Throughout his research career, Dr Verma has published several high impact papers in leading peer-reviewed research journals including, crystal growth and design, CrystEngComm, International Journal of Pharmaceutics, Chemical Engineering Journal, etc. Two of these publications have been featured on the front covers of ‘CrystEngComm’ and ‘Chemical Engineering and Technology’. He is also an inventor, with a US patent (US20230111202A1) granted for a nanoparticle generation and isolation technology.
As a reviewer for journal like Powder Technology, CrystEngComm, Crystal Growth & Design, Journal of Molecular Liquids, etc., Dr Verma contributes to the scientific community beyond his own research. He has also mentored early career researchers, including supporting a successful Marie Sklodowska Curie Action's (MSCA) postdoctoral fellowship application. In 2018, he organised the ‘British association of Crystal Growth student day’ conference at the University of Limerick, Ireland.
Dr Verma’s current research focusses developing a platform for the sustainable purification and separation of (bio)pharmaceuticals, alongside exploring secondary processing of (bio)pharmaceuticals and investigating peptide self-assembly for innovative drug delivery technologies.
-Peptide Self Assembly
-Crystal Engineering
-Secondary processing of (bio)Pharmaceuticals
-Engineered surfaces
-Lipid nanoparticles
PE 1003: Introduction t Process and Chemical Engineering
PE 1813: Fluid Mechanics and Particle Processing
PE 2810: Chemical Engineering Project
Biography
Dr Vivek Verma is the UCC Future Pharmaceuticals Lecturer in the Process and Chemical Engineering Department within the School of Engineering and Architecture. A leading young researcher in the field of (bio)pharmaceutical nucleation and crystallisation, Dr Verma was awarded the prestigious Marie Sklodowska Curie Individual Fellowship in 2021 funded by the European Union to collaborate with Professor Jerry Heng in the Department of Chemical Engineering at Imperial College London. He is currently funded by the Science Foundation Ireland through the SFI-IRC Pathways Fellowship, focussing on the templated crystallisation of oligonucleotide drugs.Throughout his research career, Dr Verma has published several high impact papers in leading peer-reviewed research journals including, crystal growth and design, CrystEngComm, International Journal of Pharmaceutics, Chemical Engineering Journal, etc. Two of these publications have been featured on the front covers of ‘CrystEngComm’ and ‘Chemical Engineering and Technology’. He is also an inventor, with a US patent (US20230111202A1) granted for a nanoparticle generation and isolation technology.
As a reviewer for journal like Powder Technology, CrystEngComm, Crystal Growth & Design, Journal of Molecular Liquids, etc., Dr Verma contributes to the scientific community beyond his own research. He has also mentored early career researchers, including supporting a successful Marie Sklodowska Curie Action's (MSCA) postdoctoral fellowship application. In 2018, he organised the ‘British association of Crystal Growth student day’ conference at the University of Limerick, Ireland.
Dr Verma’s current research focusses developing a platform for the sustainable purification and separation of (bio)pharmaceuticals, alongside exploring secondary processing of (bio)pharmaceuticals and investigating peptide self-assembly for innovative drug delivery technologies.
Research Interests
-Sustainable Purification of (bio)Pharmaceuticals-Peptide Self Assembly
-Crystal Engineering
-Secondary processing of (bio)Pharmaceuticals
-Engineered surfaces
-Lipid nanoparticles
Research Grants
| Project | Funding Body | Start Date | End Date | Award | |
|---|---|---|---|---|---|
| Science Foundation of Ireland | 01-APR-24 | 30-SEP-27 | €564,727.00 | ||
| Soft Template Mediated Peptide Crystallisation (ASPIRATION) | European Commission | 01-SEP-21 | 31-AUG-23 | €224,933.76 |
Publications
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2024) | 'Sequence-dependent dipeptide solubility in ethanol-water and DMSO-water solutions' Liang, Enshu,Verma, Vivek,Guo, Mingxia,Jia, Lihong,Guinn, Emily J.,Heng, Jerry Y.Y. (2024) 'Sequence-dependent dipeptide solubility in ethanol-water and DMSO-water solutions'. Journal of Molecular Liquids, 402 [Details] | |
| (2023) | 'Crystal regeneration – a unique growth phenomenon observed in organic crystals post breakage' Heng, Jerry Y. Y. (2023) 'Crystal regeneration – a unique growth phenomenon observed in organic crystals post breakage'. Materials Horizons, 10 (4):1425-1430 [Details] | |
| (2023) | 'The role of mixing and surface hydrophobicity on the operation of a continuous tubular slug flow crystalliser for lysozyme' Link, Frederik J.,Errington, Ethan,Verma, Vivek,Heng, Jerry Y.Y. (2023) 'The role of mixing and surface hydrophobicity on the operation of a continuous tubular slug flow crystalliser for lysozyme'. Chemical Engineering Journal, 471 [Details] | |
| (2023) | 'Solid solution polymorphs afford two highly soluble co-drug forms of tolbutamide and chlorpropamide' Lusi, Matteo (2023) 'Solid solution polymorphs afford two highly soluble co-drug forms of tolbutamide and chlorpropamide'. Chemical Communications, 59 (96):14321-14324 [Details] | |
| (2023) | 'Templated Crystallization of Glycine Homopeptides: Experimental and Computational Developments' Verma, Vivek,Mitchell, Hamish,Errington, Ethan,Guo, Mingxia,Heng, Jerry Y. Y. (2023) 'Templated Crystallization of Glycine Homopeptides: Experimental and Computational Developments'. Chemical Engineering & Technology, 46 (6):1271-1278 [Details] | |
| (2023) | 'Inclusion Complex of Ibuprofen-ß-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design' Upadhyay, Chandraprabha,D’Souza, Anisha,Patel, Pratikkumar,Verma, Vivek,Upadhayay, Kamal Kumar,Bharkatiya, Meenakshi (2023) 'Inclusion Complex of Ibuprofen-ß-Cyclodextrin Incorporated in Gel for Mucosal Delivery: Optimization Using an Experimental Design'. AAPS PharmSciTech, 24 (4) [Details] | |
| (2023) | 'The Effect of Chain Length and Conformation on the Nucleation of Glycine Homopeptides during the Crystallization Process' Guo, Mingxia,Jones, Marie J.,Goh, Racheal,Verma, Vivek,Guinn, Emily,Heng, Jerry Y. Y. (2023) 'The Effect of Chain Length and Conformation on the Nucleation of Glycine Homopeptides during the Crystallization Process'. Crystal Growth & Design, 23 (3):1668-1675 [Details] | |
| (2023) | 'Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process' Verma, Vivek,Patel, Pratikkumar,Ryan, Kevin M.,Hudson, Sarah,Padrela, Luis (2023) 'Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process'. The Journal of Supercritical Fluids, 192 [Details] | |
| (2022) | 'Solid-state and particle size control of pharmaceutical cocrystals using atomization-based techniques' O'Sullivan, Aaron,Long, Barry,Verma, Vivek,Ryan, Kevin M.,Padrela, Luis (2022) 'Solid-state and particle size control of pharmaceutical cocrystals using atomization-based techniques'. International Journal of Pharmaceutics, 621 [Details] | |
| (2022) | 'The heterogeneous nucleation of pimelic acid under the effect of a template: experimental research and molecular simulation' Heng, Jerry Y. Y. (2022) 'The heterogeneous nucleation of pimelic acid under the effect of a template: experimental research and molecular simulation'. CrystEngComm, 24 (15):2825-2835 [Details] | |
| (2022) | 'The role of the pre-exponential factor in determining the kinetic selection of polymorphs during solution crystallization of organic compounds' Hodnett, Benjamin K. (2022) 'The role of the pre-exponential factor in determining the kinetic selection of polymorphs during solution crystallization of organic compounds'. CrystEngComm, 24 (16):3088-3095 [Details] | |
| (2022) | 'Understanding crystal nucleation mechanisms: where do we stand? General discussion' Zeglinski, Jacek (2022) 'Understanding crystal nucleation mechanisms: where do we stand? General discussion'. Faraday Discussions, 235 (0):219-272 [Details] | |
| (2022) | 'Studying the impact of the pre-exponential factor on templated nucleation' Heng, Jerry Y. Y. (2022) 'Studying the impact of the pre-exponential factor on templated nucleation'. Faraday Discussions, 235 (0):199-218 [Details] | |
| (2022) | 'Controlling the Polymorphism of Indomethacin with Poloxamer 407 in a Gas Antisolvent Crystallization Process' Cañellas, Fidel Méndez,Verma, Vivek,Kujawski, Jacek,Geertman, Robert,Tajber, Lidia,Padrela, Luis (2022) 'Controlling the Polymorphism of Indomethacin with Poloxamer 407 in a Gas Antisolvent Crystallization Process'. ACS Omega, 7 (48):43945-43957 [Details] | |
| (2022) | 'Thermodynamic solubility of celecoxib in organic solvents' Padrela, Luis (2022) 'Thermodynamic solubility of celecoxib in organic solvents'. CrystEngComm, 24 (3):698-710 [Details] | |
| (2022) | 'Balanced lipase interactions for degradation-controlled paclitaxel release from lipid cubic phase formulations' Dully, Michele,Bhattacharya, Shayon,Verma, Vivek,Murray, David,Thompson, Damien,Soulimane, Tewfik,Hudson, Sarah P. (2022) 'Balanced lipase interactions for degradation-controlled paclitaxel release from lipid cubic phase formulations'. Journal of Colloid and Interface Science, 607 :978-991 [Details] | |
| (2021) | 'Ketoprofen Solubility in Pure Organic Solvents Using In Situ FTIR and UV–Vis and Analysis of Solution Thermodynamics' Soto, Rodrigo,Verma, Vivek,Sadeghi, Masoud,Rasmuson, Åke C. (2021) 'Ketoprofen Solubility in Pure Organic Solvents Using In Situ FTIR and UV–Vis and Analysis of Solution Thermodynamics'. Organic Process Research & Development, 25 (11):2403-2414 [Details] | |
| (2021) | 'Needleless electrospun phytochemicals encapsulated nanofibre based 3-ply biodegradable mask for combating COVID-19 pandemic' Patil, Nikhil Avinash,Gore, Prakash Macchindra,Jaya Prakash, Niranjana,Govindaraj, Premika,Yadav, Ramdayal,Verma, Vivek,Shanmugarajan, Dhivya,Patil, Shivanand,Kore, Abhay,Kandasubramanian, Balasubramanian (2021) 'Needleless electrospun phytochemicals encapsulated nanofibre based 3-ply biodegradable mask for combating COVID-19 pandemic'. Chemical Engineering Journal, 416 [Details] | |
| (2021) | 'Generation and physicochemical characterization of posaconazole cocrystals using Gas Antisolvent (GAS) and Supercritical Solvent (CSS) methods' Long, Barry,Verma, Vivek,Ryan, Kevin M.,Padrela, Luis (2021) 'Generation and physicochemical characterization of posaconazole cocrystals using Gas Antisolvent (GAS) and Supercritical Solvent (CSS) methods'. The Journal of Supercritical Fluids, 170 [Details] | |
| (2021) | 'Extended Lifetime of Molecules Adsorbed onto Excipients Drives Nucleation in Heterogeneous Crystallization' Cazade, Pierre-Andre,Verma, Vivek,Hodnett, Benjamin K.,Thompson, Damien (2021) 'Extended Lifetime of Molecules Adsorbed onto Excipients Drives Nucleation in Heterogeneous Crystallization'. Crystal Growth & Design, 21 (4):2101-2112 [Details] | |
| (2021) | 'Pharmaceutical nanoparticle isolation using CO2-assisted dynamic bed coating' Verma, Vivek,Ryan, Kevin M.,Padrela, Luis (2021) 'Pharmaceutical nanoparticle isolation using CO2-assisted dynamic bed coating'. International Journal of Pharmaceutics, 592 [Details] | |
| (2021) | 'Production and isolation of pharmaceutical drug nanoparticles' Verma, Vivek,Ryan, Kevin M.,Padrela, Luis (2021) 'Production and isolation of pharmaceutical drug nanoparticles'. International Journal of Pharmaceutics, 603 [Details] | |
| (2020) | 'Crystal Growth Kinetics of Pharmaceutical Compounds' Soto, Rodrigo,Verma, Vivek,Lynch, Aisling,Hodnett, Benjamin K.,Rasmuson, Åke C. (2020) 'Crystal Growth Kinetics of Pharmaceutical Compounds'. Crystal Growth & Design, 20 (12):7626-7639 [Details] | |
| (2020) | 'Crystal Growth Kinetics of a Metastable Polymorph of Tolbutamide in Organic Solvents' Soto, R.,Verma, V.,Rasmuson, Å. C. (2020) 'Crystal Growth Kinetics of a Metastable Polymorph of Tolbutamide in Organic Solvents'. Crystal Growth & Design, 20 (3):1985-1996 [Details] | |
| (2020) | 'Solubility and thermodynamic analysis of ketoprofen in organic solvents' Soto, Rodrigo,Svärd, Michael,Verma, Vivek,Padrela, Luis,Ryan, Kevin,Rasmuson, Åke C. (2020) 'Solubility and thermodynamic analysis of ketoprofen in organic solvents'. International Journal of Pharmaceutics, 588 [Details] | |
| (2019) | 'Overcoming the Common Ion Effect for Weakly Basic Drugs: Inhibiting the Crystallization of Clofazimine Hydrochloride in Simulated Gastrointestinal Media' Bannigan, Pauric,Verma, Vivek,Hudson, Sarah P. (2019) 'Overcoming the Common Ion Effect for Weakly Basic Drugs: Inhibiting the Crystallization of Clofazimine Hydrochloride in Simulated Gastrointestinal Media'. Crystal Growth & Design, 19 (3):1599-1609 [Details] | |
| (2019) | 'Face indexing and shape analysis of salicylamide crystals grown in different solvents' Rasmuson, Åke (2019) 'Face indexing and shape analysis of salicylamide crystals grown in different solvents'. CrystEngComm, 21 (16):2648-2659 [Details] | |
| (2018) | 'Experimental Study on the Influence of Excipients on the Heterogeneous Crystallization and Dissolution Properties of an Active Pharmaceutical Ingredient' Verma, Vivek,Peddapatla, Raghu V. G.,Crowley, Clare M.,Crean, Abina M.,Davern, Peter,Hudson, Sarah,Hodnett, Benjamin K. (2018) 'Experimental Study on the Influence of Excipients on the Heterogeneous Crystallization and Dissolution Properties of an Active Pharmaceutical Ingredient'. Crystal Growth & Design, 18 (1):338-350 [Details] | |
| (2018) | 'Dependence of Heterogeneous Nucleation on Hydrogen Bonding Lifetime and Complementarity' Verma, Vivek,Zeglinski, Jacek,Hudson, Sarah,Davern, Peter,Hodnett, Benjamin K. (2018) 'Dependence of Heterogeneous Nucleation on Hydrogen Bonding Lifetime and Complementarity'. Crystal Growth & Design, 18 (11):7158-7172 [Details] | |
| (2018) | 'A basis for the kinetic selection of polymorphs during solution crystallization of organic compounds' Hodnett, Benjamin K. (2018) 'A basis for the kinetic selection of polymorphs during solution crystallization of organic compounds'. CrystEngComm, 20 (37):5551-5561 [Details] |
Professional Activities
Honours and Awards
| Year | Title | Awarding Body | |
|---|---|---|---|
| 2024 | Best Presentation at the Annual Post-doc Symposium | Chemical Engineering, Imperial College London, UK | |
| 2022 | Best Poster Prize at the Annual Post-doc Symposium | Chemical Engineering, Imperial College London, UK | |
| 2018 | Annual BOC Postgraduate Prize | Department of Chemical Sciences, the University of Limerick | |
| 2016 | Munster heat winner for all Ireland “Thesis in 3: The Elevator pitch for a PhD” | Thesis in 3: The Elevator pitch for a PhD | |
| 2013 | Summer Research Fellowship | Indian Academy of Sciences (IASc) | |
| 2009 | DST INSPIRE-SHE Fellowship | Government of India |
Patents
| Patent Number | Title | Granted | |
|---|---|---|---|
| US20230111202A1 | Particle Coating Method | 13-APR-23 |
Employment
| Employer | Position | From / To | |
|---|---|---|---|
| University of Limerick | Post-Doctoral Researcher | 15-JAN-19 / 31-MAY-19 | |
| University of Limerick | Post-Doctoral Researcher | 01-JUN-19 / 16-SEP-21 | |
| Imperial College London | Marie Sklodowska Curie Individual Fellow | 01-OCT-21 / 30-APR-24 | |
| University College Cork | Lecturer | 13-MAY-24 / | |
| FMC International, Cork, Ireland | Intern | 01-JUL-17 / 30-SEP-17 |
Education
| Year | Institution | Qualification | Subject | |
|---|---|---|---|---|
| 2018 | University of Limerick | PhD | Pharmaceutical Science | |
| 2014 | Indian Institute of Science Education and Research (IISER), Pune, India | Integrated BS-MS | Chemistry |
Languages
| Language | Reading | Writing | Speaking | |
|---|---|---|---|---|
| English | Fluent | Fluent | Fluent |
Outreach Activities
| Description | |
|---|---|
Imperial Lates, 2023, UK | |
The Great Exhibition Road Festival, 2023, UK |
Journal Activities
| Journal | Role | To / From | |
|---|---|---|---|
| Pharmaceutics | Guest Editor | - | |
| Journal Of Industrial And Engineering Chemistry | Peer Reviewer | - | |
| Crystal Growth & Design | Peer Reviewer | - |
Teaching Activities
Teaching Interests
PE 3009/6009: Pharmaceutical EngineeringPE 1003: Introduction t Process and Chemical Engineering
PE 1813: Fluid Mechanics and Particle Processing
PE 2810: Chemical Engineering Project
Research Information
Internal Collaborators
| Name | Institute | Country | |
|---|---|---|---|
| Professor Abina Crean | University College Cork | IRELAND | |
| Professor Anita Maguire | University College Cork | IRELAND |
External Collaborators
| Name | Organisation / Institute | Country | |
|---|---|---|---|
| Professor Jerry Heng | Imperial College London | UNITED KINGDOM | |
| Dr Abhijit Date | Arizona State University | U.S.A. | |
| Dr Rodrigo Soto | University of Barcelona | SPAIN |