and Pharmaceutical Chemistry Programme Co-ordinator2018 /
Chemistry Teaching and Examinations Committee Member2015 /
Chemistry Staff/Student Committee Member2014 /
School of Pharmacy Board Member2006 /
School of Chemistry Board Member2006 /
BSc Chemistry of Pharmaceutical Compounds Management Committee CPC3 Year Co-ordinator2006 /
Pharmacy Timetable Working Group Chair2014 / 2022
SOP Research Ethics Committee Member2018 / 2020
SOP Executive Member2019 / 2020
SOP Promotion of Pharmacy Committee Member2014 / 2019
COST Action CM1307 Targeted chemotherapy towards diseases caused by endoparasites Member2014 / 2018
Working group on PSI MPharm accreditation Member2015 / 2016
MPharm Curriculum Planning Group Member2010 / 2010

Employment

 EmployerPositionFrom / To
University College Cork Lecturer in Pharmaceutical Chemistry20-SEP-06 / 20-FEB-15
Centre for Synthesis and Chemical Biology, University College Dublin Research Manager07-FEB-05 / 15-SEP-06
Centre for Synthesis and Chemical Biology, University College Dublin Postdoctoral Fellow10-FEB-03 / 06-FEB-05
School of Pharmacy, Trinity College Dublin Postdoctoral Fellow05-NOV-01 / 24-JAN-03

Education

 YearInstitutionQualificationSubject
2020UCC Postgraduate Diploma in Teaching and Learning in Higher EducationTeaching and Learning in Higher Education
2015UCC Postgrad Certificate in Teaching & Learning in Higher EducationTeaching and Learning in HE
2001ANU, Canberra PhDOrganic Synthesis
2001Charles Sturt University, NSW Graduate DiplomaInformation Technology
1997UL, Limerick BScIndustrial Chemistry

Outreach Activities

 Description

2021: RTE Brainstorm Contributor (Dec '21)

2021: Tutor to Irish International Chemistry Olympiad Team (June '21)

2021: RTE Brainstorm contributor (Jan '21)

2019: Cork Carnival of Science - Chemistry (22/06/19)

2013: UCC Doctoral Student Showcase (Kate O’Reilly)

2008: UCC Summer Academy for Transition Year Students

Journal Activities

 JournalRoleTo / From
Advanced Synthesis & Catalysis Referee-
Journal Of Organic Chemistry Referee-
Journal Of Chemical Education Referee-
Future Medicinal Chemistry Referee-
Monatshefte Für Chemie - Chemical Monthly Referee-
Tetrahedron Letters Referee-
Chemical Society Reviews Referee-
Chemical Communications Referee-
Organic Chemistry Frontiers Referee-
Organic And Biomolecular Chemistry Referee-

Other Activities

 Description

2022: Digital Badge in Fostering Academic Integrity in Learning and Teaching (UCC)

2022: Sustainable Development Goals Workshop (UCC)

2022: Teaching for all (UCC)

2021: Irresponsible Research Practices (Epigeum Online)

2021: Good Research Conduct (Epigeum Online)

2021: Fire Safety Essentials Refresher Training

2019: Safety and Health (Epigeum Online)

2019: Intellectual Property (Epigeum Online)

2019: Conflict of Interest (Epigeum Online)

2019: Research Integrity (Epigeum Online)

2019: Excel Training Level 2

2019: Excel Training Level 1

2019: Advanced Canvas Training

2019: Canvas Training

2019: VDU Referesher Training

2018: Fire extinguisher training

2018: Fire Safety Essentials Refresher Training

2018: GDPR Compliance in the Republic of Ireland Workplace Fundamentals

2018:TUSLA ‘Introduction to Children First’ Elearning Programme

2017: Manual Handling Course (UCC)

2017: Online training in Equality and Diversity (UCC) 

2017: Google Forms Training (UCC)

2017: Unconscious Bias Training (UCC)

2016: OSCEology training (University of Toronto/UCC)

2016: Storyline training (UCC)

2015: Fire Marshall Training (UCC)

2014: Chemical Spill Response Training (UCC)

2013: PhD Supervisor Workshop - The Viva and Beyond (UCC)

2019: Hosted Erasmus summer exchange research student from Sigma Clermont, France (Laurie Bibens)

2019: Hosted CoMH SURE summer research bursary student (Ciara Kenny, MPharm 2)

2017: Hosted SEFS summer research bursary student (Aisling Foley, Chemistry 3)

2016: Hosted SEFS summer research bursary student (Conor Horgan, Chemistry 3)

2016: Hosted Erasmus summer exchange research student from École des Mines d'Albi-Carmaux (Maël Brehonnet)

2015: Hosted Erasmus summer exchange research student from Université de Nantes (Jessica Robin)


2011: Hosted Erasmus summer exchange research student from Ecole Nationale Supérieure de Chimie de Clermont-Ferrand (Fallia Aribi)

2009: Hosted Erasmus summer exchange research student from Ecole Nationale Supérieure de Chimie de Clermont-Ferrand (Clementine Bouvet).

2008: Hosted Erasmus summer exchange research student from Ecole Nationale Supérieure de Chimie de Clermont-Ferrand (Julie Movellan).                   

Teaching Activities

Teaching Interests

Currently

PF1009 - Introduction to Pharmaceutical Chemistry

PF2012 - Pharmaceutical Analysis

PF3012 - Respiratory, Musculoskeletal and Dermatology Systems

CM3001 - Organic Synthesis, Intermediates and Heterocycles

CM3110 - Pharmaceutical Solids and Technology

CM4001 - Advanced Organic Synthesis and Reactivity

CM7005 - Theory and Application of Computational Chemistry 

Previously

CM1100 - History of Chemistry

CM1005 - Introductory Chemistry for Food and Nutritional Scientists

CM3028 - Scientific Communication and Information Literacy Skills

Recent Postgraduates

 Graduation YearStudent NameInstitutionDegree TypeThesis Title
2023Mary Hennessy NUI (UCC)PHDSynthesis of novel cycloperoxides
2023Hirenkumar Gandhi NUI (UCC)PHDSynthesis of chiral cycloperoxides
2022Kevin Daly NUI (UCC)Master of ResearchComputational analysis and partial synthesis of resolvin analogues
2022Conor Horgan NUI (UCC)PHDSynthesis of novel quorum sensing inhibitors of DSF
2022Therese Lyons NUI (UCC)PHDSynthesis and evaluation of novel quorum sensing inhibitors
2019David Jones NUI (UCC)PHDDesign and Synthesis of Novel Sulfur-containing Antiviral Compounds
2016Michael Reen NUI (UCC)PHDThe development of novel chiral tethers for controlling intramolecular aryl-aryl coupling and their application in the synthesis of Gomisin M1 and analogues
2014Kate O'Reilly NUI (UCC)PHDTowards the enantioselective synthesis of Plakortide P and its application to the development of drugs for the treatment of Chagas Disease

Current Postgraduate Students

 StudentDegree Type
O'Driscoll Michelle Doctoral Degree
Collins Emily Agnes Doctoral Degree
Upadhyay Amit Doctoral Degree

Research Information

Internal Collaborators

 NameInstituteCountry
Dr Cormac Gahan APC & School of Pharmacy, UCCIRELAND

External Collaborators

 NameOrganisation / InstituteCountry
Prof Isidre Gibert Universitat Autònoma de Barcelona, Institut de Biotecnologia i de BiomedicinaSPAIN
Dr. Slavena Vylkova Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI)GERMANY
Maurilio José Soares Instituto Carlos ChagasBRAZIL
Prof Monique Van Hoek School of Systems Biology and the National Center for Biodefense and Infectious Diseases, George Mason UniversityU.S.A.
Prof Karin Sauer Binghamton Center for Biofilm Research, Binghamton UniversityU.S.A.
Prof Evelyn Murphy Conway Institute of Biomolecular & Biomedical Research, UCDIRELAND

Contact details

Search profiles by name

Search profiles by topic

School of Pharmacy

Cógaisíocht

Cavanagh Pharmacy Building Room UG06 University College Cork

Top