As Director of the BSc (Hons) Physiology and a Senior Lecturer at University College Cork (UCC), Dr Hyland leads interdisciplinary education across the College of Medicine and Health and the College of Science, Engineering, and Food Science (SEFS). His teaching responsibilities include module coordination, lecturing, and supervision across several undergraduate and postgraduate programmes, fostering collaborative learning environments and promoting innovative teaching methodologies.
Module Coordination and Lecturing
PL2034 – Physiology for Dental Students
Role: Coordinator and Lecturer
Credits: 10
Hours: 50
Dr Hyland coordinates and delivers lectures, tutorials, and assessments for this module, providing dental students with a solid foundation in physiology.
PL4015 – Microbiome & Physiology
Role: Coordinator and Lecturer
Credits: 5 Hours: 30
As the first microbiome-focused module at UCC, Dr Hyland designed and coordinates this course, which explores the role of the microbiome in physiology, using a combination of lectures, journal clubs, and student presentations.
PL3025 – Literature Review, Experimental Design, and Data Analysis
Role: Supervisor
Credits: 5
Hours: 20
Dr Hyland supervises students in this module, guiding them through literature reviews and the intricacies of experimental design and data analysis.
PL4020 – Research Project
Role: Coordinator and Supervisor
Credits: 20
Hours: 35
Dr Hyland leads this capstone module, supervising students as they undertake independent research projects, offering mentorship and evaluating their final research output.
MSc Nutrition & Behaviour (Bournemouth University)
Role: Guest Lecturer
Hours: 4
Dr. Hyland is a guest lecturer on this postgraduate course, delivering content on the gut-brain axis and the interaction between nutrition and behaviour.
Pedagogical Innovations and Contributions
Dr Hyland has played a pivotal role in integrating Problem-Based Learning (PBL) into the Graduate Entry to Medicine (GEM) programme, introducing interdisciplinary teaching methods that promote collaborative learning between students. He also led the GEM programme through its first Irish Medical Council accreditation. In his role as Chair of the School of Medicine Athena Swan Working Group, Dr Hyland fosters a culture of inclusivity and belonging, ensuring that the learning environment supports all students.
MINDinGUT Student Mobility Project
Dr Hyland co-led the international MINDinGUT student mobility project, an initiative that attracted over 65 participants from four continents. This project focused on interdisciplinary research and education in gut-brain axis biology, promoting cross-institutional collaboration and offering students hands-on experience in cutting-edge research across borders.
Past Teaching Commitments
Department of Pharmacology, UCC (2008-2018) During his tenure in the Department of Pharmacology at UCC, Dr Hyland held several significant teaching roles, including:
GM1003 – Fundamentals of Medicine III (Graduate Entry to Medicine)
Role: Module Coordinator
Dr Hyland coordinated and delivered lectures for this core module, focusing on the integration of pharmacology into clinical education for graduate-entry medical students.
PT3201 – Dental Pharmacology
Role: Module Coordinator (one academic year)
Dr Hyland developed and delivered a comprehensive pharmacology course tailored specifically for dental students.
PT3445 – Systems Pharmacology
Role: Lecturer
He lectured on systemic pharmacology, providing insights into the effects of drugs on body systems.
Small Group Learning (Case-Based Learning)
Dr Hyland coordinated and facilitated small group learning sessions for Graduate Entry to Medicine students, encouraging the application of theoretical knowledge to practical clinical cases.
University of Calgary (2004-2007)
At the University of Calgary, Dr Hyland taught courses such as:
MDSC 637.01 – Gastrointestinal Physiology
Role: Lecturer
Delivered advanced lectures on gastrointestinal physiology for graduate students, focusing on neurogastroenterology.
MDSC 619.02 – Systems Neuroscience II
Role: Lecturer
Provided in-depth lectures on systems neuroscience with an emphasis on the enteric nervous system.
Thesis Examination and Supervision
Dr Hyland has extensive experience as an external PhD examiner at various institutions, including:
Massey University, New Zealand
University of Melbourne, Australia
Queen Mary University of London, UK
University of Padova, Italy
University of Antwerp, Belgium
He has supervised multiple postgraduate research candidates, guiding their research in areas such as enteric neuroscience and gut-brain interactions.
CPD Contributions and Continuing Medical Education (CME)
Dr Hyland developed the CME course titled "The Gut Microbiome and Diet in Neurogastroenterology: A Guide for the Clinician", accredited by the European Accreditation Council for Continuing Medical Education. This course has provided clinicians with up-to-date knowledge on the gut microbiome and its role in gastrointestinal health. Additionally, he has been selected as Faculty to deliver the upcoming CME course, "Navigating Solutions for DGBI and GI Motility Disorders" at the Federation of Neurogastroenterology and Motility meeting.
Pharmacology Expert Group Curriculum Project
Dr Hyland contributed to the Core Undergraduate Pharmacology Curriculum Project led by the British Pharmacological Society, an expert group initiative aimed at developing a robust pharmacology curriculum for use in quality assurance and programme development. This curriculum has been successfully employed in institutions like Keele University and beyond, ensuring consistency and excellence in pharmacological education.
Additional Teaching Contributions
As Chair of the Graduate Studies Committee (GSC), Dr Hyland oversees the academic progress of postgraduate students, including 10 PhD and three MSc candidates. He is responsible for setting postgraduate teaching and training policies and organizes the annual Physiology Research Day, promoting student research and development. Dr Hyland also participates in mentoring undergraduate students through the SEFS first-year mentoring scheme, supporting their academic growth and career development.
Biography
Dr Niall P. Hyland is a leading academic and researcher specialising in pharmacology, physiology, and the intricate connections between gut microbiota and health. He is a Senior Lecturer in the Department of Physiology at University College Cork (UCC) and plays a vital role as a Funded Investigator at APC Microbiome Ireland, a foremost institution in microbiome research.
Dr Hyland obtained his undergraduate degree in Biomedical Science with honours from the University of Ulster in 2000. He then expanded his research experience internationally through a visiting fellowship at the Louisiana State University Health Sciences Center. His early research interests motivated him to pursue a PhD in Pharmacology at King’s College London, which he completed in 2004. This work laid the groundwork for his ongoing research in neurogastroenterology and gut-brain interactions. Following his doctoral studies, Dr. Hyland undertook a postdoctoral fellowship at the University of Calgary, where he was granted a Research Initiative Award to support his endeavours from the Canadian Association of Gastroenterology, Canadian Institutes of Health Research, and AstraZeneca. In 2007, he returned to Ireland to accept a senior postdoctoral position at APC Microbiome Ireland and joined UCC as a Lecturer in the Department of Pharmacology in 2008, advancing to Senior Lecturer in the Department of Physiology in 2018.
His research primarily investigates the interplay between gut microbiota and the gastrointestinal system in both health and disease, focusing on areas such as Disorders of Gut-Brain Interaction (DGBI), colon cancer, and Fabry Disease. Dr Hyland's laboratory employs advanced methodologies to explore the physiological effects of the microbiome, including probiotics and postbiotics, on gastrointestinal physiology and drug-gut microbiome interactions. His notable contributions encompass research on the physiological effects of gut microbes, gastrointestinal complications related to stress, and real-time monitoring of neural activity in the gut. He has co-edited two editions of The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, published by Academic Press, and maintains an H-index of 31, reflecting his significant impact in the field. With numerous publications in respected peer-reviewed journals and over €3 million secured in research funding, Dr Hyland's expertise is widely recognised.
In addition to his academic pursuits, Dr Hyland is actively engaged in various professional organisations. He has served as Vice President of Meetings for the British Pharmacological Society and has contributed to steering committees within European and American gastroenterological associations. His editorial roles include a Senior Editorship at Pharmacology Research & Perspectives, an Open Access journal of the British Pharmacological Society and the American Society for Pharmacology and Experimental Therapeutics, and acting as a review editor for several key journals in neuroscience and physiology.
In 2022, Dr Hyland was honored with an Honorary Fellowship from the British Pharmacological Society in recognition of his significant contributions.
Dr Hyland obtained his undergraduate degree in Biomedical Science with honours from the University of Ulster in 2000. He then expanded his research experience internationally through a visiting fellowship at the Louisiana State University Health Sciences Center. His early research interests motivated him to pursue a PhD in Pharmacology at King’s College London, which he completed in 2004. This work laid the groundwork for his ongoing research in neurogastroenterology and gut-brain interactions. Following his doctoral studies, Dr. Hyland undertook a postdoctoral fellowship at the University of Calgary, where he was granted a Research Initiative Award to support his endeavours from the Canadian Association of Gastroenterology, Canadian Institutes of Health Research, and AstraZeneca. In 2007, he returned to Ireland to accept a senior postdoctoral position at APC Microbiome Ireland and joined UCC as a Lecturer in the Department of Pharmacology in 2008, advancing to Senior Lecturer in the Department of Physiology in 2018.
His research primarily investigates the interplay between gut microbiota and the gastrointestinal system in both health and disease, focusing on areas such as Disorders of Gut-Brain Interaction (DGBI), colon cancer, and Fabry Disease. Dr Hyland's laboratory employs advanced methodologies to explore the physiological effects of the microbiome, including probiotics and postbiotics, on gastrointestinal physiology and drug-gut microbiome interactions. His notable contributions encompass research on the physiological effects of gut microbes, gastrointestinal complications related to stress, and real-time monitoring of neural activity in the gut. He has co-edited two editions of The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, published by Academic Press, and maintains an H-index of 31, reflecting his significant impact in the field. With numerous publications in respected peer-reviewed journals and over €3 million secured in research funding, Dr Hyland's expertise is widely recognised.
In addition to his academic pursuits, Dr Hyland is actively engaged in various professional organisations. He has served as Vice President of Meetings for the British Pharmacological Society and has contributed to steering committees within European and American gastroenterological associations. His editorial roles include a Senior Editorship at Pharmacology Research & Perspectives, an Open Access journal of the British Pharmacological Society and the American Society for Pharmacology and Experimental Therapeutics, and acting as a review editor for several key journals in neuroscience and physiology.
In 2022, Dr Hyland was honored with an Honorary Fellowship from the British Pharmacological Society in recognition of his significant contributions.
Research Interests
Dr Hyland’s research laboratory employs a multidisciplinary approach, utilising advanced ex vivo techniques such as Ussing chambers and organ bath preparations, alongside in vitro models like Caco-2 monolayers, and in vivo disease models focused on stress and colon cancer. His collaboration with the University of Cambridge on implantable bioelectronics for real-time monitoring of enteric neural activity exemplifies his pioneering research. A significant area of focus involves examining the effects of microbial-targeted interventions, including probiotics and postbiotics, on gut health, as well as delineating microbiome signatures associated with colon cancer. With over 8,336 citations and an H-index of 31, Dr Hyland has extensively published on the gut-brain axis and microbiome-host interactions. His research has garnered substantial funding exceeding €3.3 million from industry as well as Irish and EU funding agencies.
Dr Hyland's work consistently emphasises the pharmacological and therapeutic potential of the gut microbiota. His investigations address critical questions regarding how modulating the microbiome can enhance gastrointestinal health, alleviate stress-related disorders, and improve drug efficacy. His research traverses several interconnected fields, including gut-brain axis studies, microbiome-host dynamics, drug metabolism, and gastrointestinal disorders.
Gut-Brain Axis and Microbiome
Dr Hyland’s contributions to the understanding of the gut-brain axis are vital to his research endeavours. He also explores the effects of stress on gastrointestinal physiology, particularly within the framework of the gut-brain axis.
Microbiota-Drug Interactions
A key dimension of Dr Hyland’s research is the investigation of how gut microbiota interact with pharmaceutical medications.
Microbial Interventions and Gut Health
Dr Hyland’s research facilitates the development of innovative gut health therapies targeting the microbiome to modulate intestinal physiology.
Colon Cancer and Microbiome
In collaboration with colleagues, Dr Hyland has examined the role of the microbiome in the development of colon cancer. His research underscores the potential for targeting microbiota-related pathways in cancer therapies.
Dr Hyland's work consistently emphasises the pharmacological and therapeutic potential of the gut microbiota. His investigations address critical questions regarding how modulating the microbiome can enhance gastrointestinal health, alleviate stress-related disorders, and improve drug efficacy. His research traverses several interconnected fields, including gut-brain axis studies, microbiome-host dynamics, drug metabolism, and gastrointestinal disorders.
Gut-Brain Axis and Microbiome
Dr Hyland’s contributions to the understanding of the gut-brain axis are vital to his research endeavours. He also explores the effects of stress on gastrointestinal physiology, particularly within the framework of the gut-brain axis.
Microbiota-Drug Interactions
A key dimension of Dr Hyland’s research is the investigation of how gut microbiota interact with pharmaceutical medications.
Microbial Interventions and Gut Health
Dr Hyland’s research facilitates the development of innovative gut health therapies targeting the microbiome to modulate intestinal physiology.
Colon Cancer and Microbiome
In collaboration with colleagues, Dr Hyland has examined the role of the microbiome in the development of colon cancer. His research underscores the potential for targeting microbiota-related pathways in cancer therapies.
Research Grants
| Project | Funding Body | Start Date | End Date | Award | |
|---|---|---|---|---|---|
| Chacterisation of Ingredients and Beverages on Gut Hormone Signalling and Intestinal Ion Transport | Foreign Industry | 05-JAN-25 | 03-JAN-27 | €409,330.00 | |
| GO-AHEAD - Gastrointestinal Oxytocin is importAnt in HEalth And Disease (Co-mentor/ Collaborator/ PhD student Co-supervisor) | Science Foundation Ireland | 01-SEP-23 | 02-SEP-27 | €436,073.00 | |
| Unravelling the Relationship Between Early Life Gut Microbiome Establishment and Gastrointestinal Dysfunction in Autism SpecTrum DisordEr - RELATE | Horizon 2020 | 02-SEP-24 | 01-SEP-26 | €142,348.00 | |
| Assessment of Bacterial Strains for Functional and Psychobiotic Properties and their Impact on Gut-Brain Axis Health Outcomes | Foreign Industry | 01-MAR-24 | 02-MAR-26 | €596,292.00 | |
| Global Grant for Gut Health Annual Grant | 25-OCT-23 | 24-OCT-25 | €7,344.00 | ||
| Candidate Psychobiotics and Alterations in Microbiome-Gut-Brain Axis Signalling Pathways | Foreign Industry | 11-JUL-21 | 30-JUN-23 | €505,071.00 | |
| enTeRic Afferent seNsing to aScribe MIcrobial activity (TRANSMIT) | Horizon 2020 | 28-JAN-22 | 31-JAN-23 | €123,840.00 | |
| HEA COVID-19 Support | Higher Education Authority (HEA) | 27-JUL-22 | 28-SEP-22 | €7,820.00 | |
| Impact of the Gut Microbiota on Early Life Structural Development of the Vagus Nerve and Vagal Signalling | Irish Research Council | €96,000.00 | |||
| Drug‐Gut Microbiota Interactions: Developing a Pathway to Personalised Medicine in Psychiatry (Global Grants for Gut Health) | Other: Not Listed | 25-MAR-19 | 31-DEC-20 | €98,046.00 | |
| The Gut Microbiome and Systems Pharmacology: Establishing a Platform for Screening Bacterial Xenobiotic Metabolism (APC Innovation Platform under SFI/12/RC/2273) | Science Foundation Ireland | 01-SEP-16 | 30-SEP-19 | €118,000.00 | |
| Evaluation of the Bioavailability, Absorption and Effects on Intestinal Permeability of a Multi-Mineral Natural Product, Aquamin | Irish Research Council | 04-JAN-16 | 31-JAN-18 | €91,790.00 | |
| Supplemental Consumable Support from Marigot Ltd for IRC EPS EPSPD/2015/52 | Industry Sponsor | 01-FEB-16 | 03-JAN-18 | €15,000.00 | |
| Characterisation of the Bladder Microbiota and Urothelium in Bladder Pain Syndrome: Lessons from Irritable Bowel Syndrome (APC Innovation Platform under SFI/12/RC/2273) | Science Foundation Ireland | 01-OCT-16 | 28-SEP-18 | €78,500.00 | |
| The Microbiota and Colon Cancer Risk (APC Innovation Platform under SFI/12/RC/2273) | Science Foundation Ireland | 01-OCT-14 | 28-SEP-18 | €158,000.00 | |
| NeuroGASTRO 2017 SFI Conference and Workshop Grant | Science Foundation Ireland | 27-JUN-17 | 26-AUG-17 | €30,570.00 | |
| Validation of Intestinal Tryptophan Metabolism as a Therapeutic Target in Obesity and Insulin Resistance (SFI Industry Fellowship Programme) | Science Foundation Ireland | 01-JUN-16 | 30-NOV-16 | €14,145.00 | |
| Enterprise Ireland H2020 Travel Support to Establish the H2020 Consortium 'sENS4life' and submission of the proposal 'The role of the Enteric Nervous System in Functional GastroIntestinal Disorders and its Comorbidities' | Enterprise Ireland | 05-MAR-15 | 05-SEP-15 | €650.00 | |
| Mast Cell Subtypes in Patients with Irritable Bowel Syndrom; Are Connective Tissue Mast Cells and Chymase Valid Therapeutic Targets? | Health Research Board | 01-DEC-11 | 03-JAN-14 | €173,897.00 | |
| Examination of the Small Intestinal Transport of Aquamin-derived Calcium Under High and Low Calcium Conditions in Ussing Chambers | Industry Sponsor | 31-OCT-13 | 30-SEP-14 | €9,315.00 | |
| Evaluation of Intestinal and Colonic Transport of Aquamin-derived Calcium in Ussing Chambers | Industry Sponsor | 15-JUL-13 | 11-DEC-13 | €2,570.00 | |
| Enteroendocrine Peptides as Mediators of Diet-Induced Obesity (Canadian Association of Gastroenterology CAG/CIHR AstraZeneca Research Initiative Award) | Other: Not Listed | €74,555.00 |
Contract Researchers
| Researcher Name | Project | Role | Funding Body | |
|---|---|---|---|---|
| Dr Alexander Putra Kanon (current) | Industry-funded projects | Project Manager | Industry Sponsor | |
| Dr Friederike Uhlig (2023-2027; SFI_IRC Pathways Fellow) | GO-AHEAD 'Gastrointestinal Oxytocin is importAnt in HEalth And Disease' | Research Fellow | Science Foundation Ireland | |
| Dr Morgane LeDrean (2024-2026) | Unravelling the Relationship Between Early Life Gut Microbiome Establishment and Gastrointestinal Dysfunction in Autism SpecTrum DisordEr (RELATE) | Postdoctoral Researcher | Horizon 2020 | |
| Dr Camila Barrera (2024-2026) | Assessment of Bacterial Strains for Functional and Psychobiotic Properties and their Impact on Gut-Brain Axis Health Outcomes | Postdoctoral Researcher | Industry Sponsor | |
| Dr Friederike Uhlig (Currently, SFI-IRC Pathways Fellow) | enTeRic Afferent seNsing to aScribe MIcrobial activity (TRANSMIT) | Postdoctoral Researcher | Horizon 2020 | |
| Dr Klara Vlckova (Currently, Research Scientist at Fonterra Microbiome Research Centre (Ireland)) | Candidate Psychobiotics and Alterations in Microbiome-Gut-Brain Axis Signalling Pathways | Postdoctoral Researcher | Industry Sponsor | |
| Dr Thaísa Barros Dos Santos (Currently, Senior Associate - Global Scientific Communications Eli Lilly and Company) | Candidate Psychobiotics and Alterations in Microbiome-Gut-Brain Axis Signalling Pathways | Research Assistant | Industry Sponsor | |
| Dr Jonathan Keane (Currently, Postdoctoral Researcher, School of Microbiology, UCC) | Drug‐Gut Microbiota Interactions: Developing a Pathway to Personalised Medicine in Psychiatry (Global Grants for Gut Health) | Research Assistant | Other: Not Listed | |
| Ms. Olivia Artaiz (Currently, Research Assistant, University of Melbourne, Australia) | Drug‐Gut Microbiota Interactions: Developing a Pathway to Personalised Medicine in Psychiatry (Global Grants for Gut Health) | Research Assistant | Other: Not Listed | |
| Dr Valeria Felice (Currently, Lead Researcher at H&H Group) | Evaluation of the Bioavailability, Absorption and Effects on Intestinal Permeability of a Multi-Mineral Natural Product, Aquamin | Postdoctoral Researcher | Irish Research Council | |
| Dr Sinead Heuston (Currently, Technical Services/Manufacturing Science Representative at Eli Lilly and Company) | Mast Cell Subtypes in Patients with Irritable Bowel Syndrom; Are Connective Tissue Mast Cells and Chymase Valid Therapeutic Targets? | Postdoctoral Researcher | Health Research Board | |
| Dr Barbara Doerr (Currently, Scientist/Toxicologist/Risk Assessor at Food Standards Agency, UK) | Quantitative Analysis of Mucosal Oxygenation Using Ex Vivo Imaging of Healthy and Inflamed Mammalian Colon Tissue | Research Assistant | Enterprise Ireland |
Publications
Edited Books
| Year | Publication | |
|---|---|---|
| (2023) | The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota (2nd Edition) Niall Hyland,Catherine Stanton (Ed.). (2023) The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota (2nd Edition) London, United Kingdom: Academic Press. [Details] | |
| (2016) | The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota (1st Edition) Niall Hyland & Catherine Stanton (Ed.). (2016) The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota (1st Edition) Oxford, UK: Academic Press. [Details] |
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2024) | 'Characterization of Fabry disease-associated lyso-Gb3 on mouse colonic ion transport and motility' Delprete C;Uhlig F;Caprini M;Hyland NP; (2024) 'Characterization of Fabry disease-associated lyso-Gb3 on mouse colonic ion transport and motility'. American Journal of Physiology - Gastrointestinal and Liver Physiology, [DOI] [Details] | |
| (2024) | 'Interplay between microbial-derived GABA and host GABA receptor signaling collectively influence the tumorigenic function of GABA in colon cancer' Keane JM;Fernandes P;Kratz F;O'Callaghan G;Gahan CGM;Joyce SA;Stanton C;Hyland NP;Houston A; (2024) 'Interplay between microbial-derived GABA and host GABA receptor signaling collectively influence the tumorigenic function of GABA in colon cancer'. Pharmacology Research & Perspectives, 12 (4) [DOI] [Details] | |
| (2023) | 'Engraftment of aging-related human gut microbiota and the effect of a seven-species consortium in a pre-clinical model' Ye H;Ghosh TS;Hueston CM;Vlckova K;Golubeva AV;Hyland NP;O'Toole PW; (2023) 'Engraftment of aging-related human gut microbiota and the effect of a seven-species consortium in a pre-clinical model'. Gut microbes, 15 (2) [DOI] [Details] | |
| (2023) | 'Disruption of the microbiota-gut-brain axis is a defining characteristic of the a-Gal A (-/0) mouse model of Fabry disease' Delprete C;Rimondini Giorgini R;Lucarini E;Bastiaanssen TFS;Scicchitano D;Interino N;Formaggio F;Uhlig F;Ghelardini C;Hyland NP;Cryan JF;Liguori R;Candela M;Fiori J;Turroni S;Di Cesare Mannelli L;Caprini M; (2023) 'Disruption of the microbiota-gut-brain axis is a defining characteristic of the a-Gal A (-/0) mouse model of Fabry disease'. Gut microbes, 15 (2) [DOI] [Details] | |
| (2023) | 'The impact of acute and chronic stress on gastrointestinal physiology and function: a microbiota-gut-brain axis perspective' Leigh SJ;Uhlig F;Wilmes L;Sanchez-Diaz P;Gheorghe CE;Goodson MS;Kelley-Loughnane N;Hyland NP;Cryan JF;Clarke G; (2023) 'The impact of acute and chronic stress on gastrointestinal physiology and function: a microbiota-gut-brain axis perspective'. Journal of Physiology-London, 601 (20) [DOI] [Details] | |
| (2023) | 'Beta 3-adrenoceptor agonism ameliorates early-life stress-induced visceral hypersensitivity in male rats' Collins JM;Hyland NP;Clarke G;Fitzgerald P;Julio-Pieper M;Bulmer DC;Dinan TG;Cryan JF;O'Mahony SM; (2023) 'Beta 3-adrenoceptor agonism ameliorates early-life stress-induced visceral hypersensitivity in male rats'. Journal of Neurochemistry, [DOI] [Details] | |
| (2023) | 'Physiological bioactivity of a postbiotic consisting of heat-treated lactobacilli on mouse small intestine' Uhlig F.;Warda A.K.;Hueston C.M.;Draper L.A.;Chauvière G.;Eckhardt E.;Hill C.;Hyland N.P. (2023) 'Physiological bioactivity of a postbiotic consisting of heat-treated lactobacilli on mouse small intestine'. Journal Of Functional Foods, 108 [DOI] [Details] | |
| (2023) | 'The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress' Lobo B;Tramullas M;Finger BC;Lomasney KW;Beltran C;Clarke G;Santos J;Hyland NP;Dinan TG;Cryan JF; (2023) 'The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress'. Neuro-Gastroenterology and Motility, 29 (1) [DOI] [Details] | |
| (2023) | 'Microbes, oxytocin and stress: Converging players regulating eating behavior' Cuesta-Marti C;Uhlig F;Muguerza B;Hyland N;Clarke G;Schellekens H; (2023) 'Microbes, oxytocin and stress: Converging players regulating eating behavior'. Journal of Neuroendocrinology, [DOI] [Details] | |
| (2022) | 'Making Sense of Quorum Sensing at the Intestinal Mucosal Interface' Uhlig, F;Hyland, NP (2022) 'Making Sense of Quorum Sensing at the Intestinal Mucosal Interface'. Cells, 11 [DOI] [Details] | |
| (2022) | 'Investigation of the gut microbiome, bile acid composition and host immunoinflammatory response in a model of azoxymethane-induced colon cancer at discrete timepoints' Keane, JM;Walsh, CJ;Cronin, P;Baker, K;Melgar, S;Cotter, PD;Joyce, SA;Gahan, CGM;Houston, A;Hyland, NP (2022) 'Investigation of the gut microbiome, bile acid composition and host immunoinflammatory response in a model of azoxymethane-induced colon cancer at discrete timepoints'. British Journal of Cancer, [DOI] [Details] | |
| (2022) | 'Emerging effects of tryptophan pathway metabolites and intestinal microbiota on metabolism and intestinal function' Hyland, NP;Cavanaugh, CR;Hornby, PJ (2022) 'Emerging effects of tryptophan pathway metabolites and intestinal microbiota on metabolism and intestinal function'. Amino Acids, [DOI] [Full Text] [Details] | |
| (2021) | 'The gut microbiome influences the bioavailability of olanzapine in rats' Cussotto, Sofia; Walsh, Jacinta; Golubeva, Anna V.; Zhdanov, Alexander V.; Strain, Conall R.; Fouhy, Fiona; Stanton, Catherine; Dinan, Timothy G.; Hyland, Niall P.; Clarke, Gerard; Cryan, John F.; Griffin, Brendan T. (2021) 'The gut microbiome influences the bioavailability of olanzapine in rats'. Ebiomedicine, 66 [DOI] [Full Text] [Details] | |
| (2020) | 'A Marine-Derived, Multi-mineral Supplement Influences Bacterial Fermentation and Short Chain Fatty Acid ProfileIn Vitro' Felice, VD;O'Gorman, DM;Apajalahti, J;Rinttila, T;O'Brien, NM;Hyland, NP (2020) 'A Marine-Derived, Multi-mineral Supplement Influences Bacterial Fermentation and Short Chain Fatty Acid ProfileIn Vitro'. Journal Of Medicinal Food, [DOI] [Details] | |
| (2020) | 'Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin' Walsh, J;Gheorghe, CE;Lyte, JM;van de Wouw, M;Boehme, M;Dinan, TG;Cryan, JF;Griffin, BT;Clarke, G;Hyland, NP (2020) 'Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin'. Journal of Pharmacy and Pharmacology, [DOI] [Details] | |
| (2020) | 'Nigral overexpression of alpha-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome' O'Donovan, SM;Crowley, EK;Brown, JRM;O'Sullivan, O;O'Leary, OF;Timmons, S;Nolan, YM;Clarke, DJ;Hyland, NP;Joyce, SA;Sullivan, AM;O'Neill, C (2020) 'Nigral overexpression of alpha-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome'. Neurogastroenterology and Motility, 32 [DOI] [Details] | |
| (2020) | 'Impact of host and environmental factors on ß-glucuronidase enzymatic activity: implications for gastrointestinal serotonin' Walsh, Jacinta; Olavarria-Ramirez, Loreto; Lach, Gilliard; Boehme, Marcus; Dinan, Timothy G.; Cryan, John F.; Griffin, Brendan T.; Hyland, Niall P.; Clarke, Gerard (2020) 'Impact of host and environmental factors on ß-glucuronidase enzymatic activity: implications for gastrointestinal serotonin'. American Journal of Physiology - Gastrointestinal and Liver Physiology, [DOI] [Full Text] [Details] | |
| (2019) | 'The Microbiota-Gut-Brain Axis' Cryan J.;O'Riordan K.;Cowan C.;Sandhu K.;Bastiaanssen T.;Boehme M.;Codagnone M.;Cussotto S.;Fulling C.;Golubeva A.;Guzzetta K.;Jaggar M.;Long-Smith C.;Lyte J.;Martin J.;Molinero-Perez A.;Moloney G.;Morelli E.;Morillas E.;O'Connor R.;Cruz-Pereira J.;Peterson V.;Rea K.;Ritz N.;Sherwin E.;Spichak S.;Teichman E.;van de Wouw M.;Ventura-Silva A.;Wallace-Fitzsimons S.;Hyland N.;Clarke G.;Dinan T. (2019) 'The Microbiota-Gut-Brain Axis'. Physiological reviews, 99 (4):1877-2013 [DOI] [Full Text] [Details] | |
| (2019) | 'Gut Reactions: Breaking Down Xenobiotic-Microbiome Interactions' Clarke G;Sandhu KV;Griffin BT;Dinan TG;Cryan JF;Hyland NP; (2019) 'Gut Reactions: Breaking Down Xenobiotic-Microbiome Interactions'. Pharmacological reviews, 71 (2) [DOI] [Full Text] [Details] | |
| (2018) | 'When pharmacology meets the microbiome: new targets for therapeutics?' Hyland, Niall P.; Cryan, John F. (2018) 'When pharmacology meets the microbiome: new targets for therapeutics?'. British journal of pharmacology, 175 (24):4401-4403 [DOI] [Full Text] [Details] | |
| (2018) | 'Drug-gut microbiota interactions: implications for neuropharmacology' Walsh, Jacinta; Griffin, Brendan T.; Clarke, Gerard; Hyland, Niall P. (2018) 'Drug-gut microbiota interactions: implications for neuropharmacology'. British journal of pharmacology, [DOI] [Full Text] [Details] | |
| (2018) | 'Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium' Felice VD, O'Gorman DM, O'Brien NM, Hyland N (2018) 'Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium'. Nutrients, 10 (7) [DOI] [Details] | |
| (2017) | 'Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism' Golubeva AV;Joyce SA;Moloney G;Burokas A;Sherwin E;Arboleya S;Flynn I;Khochanskiy D;Moya-Pérez A;Peterson V;Rea K;Murphy K;Makarova O;Buravkov S;Hyland NP;Stanton C;Clarke G;Gahan CGM;Dinan TG;Cryan JF; (2017) 'Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism'. Ebiomedicine, 24 [DOI] [Details] | |
| (2016) | 'Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue' Zhdanov AV;Okkelman IA;Golubeva AV;Doerr B;Hyland NP;Melgar S;Shanahan F;Cryan JF;Papkovsky DB; (2016) 'Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue'. Cellular and Molecular Life Sciences, [DOI] [Details] | |
| (2016) | 'Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system' Hyland NP;Cryan JF; (2016) 'Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system'. Developmental Biology, [DOI] [Details] | |
| (2015) | 'Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders' Kelly JR;Kennedy PJ;Cryan JF;Dinan TG;Clarke G;Hyland NP; (2015) 'Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders'. Frontiers in Cellular Neuroscience, 9 [DOI] [Details] | |
| (2015) | 'Prenatal Stress Induces Subtle Alterations in Major Physiological Systems: a Role for Gut Microbiota?' Golubeva AV, Crampton S, Desbonnet L, Edge D, O’Sullivan O, Lomasney KW, Zhdanov AV, Moloney RD, Borre YE, Cotter PD, Hyland NP, O'Halloran KD, Dinan TG, O’Keeffe GW #, Cryan JF#. (2015) 'Prenatal Stress Induces Subtle Alterations in Major Physiological Systems: a Role for Gut Microbiota?'. Psychoneuroendocrinology, 60 :58-75 [Details] | |
| (2014) | 'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain–gut axis dysfunction' N. P. Hyland, S. M. O'Mahony, D. O'Malley, C. M. O'Mahony, T. G. Dinan and J. F. Cryan. (2014) 'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain–gut axis dysfunction'. Neurogastroenterol & Motility, [DOI] [Details] | |
| (2014) | 'Microbiota-host interactions in irritable bowel syndrome: epithelial barrier, immune regulation and brain-gut interactions' Hyland NP, Quigley EM, Brint E (2014) 'Microbiota-host interactions in irritable bowel syndrome: epithelial barrier, immune regulation and brain-gut interactions'. World journal of gastroenterology : WJG, 20 (27):8859-8866 [DOI] [Details] | |
| (2014) | 'GABAB receptors in the bladder and bowel: Therapeutic potential for positive allosteric modulators?' Hyland NP, Golubeva AV (2014) 'GABAB receptors in the bladder and bowel: Therapeutic potential for positive allosteric modulators?'. British journal of pharmacology, [DOI] [Details] | |
| (2014) | 'Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats' O'Mahony SM, Felice VD, Nally K, Savignac HM, Claesson MJ, Scully P, Woznicki J, Hyland NP, Shanahan F, Quigley EM, Marchesi JR, O'Toole PW, Dinan TG, Cryan JF (2014) 'Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats'. Neuroscience, 277C :885-901 [DOI] [Details] | |
| (2014) | 'Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology' Lomasney, KW,Cryan, JF,Hyland, NP (2014) 'Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology'. American Journal Of Physiology-Gastrointestinal And Liver Physiology, 307 :241-247 [DOI] [Details] | |
| (2013) | 'Disodium Cromoglycate Reverses Colonic Visceral Hypersensitivity and Influences Colonic Ion Transport in a Stress-Sensitive Rat Strain' Carroll, SY,O'Mahony, SM,Grenham, S,Cryan, JF,Hyland, NP (2013) 'Disodium Cromoglycate Reverses Colonic Visceral Hypersensitivity and Influences Colonic Ion Transport in a Stress-Sensitive Rat Strain'. Plos One, 8 [DOI] [Full Text] [Details] | |
| (2013) | 'The application of Ussing chambers for determining the impact of microbes and probiotics on intestinal ion transport' Lomasney KW, Hyland NP (2013) 'The application of Ussing chambers for determining the impact of microbes and probiotics on intestinal ion transport'. Canadian Journal of Physiology and Pharmacology, 91 (9):663-670 [DOI] [Details] | |
| (2012) | 'Chymase inhibition as a pharmacological target: A role in inflammatory and functional gastrointestinal disorders?' Heuston S, Hyland NP (2012) 'Chymase inhibition as a pharmacological target: A role in inflammatory and functional gastrointestinal disorders?'. British Journal of Pharmacology, [DOI] [Details] | |
| (2011) | 'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain' Savignac, HM,Hyland, NP,Dinan, TG,Cryan, JF; (2011) 'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain'. Behavioural Brain Research, 216 :576-584 [DOI] [Details] | |
| (2011) | 'Functional Dyspepsia-Another Red State! Eosinophils, MacRophages, and Postinfectious Dyspepsia' Craig OF, Hyland NP, Quigley EM; (2011) 'Functional Dyspepsia-Another Red State! Eosinophils, MacRophages, and Postinfectious Dyspepsia'. Gastroenterology, [DOI] [Details] | |
| (2011) | 'Maternal separation as a model of brain-gut axis dysfunction' O'Mahony, SM; Hyland, NP; Dinan, TG; Cryan, JF; (2011) 'Maternal separation as a model of brain-gut axis dysfunction'. Psychopharmacology, [DOI] [Details] | |
| (2010) | 'Adaptation of intestinal secretomotor function and nutrient absorption in response to diet-induced obesity' Hyland, NP,Rybicka, JM,Ho, W,Pittman, QJ,Macnaughton, WK,Sharkey, KA; (2010) 'Adaptation of intestinal secretomotor function and nutrient absorption in response to diet-induced obesity'. Neurogastroenterology and Motility, 22 [DOI] [Details] | |
| (2010) | 'A Gut Feeling about GABA: Focus on GABA(B) Receptors' Hyland NP and Cryan JF (2010) 'A Gut Feeling about GABA: Focus on GABA(B) Receptors'. Frontiers In Pharmacology, [DOI] [Details] | |
| (2009) | 'A Mouse Model for Visualization of GABA(B) Receptors' Casanova, E,Guetg, N,Vigot, R,Seddik, R,Julio-Pieper, M,Hyland, NP,Cryan, JF,Gassmann, M,Bettler, B; (2009) 'A Mouse Model for Visualization of GABA(B) Receptors'. Genesis, 47 :595-602 [DOI] [Details] | |
| (2009) | 'A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity?' Hyland NP, Julio-Pieper M, O'Mahony SM, Bulmer DC, Lee K, Quigley EM, Dinan TG, Cryan JF; (2009) 'A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity?'. Gut, 58 (7):1029-101 [DOI] [Details] | |
| (2009) | 'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome' McKernan, DP,Nolan, A,Brint, EK,O'Mahony, SM,Hyland, NP,Cryan, JF,Dinan, TG; (2009) 'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome'. Plos One, 4 [DOI] [Details] | |
| (2009) | 'Differential adipokine response in genetically-predisposed lean and obese rats during inflammation; a role in modulating experimental colitis?' Hyland NP, Chambers AP, Keenan CM, Pittman QJ, Sharkey KA; (2009) 'Differential adipokine response in genetically-predisposed lean and obese rats during inflammation; a role in modulating experimental colitis?'. American Journal of Physiology - Gastrointestinal and Liver Physiology, [DOI] [Details] | |
| (2007) | 'Neonatal immune challenge exacerbates experimental colitis in adult rats: potential role for TNF-alpha' Spencer SJ, Hyland NP, Sharkey KA, Pittman QJ; (2007) 'Neonatal immune challenge exacerbates experimental colitis in adult rats: potential role for TNF-alpha'. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 292 (1):1-15 [DOI] [Details] | |
| (2007) | 'Peptide YY containing enteroendocrine cells and peripheral tissue sensitivity to PYY and PYY(3-36) are maintained in diet-induced obese and diet-resistant rats' Hyland NP, Pittman QJ, Sharkey KA; (2007) 'Peptide YY containing enteroendocrine cells and peripheral tissue sensitivity to PYY and PYY(3-36) are maintained in diet-induced obese and diet-resistant rats'. Peptides, 28 (6):1185-1190 [DOI] [Details] | |
| (2006) | 'Persistent alterations to enteric neural signalling in the colon following resolution of colitis' *Lomax AE, *O'Hara JR, *Hyland NP, Mawe GM, Sharkey KA. ; (2006) 'Persistent alterations to enteric neural signalling in the colon following resolution of colitis'. American journal of physiology. Gastrointestinal and liver physiology, 292 (2):G282-491 [Details] | |
| (2005) | 'The regulation of veratridine-stimulated electrogenic ion transport in mouse colon by neuropeptide Y (NPY), Y1 and Y2 receptors' Hyland NP and Cox HM. ; (2005) 'The regulation of veratridine-stimulated electrogenic ion transport in mouse colon by neuropeptide Y (NPY), Y1 and Y2 receptors'. British Journal of Pharmacology, 146 (5):712-722 [Details] | |
| (2003) | 'Functional consequences of neuropeptide Y Y2 receptor knockout and Y2 antagonism in mouse and human colonic tissues' Hyland NP, Sjöberg F, Tough IR, Herzog H, Cox HM. ; (2003) 'Functional consequences of neuropeptide Y Y2 receptor knockout and Y2 antagonism in mouse and human colonic tissues'. British Journal of Pharmacology, 139 (4):863-871 [Details] | |
| (2001) | 'Site of action of GABA(B) receptor for vagal motor control of the lower esophageal sphincter in ferrets and rats' McDermott CM, Abrahams TP, Partosoedarso E, Hyland N, Ekstrand J, Monroe M, Hornby PJ. ; (2001) 'Site of action of GABA(B) receptor for vagal motor control of the lower esophageal sphincter in ferrets and rats'. Gastroenterology, 120 (7):1749-1762 [Details] | |
| (2001) | 'Organization and neurochemistry of vagal preganglionic neurons innervating the lower esophageal sphincter in ferrets' Hyland NP, Abrahams TP, Fuchs K, et al. ; (2001) 'Organization and neurochemistry of vagal preganglionic neurons innervating the lower esophageal sphincter in ferrets'. Journal of Comparative Neurology, 430 (2):222-234 [Details] |
Other Journals
| Year | Publication | |
|---|---|---|
| (2024) | 'Implantable Bioelectronics for Real-time in vivo Recordings of Enteric Neural Activity' Boys, Alexander J. and Guemes, Amparo and Gupta, Rohit A. and Uhlig, Friederike H. and Hyland, Niall P. and Bulmer, David C. and Malliaras, George G. and Owens, Roisin M. (2024) 'Implantable Bioelectronics for Real-time in vivo Recordings of Enteric Neural Activity' Biorxiv, . [DOI] [Details] |
Book Chapters
| Year | Publication | |
|---|---|---|
| (2020) | 'Microbial metabolites as molecular mediators of host-microbe symbiosis in colorectal cancer' Keane, Jonathan M.; Joyce, Susan A.; Gahan, Cormac G. M.; Hyland, Niall P.; Houston, Aileen (2020) 'Microbial metabolites as molecular mediators of host-microbe symbiosis in colorectal cancer' In: Results And Problems In Cell Differentiation. Cham, Switzerland: Springer. [DOI] [Full Text] [Details] | |
| (2004) | 'NPY-like peptides, Y receptors and gastrointestinal function' Hyland NP and Cox HM. ; (2004) 'NPY-like peptides, Y receptors and gastrointestinal function' In: Michel MC, ed. Handbook of experimental pharmacology: NPY and related peptides. Heidelberg: Springer. [Details] |
Conference Publications
| Year | Publication | |
|---|---|---|
| (2023) | NeuroGASTRO 2023 Uhlig, F. and Hyland, N. (2023) Differential apical-basolateral sensitivity to short chain fatty acids in mouse small intestine and colon NeuroGASTRO 2023 [Details] | |
| (2022) | 7th Update on Fabry Disease Delprete C, Uhlig F, Caprini M, Hyland NP (2022) Does lyso-Gb3 play a causal role in gastrointestinal symptomology in Fabry disease? 7th Update on Fabry Disease [Details] | |
| (2022) | Gut Microbiome and Mucosa-Associated Infectious Disease: Mining for Antimicrobials and Postbiotics with Therapeutic Potential Focused Meeting Uhlig F, Warda A, Hueston C, Draper L, Chauvière G, Eckhardt E, Hill C, Hyland N (2022) Effects of a postbiotic consisting of heat-treated lactobacilli fermentate on mouse small intestinal ion transport and motility ex-vivo Gut Microbiome and Mucosa-Associated Infectious Disease: Mining for Antimicrobials and Postbiotics with Therapeutic Potential Focused Meeting [Details] | |
| (2022) | College of Medicine & Health Molecules to People Conference Uhlig F, Delprete C, Caprini M, Hyland N (2022) Does lyso-Gb3 play a causal role for gastrointestinal symptomology in Fabry disease? College of Medicine & Health Molecules to People Conference [Details] | |
| (2022) | BioMedEng22 Boys AJ, Güemes Gonzalez A, Uhlig F, Malliaras GG, Hyland NP, Owens RM (2022) Bioelectronic Devices for In Vivo Recordings of the Enteric Nervous System BioMedEng22 [Details] | |
| (2022) | Europhysiology 2022 Uhlig, F. and Warda, A. and Hueston, C. M. and Draper, L. and Chauviere, G. and Eckhardt, E. and Hill, C. and Hyland, N. (2022) Effects of a postbiotic consisting of heat-treated lactobacilli fermentate on mouse small intestinal ion transport and motility ex vivo Europhysiology 2022 , pp.657-659 [Details] | |
| (2020) | Federation of Neurogastroenterology and Motility Meeting Walsh, Jacinta and Cussotto, Sofia and Strain, Conall R. and Fouhy, Fiona and Stanton, Catherine and Dinan, Timothy G. and Hyland, Niall P. and Clarke, Gerard and Cryan, John F. and Griffin, Brendan T. (2020) Differential effects of the gut microbiota on the pharmacokinetics of antipsychotic drugs Federation of Neurogastroenterology and Motility Meeting [Details] | |
| (2019) | BNA2019 Festival of Neuroscience, Dublin, Ireland O’Donovan SM, Crowley E, O’Leary OF, Timmons S, Nolan YM, O’Sullivan O, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2019) The brain ↔ gut axis in Parkinson’s disease: enteric nervous system pathology and gut microbiome alterations in the AAV-synuclein rat model BNA2019 Festival of Neuroscience, Dublin, Ireland [Details] | |
| (2019) | NeuroGASTRO 2019 Walsh, J. and Boehme, M. and Cryan, John. F. and Dinan, Timothy. G. and Griffin, Brendan. T. and Clarke, G. and Hyland, Niall. P. (2019) The impact of a prebiotic mix, FOS-inulin, on hepatic drug-metabolising enzymes and drug efflux transporter NeuroGASTRO 2019 [Details] | |
| (2018) | Vitafoods 2018 V.D. Felice, D.M. O’Gorman, N.M. O’Brien, N.P. Hyland (2018) Bioaccessibility and bioavailability of Aquamin-Mg Vitafoods 2018 [Details] | |
| (2018) | Irish Society of Gastroenterology Walsh J, Van de Wouw M, Moloney GM, Cryan JF, Dinan TG, Griffin BT, Hyland NP and Clarke G (2018) The Impact of the Gut Microbiota on Hepatic Drug-Metabolising Enzymes: Potential Implications for Clinical Practice of Neurogastroenterology Irish Society of Gastroenterology [Details] | |
| (2018) | Federation of Neurogastroenterology and Motility Meeting Walsh, J. and van de Wouw, M. and Moloney, G. and Cryan, J. and Dinan, T. and Griffin, B. and Hyland, N. and Clarke, G. (2018) The impact of the gut microbiota on hepatic drug-metabolising enzymes: Potential implications for clinical practise of neurogastroenterology Federation of Neurogastroenterology and Motility Meeting [Details] | |
| (2018) | Young Neuroscience Ireland Symposium 2018, 25th October, University College Dublin, Ireland O’Donovan SM, Dolan E, O’Leary OF, Timmons S, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2018) The Brain ↔ Gut Axis in Parkinson’s disease (PD): Alterations in Enteric Nervous System Pathology and Gut Microbiome in the rAAV-α-synuclein Rat Model of PD Young Neuroscience Ireland Symposium 2018, 25th October, University College Dublin, Ireland [Details] | |
| (2017) | International Conference on Food Digestion V.D. Felice, D.M. O’Gorman, N.M. O’Brien, N.P. Hyland (2017) Evaluation of the Intestinal Transport and Bioavailability of calcium from a Multimineral Natural Product, Aquamin International Conference on Food Digestion [Details] | |
| (2017) | Irish Association of Pharmacologists Walsh J, Griffin BT, Hyland NP, Clarke GC (2017) Host and Environmental Factors Influencing Expression of Bacterial-derived Metabolic Enzymes in Faeces: Potential implications for Microbiota-mediated Drug Metabolism Irish Association of Pharmacologists [Details] | |
| (2017) | NeuroGASTRO 2017 O'Donovan, S. and Crowley, E. K. and Browne, J. and O'Sullivan, O. and O'Leary, O. F. and Timmons, S. and Nolan, Y. M. and O'Toole, P. W. and Clarke, D. J. and Hyland, N. P. and Joyce, S. A. and Sullivan, A. M. and O'Neill, C. (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome NeuroGASTRO 2017 , pp.33-34 [Details] | |
| (2017) | NeuroGASTRO 2017 Golubeva, A. and Joyce, S. and Moloney, G. and Burokas, A. and Sherwin, A. and Arboleya, S. and Murphy, K. and Hyland, N. and Stanton, C. and Clarke, G. and Gahan, C. and Dinan, T. and Cryan, J. (2017) Microbiota-related changes in bile acid and serotonin metabolism are associated with gastrointestinal dysfunction in a mouse model of autism NeuroGASTRO 2017 , pp.59-60 [Details] | |
| (2017) | NeuroGASTRO 2017 Golubeva, A. and Kandil, D. and Arboleya, S. and Burokas, A. and Murphy, K. and Stanton, C. and Hyland, N. and Clarke, G. and Dinan, T. and Schellekens, H. and Cryan, J. (2017) Obesity-induced alterations in colonic transit are normalized by dietary prebiotic supplementation: Role of gut microbiota NeuroGASTRO 2017 , pp.25-26 [Details] | |
| (2017) | NeuroGASTRO 2017 Bassett, S. and Young, W. and Fraser, K. and Webster, J. and Dalziel, J. and Ryan, L. and Cryan, J. and Dinan, T. and Stanton, C. and Clarke, G. and Hyland, N. and Roy, N. (2017) Stress differentially alters the plasma and brain metabolomes and caecal microbiome in Wistar Kyoto and Sprague Dawley rats NeuroGASTRO 2017 [Details] | |
| (2017) | The 7th International Human Microbiome Congress (IHMC), June 26-28th, Killarney, County Kerry, Ireland O’Donovan SM, Crowley EK, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan Y, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) Gut microbiome alterations and enteric nervous system pathology in the alpha-synuclein rat model of Parkinson's disease The 7th International Human Microbiome Congress (IHMC), June 26-28th, Killarney, County Kerry, Ireland [Details] | |
| (2017) | AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders O’Donovan SM, Crowley E, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan YM, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) The brain ↔gut axis in Parkinson’s disease: defining gut pathology and the impact of exercise in the rAAV-α-synuclein rat model of PD AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders , 29-MAR-17 - 02-APR-17 [Details] | |
| (2016) | 14th International Congress of Toxicology in conjunction with the 10th Mexican Congress of Toxicology Hyland, N. P. (2016) Gut microbiome and host physiology 14th International Congress of Toxicology in conjunction with the 10th Mexican Congress of Toxicology [DOI] [Details] | |
| (2016) | Experimental Biology Meeting Golubeva, Anna V. and Martin, R. M. and Kandil, D. and Schellekens, H. and Hyland, N. P. and Dinan, T. G. and Cryan, J. F. (2016) Dietary Prebiotic Supplementation Normalizes Delayed Colonic Transit in Obese Mice Experimental Biology Meeting San Diego, USA, [Details] | |
| (2015) | Proceedings of the British Pharmacological Society Rizzo E., Golubeva AV., Cryan JF., O'Reilly BA., Hyland NP (2015) Microbiota Regulation of Bladder Toll-like Receptor Expression in Male and Female Mice Proceedings of the British Pharmacological Society [Details] | |
| (2014) | Junior Scientists ECNP Workshop on Neuropsychopharmacology 2014, Nice, France Golubeva AV, Crampton SJ, Desbonnet L, Edge D, Lomasney KW, Hyland NP, O'Halloran KD, Dinan TG, O'Keeffe GW, Cryan JF (2014) P.4.011 Differential negative impact of prenatal stress on physiological systems in adulthood Junior Scientists ECNP Workshop on Neuropsychopharmacology 2014, Nice, France [DOI] [Details] | |
| (2014) | Society for Neuroscience (SFN) Neuroscience 2014, November 15-19, Washington, USA Borre YE, Hecke Morais L, Golubeva AV, Patterson E, Crispie F, Moloney RD, Scott KA, Stilling R, Hyland NP, Clarke G, Stanton C, Cotter PD, Dinan TG, Cryan JF. (2014) Mode of delivery at birth and behavioural outcomes: Rewiring of the brain-gut-microbiome axis? Society for Neuroscience (SFN) Neuroscience 2014, November 15-19, Washington, USA , 15-NOV-14 - 19-NOV-14 [Details] | |
| (2014) | Digestive Disease Week Kevin W. Lomasney , John F. Cryan , Niall P. Hyland (2014) Probiotics Influence Colonic Secretomotor Function and Gastrointestinal Physiology in the Mouse: In Vitro and In Vivo Studies With Bifidobacterium Infantis 35624 and Lactobacillus Salivarius UCC118 Digestive Disease Week , pp.S-135-S-136 [DOI] [Details] | |
| (2013) | Digestive Disease Week Sinead Heuston , Eamonn M. Quigley , Niall P. Hyland (2013) Assessment of Chymase Inhibition on Acute restraint Stress-Induced Visceral Hypersensitivity and Intestinal Dysfunction In Vivo Digestive Disease Week [DOI] [Details] | |
| (2013) | ECNP Workshop Golubeva AV, Crampton S, Desbonnet L, Edge D, Lomasney KW, Hyland NP, O'Halloran KD, Dinan TG, O'Keeffe GW, Cryan JF (2013) Differential negative impact of prenatal stress on physiological systems in adulthood ECNP Workshop [Details] | |
| (2013) | Pharmacology 2013 Florian Kratz, Sinead Heuston, Lis London, Paul Ross, Catherine Stanton, Aileen Houston, Niall Hyland (2013) Bacterial-derived gamma-aminobutyric acid significantly attenuates proliferation of human colon adenocarcinoma cells in vitro Pharmacology 2013 Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol11Issue3abst043P.pdf, [Details] | |
| (2012) | Digestive Disease Week Kevin W. Lomasney , John F. Cryan , Niall P. Hyland (2012) γ-Amino-Butyric Acid Regulates Submucosal Cholinergic Signalling and Secretomotor Function in Mouse Colon Digestive Disease Week [DOI] [Details] | |
| (2012) | British Pharmacological Society Winter Meeting 2012 NP Hyland, T Inkinen, S Grenham, EK Brint (2012) Toll Like Receptor Ligands Differentially Regulate Expression Of Colonic Epithelial Muscarinic Receptors In a Ligand-Specific and Temporal Manner British Pharmacological Society Winter Meeting 2012 Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol10Issue4abst036P.pdf, [Details] | |
| (2012) | Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy N. HYLAND, S. CARROLL, S. HEUSTON, E. QUIGLEY and J. CRYAN (2012) An investigation of the therapeutic potential of chymase- containing mast cells in a preclinical model of irritable bowel syndrome and their translational relevance Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy [Details] | |
| (2012) | Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy B. LOBO, M. TRAMULLAS, B.-C. FINGER, K. W. LOMASNEY, J. SANTOS, N. P. HYLAND, T. DINAN and J. F. CRYAN (2012) Psychosocial chronic stress induces intestinal dysmotility and changes in enteric nervous system in proximal colon Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy [Details] | |
| (2012) | Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy K. LOMASNEY, J. CRYAN and N. HYLAND (2012) Gamma-aminobutyric acid regulates submucosal cholinergic signalling and secretomotor function in mouse colon Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy [Details] | |
| (2012) | Digestive Disease Week Sinead Heuston, Eamonn M. Quigley, Niall P. Hyland (2012) Chymase-Containing Mast Cells are Significantly Increased in Patients With Irritable Bowel Syndrome: A Role in Epithelial Permeability? Digestive Disease Week [Details] | |
| (2012) | Digestive Disease Week Ambrose M, Moloney G, Heuston S, Rahman A, Davies JM, Murphy C, Hurley G, Quinlan A, Karras J, Hessel EM, Prinjha R, Lee K, Hyland NP, Shanahan F, Hammarstrom M-L, Melgar S, Nally K (2012) MiR-375 is a Key Regulator of Intestinal Homeostasis in Response to Inflammatory Stress Digestive Disease Week [Details] | |
| (2012) | British Pharmacological Society Winter Meeting 2012 Fernandes P, Hyland NP, Houston A (2012) Sensitivity of Human and Murine Colonic Tumour Cell Lines to Gamma-aminobutyric Acid (GABA) In Vitro British Pharmacological Society Winter Meeting 2012 Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol10Issue4abst044P.pdf, [Details] | |
| (2011) | British Pharmacological Society Winter Meeting O’Connell S, O’Mahony SM and Hyland NP (2011) 5-HT2B receptors regulate enteric neurotransmission in the submucosal plexus of rat colon British Pharmacological Society Winter Meeting [Details] | |
| (2011) | Neuroscience Ireland • Felice VD, Bravo J, Hyland NP, Dinan TG, Cryan JF, O’Mahony SM (2011) Visceral hypersensitivity induced by early-life stress is reduced by a selective 5-HT2b receptor antagonist and is not associated in increased expression of this receptor in brain areas associated with the emotional aspects of pain Neuroscience Ireland [Details] | |
| (2011) | British Pharmacological Society Winter Meeting Lomasney KW, Cryan JF and Hyland NP (2011) Effects of the gut microbiota on colonic secretomotor function British Pharmacological Society Winter Meeting [Details] | |
| (2010) | Translational Health Research Conference, UCC, Cork O’Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP (2010) CRF1 receptor-dependent activation of submucosal neurones by colonic supernatants from maternally separated rats Translational Health Research Conference, UCC, Cork [Details] | |
| (2010) | European Neuropsychopharmacology Cryan, J,Bravo, JA,Clarke, G,Hyland, NP,O'Malley, D,O'Mahony, D,Julio-Pieper, M,McKernan, DP,Tramullas, M,Dinan, TG (2010) Animal models of co-morbid depression and irritable bowel syndrome European Neuropsychopharmacology , pp.179-180 [DOI] [Details] | |
| (2010) | Digestive Disease Week O'Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP (2010) CRF1 receptor-dependent activation of submucosal neurones by colonic supernatants from maternally separated rats Digestive Disease Week [Details] | |
| (2010) | Digestive Disease Week Pruteanu, M; Hyland, NP; Clarke, D; Kiely, B; Shanahan, F; (2010) Bacterial proteolytic profile in inflammatory bowel diseases Digestive Disease Week [Details] | |
| (2009) | Digestive Disease Week McKernan DP, Nolan A, O'Mahony SM, Hyland NP, Brint E, Dinan TG, Cryan JF.; (2009) Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models of Chronic Stress: Relevance to Irritable Bowel Syndrome Digestive Disease Week [Details] | |
| (2009) | Digestive Disease Week Hyland NP, Bongiovanni C, O'Mahony CM, Fitzgerald P, Dinan TG, Cryan JF; (2009) The Combined Effects of Neonatal Psychological Stress and An Anxious Phenotype On Visceral Hypersensitivity and Colonic Function in Rats Digestive Disease Week [Details] | |
| (2009) | Digestive Disease Week Julio-Pieper M, Hyland NP, Cryan JF, Dinan TG; (2009) Group-III Metabotropic Glutamate Receptors Are Expressed in Rodent Colon: A Role in Cholinergically Induced Electrolyte Secretion Digestive Disease Week [Details] | |
| (2008) | Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 Clarke G, Mahony SM, Hyland NP, Fitzgerald P, Cryan JF, Dinan TG (2008) Visceral pain and beta3 adrenoceptor modulation a role for the kynurenine pathway? Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 [Details] | |
| (2008) | Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 Hyland, NP, O’ Callaghan K, O’Malley, D, Lee, K, Dinan, TG, Cryan, JF (2008) Differential cholinergic sensitivity in the enteric nervous system in two models of visceral hypersensitivity Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 [Details] | |
| (2008) | European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders (Cork, Ireland, September 2008) Clarke, G,O'Mahony, S,Hyland, NP,Fitzgerald, P,Dinan, TG,Cryan, JF (2008) Beta3 adrenoceptor modulation of visceral pain - A possible role for the kynurenine pathway? European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders (Cork, Ireland, September 2008) , pp.671-672 [Details] | |
| (2008) | Digestive Disease Week Hyland NP, Gibney SM, Gosselin RD, Lee K, Dinan TG, Cryan JF (2008) Assessment of colonic secretory function and faecal output in viscerally hypersensitive Wistar Kyoto rats Digestive Disease Week [Details] | |
| (2008) | Digestive Disease Week Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG & Cryan JF; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress? Digestive Disease Week San Diego, USA, , 01-JAN-08 - 01-JAN-08 [Details] | |
| (2008) | Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 Hyland NP, O'Mahony SM, Bulmer DC, Julio-Pieper M, Bongiovanni C, Dinan TG, Cryan JF; (2008) Beta3-adrenoceptor mediated secretion and localisation in the submucosal plexus of descending colon from maternally separated animals Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 [Details] | |
| (2007) | Digestive Disease Week Hyland NP, Chambers AP, Pittman QJ, Sharkey KA (2007) Diet-induced obesity confers protection against TNBS-induced colitis in rats Digestive Disease Week [Details] | |
| (2007) | Digestive Disease Week Hyland NP, Rybicka J, Macnaughton WK , Pittman QJ , Sharkey KA. ; (2007) A genetic predisposition to develop diet-induced obesity correlates with altered glucose transport and secretomotor function in a rat model Digestive Disease Week [Details] | |
| (2006) | Digestive Disease Week Hyland NP, Spencer SJ, Pittman QJ and Sharkey KA (2006) Neonatal lipopolysaccharide increases the severity of TNBS-induced colitis in adult rats Digestive Disease Week [Details] | |
| (2003) | British Pharmacological Society Hyland NP, Tough IR, Cox HM. (2003) Capsaicin-induced changes in ion transport across colonic mucosae are unaffected by neuropeptide Y Y1 or Y2 antagonism or Y1, Y2 or Y4 receptor knockout British Pharmacological Society [Details] | |
| (2003) | Enteric Nervous System 2003 Cox HM, Tough IR, Hyland NP. ; (2003) Neuropeptide Y Y1 and Y2 receptors mediate inhibitory tone in murine and human colon mucosae Enteric Nervous System 2003 , pp.195-237 [Details] | |
| (2003) | British Pharmacological Society Hyland NP, Cox HM. ; (2003) Differential role of Y1 and Y2 receptors mediating neuropeptide Y`s contribution to veratridine-induced ion transport across mouse colon British Pharmacological Society [Details] | |
| (2002) | British Pharmacological Society Hyland NP, Herzog H, Cox HM. ; (2002) Decreased sensitivity to pancreatic polypeptide in colonic mucosa from Y2 receptor knockout mice British Pharmacological Society [Details] | |
| (2002) | British Journal of Pharmacology Hyland NP, Cox HM. ; (2002) Effects of veratridine upon electrogenic ion transport across NPY knockout and wildtype mouse descending colon British Journal of Pharmacology [Details] | |
| (2000) | Digestive Disease Week Hornby PJ, Hyland NP, Fuchs KM, et al. (2000) Co-innervation of both the lower esophageal sphincter and gastric fundus by vagal preganglionic neurons in ferrets Digestive Disease Week [Details] | |
| (2000) | Digestive Disease Week Abrahams TP, Hyland NP, Hornby PJ (2000) Presence of NO synthase in vagal motor neurons innervating the lower esophageal sphincter in ferrets Digestive Disease Week [Details] | |
| (1999) | Society for Neuroscience AbrahamsTP, J Ekstrand, NP Hyland and PJ Hornby. ; (1999) Immunocytochemical localization of GABAB receptor in ferrets dorsal vagal complex and functional role in control of lower esophageal sphincter pressure Society for Neuroscience [Details] | |
| (1999) | Digestive Disease Week Hyland NP, R.H.Quinn, T.P. Abrahams and P.J.Hornby (1999) Vagal motor neurons innervating the lower esophageal sphincter in ferrets Digestive Disease Week [Details] |
Professional Activities
Conference Contributions
| Year | Publication | |
|---|---|---|
| (2024) | Invited Speaker, Federation of Neurogastroenterology and Motility Meeting, Niall Hyland (2024) Invited Speaker, ‘Impact of the microbiome on gut physiology’. [Invited Lectures (Conference)], Invited Speaker, Federation of Neurogastroenterology and Motility Meeting, Bangkok, Thailand . [Details] | |
| (2024) | Invited Faculty, Postgraduate Course “Navigating Solutions for DGBI and GI Motility Disorders”, Federation of Neurogastroenterology and Motility Meeting, Niall Hyland (2024) Invited Faculty, ‘Gut microbiota manipulation in DGBI’. [Invited Lectures (Conference)], Invited Faculty, Postgraduate Course “Navigating Solutions for DGBI and GI Motility Disorders”, Federation of Neurogastroenterology and Motility Meeting, Bangkok, Thailand . [Details] | |
| (2024) | Global Grant for Gut Health Colloquium - SpringerNature, Niall Hyland (2024) Invited Participant, 'Perspectives on challenges and solutions for the effective translation of microbiome-based therapies'. [Invited Lectures (Workshops)], Global Grant for Gut Health Colloquium - SpringerNature, Online . [Details] | |
| (2024) | Invited Speaker, 12th European Microbiome R&D and Business Collaboration Forum and Probiotics Congress, Niall Hyland (2024) Invited Speaker, ‘The stressed gut’. [Invited Lectures (Conference)], Invited Speaker, 12th European Microbiome R&D and Business Collaboration Forum and Probiotics Congress, The Hague, The Netherlands . [Details] | |
| (2024) | Invited Speaker, Future of the Microbiome Winter Summit, Niall Hyland (2024) Invited Speaker, 'The Stressed Gut and the Microbiome'. [Invited Lectures (Conference)], Invited Speaker, Future of the Microbiome Winter Summit, Online . [Details] | |
| (2023) | Invited Participant, GGGH 2023 Colloquium Annual Meeting, SpringerNature, Niall Hyland, (2023) Invited Participant, Global Grant for Gut Health Colloquium Annual Meeting. [Invited Lectures (Conference)], Invited Participant, GGGH 2023 Colloquium Annual Meeting, SpringerNature, Online . [Details] | |
| (2023) | Chair, NeuroGASTRO 2023 Biennial Meeting of the European Society of Neurogastroenterology and Motility, Niall Hyland (2023) Chair, Symposium 3 – Systemic Disease and GI Motility. [Invited Lectures (Conference)], Chair, NeuroGASTRO 2023 Biennial Meeting of the European Society of Neurogastroenterology and Motility, Bucharest, Romania . [Details] | |
| (2023) | Invited Plenary, NeuroGASTRO 2023 Biennial Meeting of the European Society of Neurogastroenterology and Motility, Niall Hyland (2023) Plenary Lecture, ‘The stressed gut and the microbiome’. [Invited Lectures (Conference)], Invited Plenary, NeuroGASTRO 2023 Biennial Meeting of the European Society of Neurogastroenterology and Motility, Bucharest, Romania . [Details] | |
| (2023) | Invited Speaker, Leibniz Institute for Natural Product Research and Infection Biology, Niall Hyland (2023) Invited Speaker, ‘Gut reactions: the xenobiotic-microbiome interface’. [Invited Lectures (Conference)], Invited Speaker, Leibniz Institute for Natural Product Research and Infection Biology, Leibniz, Germany . [Details] | |
| (2022) | Invited Speaker, British Association of Psychopharmacology, Niall Hyland (2022) Invited Speaker, ‘Psychotropic drugs and the microbiome’. [Invited Lectures (Conference)], Invited Speaker, British Association of Psychopharmacology, London, UK . [Details] | |
| (2022) | Invited Speaker, Microbiome Connect EU 2022, Niall Hyland (2022) Invited Speaker, ‘Microbiome-Enteric Nerve Interactions’. [Invited Lectures (Conference)], Invited Speaker, Microbiome Connect EU 2022, Amsterdam, The Netherlands . [Details] | |
| (2022) | Invited Speaker, Discovery Toxicology 2022: Science-led Strategies for Success in Discovery and Development Toxicology, British Toxicological Society, Niall Hyland (2022) Invited Speaker, ‘Gut Reactions: the xenobiotic-microbiota interface’. [Invited Lectures (Conference)], Invited Speaker, Discovery Toxicology 2022: Science-led Strategies for Success in Discovery and Development Toxicology, British Toxicological Society, Cheshire, UK, . [Details] | |
| (2022) | Invited Speaker, 1st Biomedicine and Health PhD Students Congress - Science and Us, University of Rijeka, Niall Hyland (2022) Invited Speaker, ‘Drug-Gut Microbiota Interactions’. [Invited Lectures (Conference)], Invited Speaker, 1st Biomedicine and Health PhD Students Congress - Science and Us, University of Rijeka, Rijeka, Croatia . [Details] | |
| (2021) | Speaker, International Academy of Toxicological Pathology (IATP) Satellite Symposium (online), Biomarkers for the 21st Century: The Critical Role of the Microbiome in Toxicology, Health and Disease, Niall Hyland (2021) Invited Speaker, ‘The microbiota-gut-brain axis’. [Invited Lectures (Conference)], Speaker, International Academy of Toxicological Pathology (IATP) Satellite Symposium (online), Biomarkers for the 21st Century: The Critical Role of the Microbiome in Toxicology, Health and Disease, Online . [Details] | |
| (2021) | Chair, NeuroGASTRO 2021 - Biennial Meeting of the European Society of Neurogastroenterology and Motility, Niall Hyland (2021) Chair, Symposium 11 – Microbiome. [Chair Sessions at Symposia], Chair, NeuroGASTRO 2021 - Biennial Meeting of the European Society of Neurogastroenterology and Motility, Online . [Details] | |
| (2021) | Invited Speaker, Microbiome Connect: Gut Therapeutics Europe, Niall Hyland (2021) Invited Speaker, ‘Latest Research Into How Drugs and the Microbiome Interact’. [Invited Lectures (Conference)], Invited Speaker, Microbiome Connect: Gut Therapeutics Europe, Amsterdam, The Netherlands . [Details] | |
| (2020) | Symposium Organiser and Chair, Pharmacology 2020, Niall Hyland (2020) Symposium Organiser and Chair, 'Drug-Gut Microbiota Interactions'. [Chair Sessions at Symposia], Symposium Organiser and Chair, Pharmacology 2020, Online . [Details] | |
| (2020) | Invited Speaker, Fresh research on the gut microbiome, Nature Research webcasts, Niall Hyland (2020) Invited Speaker, ‘Drug-Gut Microbiota Interactions’. [Invited Lectures (Workshops)], Invited Speaker, Fresh research on the gut microbiome, Nature Research webcasts, Online . [Details] | |
| (2020) | Invited Speaker, PhD Program in Pharmacological Sciences, Enteric Neurosciences Workshop, Niall Hyland (2020) Invited Speaker, ‘Drug-Gut Microbiota Interactions’. [Invited Lectures (Conference)], Invited Speaker, PhD Program in Pharmacological Sciences, Enteric Neurosciences Workshop, Padova, Italy . [Details] | |
| (2019) | Invited Speaker, Knowledge for Growth, Niall Hyland (2019) Invited Speaker, ‘Microbiota and the gut brain axis’ in the Personalised Medicine symposium. [Invited Lectures (Conference)], Invited Speaker, Knowledge for Growth, Ghent, Belgium . [Details] | |
| (2019) | Invited Speaker, 2nd Symposium of Probiotics in Digestive Medicine, Niall Hyland (2019) Invited Speaker, ‘The Microbiome and GI Physiology’. [Invited Lectures (Conference)], Invited Speaker, 2nd Symposium of Probiotics in Digestive Medicine, Pula, Croatia . [Details] | |
| (2018) | Invited Speaker, Coloplast Ostomy Days, Niall Hyland (2018) Invited Speaker, ‘Gut-brain axis and how intestinal flora interacts with the brain’. [Invited Lectures (Conference)], Invited Speaker, Coloplast Ostomy Days, Copenhagen, Denmark . [Details] | |
| (2017) | Invited Speaker, 14th European International Society for the Study of Xenobiotics (ISSX) Meeting, Niall Hyland (2017) Invited Speaker, ‘Regulation of Host Gastrointestinal Physiology with a Focus on the Interactions Between the Microbiome, Gut, and the Brain’ in symposium entitled Understanding and Targeting the Human Microbiome. [Invited Lectures (Conference)], Invited Speaker, 14th European International Society for the Study of Xenobiotics (ISSX) Meeting, Cologne, Germany . [Details] | |
| (2017) | Invited Speaker, 4th European Microbiome R&D and Business Collaboration Forum and Probiotics Congress, Niall Hyland (2017) Invited Speaker, ‘Mast Cells, Microbes and the Gut-brain Axis’. [Invited Lectures (Conference)], Invited Speaker, 4th European Microbiome R&D and Business Collaboration Forum and Probiotics Congress, Amsterdam, The Netherlands . [Details] | |
| (2016) | Symposium Organiser and Speaker, Pharmacology 2016, Niall Hyland (2016) Symposium Organiser and Speaker, ‘Bacterial signalling in the gut-brain axis’ in symposium entitled The long reach of the bowel: Translating microbiome science into therapeutics for systemic human diseases. [Invited Lectures (Conference)], Symposium Organiser and Speaker, Pharmacology 2016, London, United Kingdom . [Details] | |
| (2016) | Invited Speaker, XIV International Congress of Toxicology, Niall Hyland (2016) Invited Speaker, ‘Gut microbiome and host physiology’. [Invited Lectures (Conference)], Invited Speaker, XIV International Congress of Toxicology, Merida, Mexico . [Details] | |
| (2016) | Invited Speaker, Society on NeuroImmune Pharmacology: SNIP, Krakow, Poland, April 4th - 6th, 2016, NIall Hyland (2016) Invited speaker; Mast cells, microbes and the gut-brain axis in symposium entitled Neuroinflammation and the Gut: What is its relevance to HIV infection, neurological pathology, and therapy? Neurodegenerative Responses to Viral Infections and Therapeutics. [Invited Oral Presentation], Invited Speaker, Society on NeuroImmune Pharmacology: SNIP, Krakow, Poland, April 4th - 6th, 2016, Krakow, Poland , 06-APR-16 - 09-APR-16. [Details] | |
| (2016) | Invited Speaker, Neuroimmunophysiology of the Gastrointestinal Tract 2016: new paradigms to understand inflammatory and motility disorders of the gut, Niall Hyland (2016) Invited Speaker, ‘Micobes, mast cells and enteric physiology’. [Invited Lectures (Conference)], Invited Speaker, Neuroimmunophysiology of the Gastrointestinal Tract 2016: new paradigms to understand inflammatory and motility disorders of the gut, Banff, Canada, . [Details] | |
| (2016) | Chair and Discussion Panelist, Probiota 2016, NIall Hyland (2016) Chairperson - Panel discussion Opportunities for life?. [Chair Sessions at Symposia], Chair and Discussion Panelist, Probiota 2016, Amsterdam, The Netherlands . [Details] | |
| (2016) | Invited Speaker, 49th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition in Athens, 25–28 May 2016, NIall Hyland (2016) Invited speaker; Influence of the microbiome on host gut function and physiology in Basic Science Symposium: From bench to bedside in paediatric gastroenterology. [Oral Presentation], Invited Speaker, 49th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition in Athens, 25–28 May 2016, Athens, Greece , 25-MAY-16 - 28-JUL-16. [Details] | |
| (2015) | Chair and Poster Referee, Pharmacology 2015, NIall Hyland (2015) Annual Meeting of the British Pharmacological Society - Chair Oral Sessions; Referee Poster Presentations. [Conference Organising Committee Member], Chair and Poster Referee, Pharmacology 2015, London . [Details] | |
| (2014) | Invited Speaker, Probiota 2014, Niall P Hyland (2014) Invited Speaker, 'The gut-brain axis: The potential mood-boosting effects of pre-probiotics'. [Invited Oral Presentation], Invited Speaker, Probiota 2014, Netherlands . [Details] | |
| (2014) | Plenary Speaker, 2nd World Congress on Targeting Microbiota, Niall P Hyland (2014) Plenary Speaker, 'Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour'. [Plenary Lecture], Plenary Speaker, 2nd World Congress on Targeting Microbiota, France . [Details] | |
| (2014) | Lecture Presentation, Digestive Disease Week 2014, Niall P Hyland (2014) Lecture presentation as part of the Neurogastroenterology & Motility Distinguished Abstract Plenary at Digestive Disease Week held in Chicago. [Plenary Lecture], Lecture Presentation, Digestive Disease Week 2014, USA . [Details] | |
| (2013) | Poster Referee, Pharmacology 2013, Niall P Hyland (2013) Referee for poster prizes; Pharmacology 2013 (formerly the BPS Winter Meeting) attracts around 800 scientists each year, mostly from the UK but also many from across Europe and from overseas. The meeting includes a selection of topical symposia, plenary lectures, free oral communications and poster sessions which cover the many aspects of pharmacology from basic to clinical science. [Referee], Poster Referee, Pharmacology 2013, United Kingdom . [Details] | |
| (2012) | Abstract Review Committee, Digestive Disease Week 2012, Niall P Hyland (2012) American Gastroenterological Association, Abstract Review Committee; Physiology of the GI Tract: Motility, Secretion, Sensation section. [Referee], Abstract Review Committee, Digestive Disease Week 2012, USA . [Details] | |
| (2012) | Abstract Review Committee, Digestive Disease Week 2012, Niall P Hyland (2012) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Abstract Review Committee, Digestive Disease Week 2012, USA . [Details] | |
| (2012) | Symposium Chair, Digestive Disease Week 2012, Niall P Hyland (2012) Symposium Co-chair, Physiology of the GI Tract: Motility Secretion Sensation Research Forum. [Chair Sessions at Symposia], Symposium Chair, Digestive Disease Week 2012, USA . [Details] | |
| (2012) | Selected Participant and Speaker, XIIth Little Brain Big Brain Meeting, Niall P Hyland (2012) Speaker; An investigation of the therapeutic potential of chymase-containing mast cells in a preclincal model of irritable bowel syndrome and their translational relevance. [Oral Presentation], Selected Participant and Speaker, XIIth Little Brain Big Brain Meeting, Belgium . [Details] | |
| (2012) | Selected Speaker, Joint International Neurogastroenterology and Motility Meeting,, Niall P Hyland (2012) Best of Little Brain Big Brain - Selected Speaker. [Invited Oral Presentation], Selected Speaker, Joint International Neurogastroenterology and Motility Meeting,, Italy . [Details] | |
| (2011) | Selected Participant and Speaker, Johnson & Johnson Corporate Office of Science And Technology Microbiome Symposium, Niall P Hyland (2011) Invited Speaker, 'The microbiome-gut-brain axis: From bowel to behaviour'. [Invited Oral Presentation], Selected Participant and Speaker, Johnson & Johnson Corporate Office of Science And Technology Microbiome Symposium, USA . [Details] | |
| (2011) | Abstract Review Committee, Digestive Disease Week 2011, Niall P Hyland (2011) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Abstract Review Committee, Digestive Disease Week 2011, USA . [Details] | |
| (2010) | Abstract Review Committee, Digestive Disease Week 2010, Niall P Hyland (2010) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Abstract Review Committee, Digestive Disease Week 2010, USA . [Details] | |
| (2010) | Symposium Chair, Digestive Disease Week 2010, Niall P Hyland (2010) Symposium Co-chair, Enteric Nervous System and Enteroendocrine Signaling in the Gut Research Forum. [Chair Sessions at Symposia], Symposium Chair, Digestive Disease Week 2010, USA . [Details] | |
| (2009) | Abstract Review Committee, Digestive Disease Week 2009, Niall P Hyland (2009) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Abstract Review Committee, Digestive Disease Week 2009, USA . [Details] | |
| (2009) | Selected Participant and Speaker, Little brain-Big brain XI, a satellite symposium of the International Society of Neurogastroenterology and Motility Meeting, Niall P Hyland (2009) Selected Participant and Speaker, 'The combined effects of neonatal psychological stress and an anxious phenotype on visceral hypersensitivity and colonic function in rats'. [Oral Presentation], Selected Participant and Speaker, Little brain-Big brain XI, a satellite symposium of the International Society of Neurogastroenterology and Motility Meeting, USA . [Details] | |
| (2009) | Selected Speaker, International Society of Neurogastroenterology and Motility Meeting, Chicago, September 2009, Niall P Hyland (2009) Speaker; 'The combined effects of neonatal psychological stress and an anxious phenotype on visceral hypersensitivity and colonic function in rats'. [Oral Presentation], Selected Speaker, International Society of Neurogastroenterology and Motility Meeting, Chicago, September 2009, USA . [Details] | |
| (2009) | Symposium Chair, Digestive Disease Week 2009, Niall P Hyland (2009) Symposium Co-chair, Brain-Gut Interactions and Neuroimaging Research Forum. [Chair Sessions at Symposia], Symposium Chair, Digestive Disease Week 2009, USA . [Details] | |
| (2008) | Abstract Review Committee, Digestive Disease Week 2008, Niall P Hyland (2008) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Abstract Review Committee, Digestive Disease Week 2008, USA . [Details] | |
| (2007) | Irish Society of Gastroenterology, Winter Meeting, Hyland NP, Dinan TG, Cryan JF; (2007) Stress susceptible Wistar Kyoto rats display altered epithelial cholinergic sensitivity in the distal colon. [Poster Presentation], Irish Society of Gastroenterology, Winter Meeting, Dublin, Ireland , 01-DEC-07 - 01-DEC-07. [Details] | |
| (2006) | Speaker, Canadian Association of Gastroenterology, Research Topics in GI Disease VI, Niall P Hyland (2006) Speaker, 'Small intestinal secretory and absorptive function is significantly altered in outbred diet-induced obese compared to diet resistant rats'. [Oral Presentation], Speaker, Canadian Association of Gastroenterology, Research Topics in GI Disease VI, Ontario, Canada , 01-OCT-06 - 31-OCT-06. [Details] | |
| (2006) | Speaker, Shaffer Awards, University of Calgary, Niall P Hyland (2006) Speaker, 'Neonatal immune challenge exacerbates colonic damage and elevates plasma TNFa during TNBS-colitis in adult rats'. [Oral Presentation], Speaker, Shaffer Awards, University of Calgary, University of Calgary, Canada , 01-APR-06 - 30-APR-06. [Details] | |
| (2005) | Speaker, Gastrointestinal Research Group and Immunology Research Group first joint research symposium, University of Calgary, Niall P Hyland (2005) Speaker, 'Neonatal lipopolysaccharide increases the severity of TNBS-induced colitis in adult rats'. [Oral Presentation], Speaker, Gastrointestinal Research Group and Immunology Research Group first joint research symposium, University of Calgary, Kananaskis, Alberta, Canada , 01-OCT-05 - 31-OCT-05. [Details] |
Honours and Awards
| Year | Title | Awarding Body | |
|---|---|---|---|
| 2022 | Honorary Fellowship, British Pharmacological Society | British Pharmacological Society | |
| 2022 | Editors’ Performance Award, British Journal of Pharmacology | British Journal of Pharmacology | |
| 2022 | Nominee, UCC President's Award for Excellence in Teaching | University College Cork | |
| 2021 | Fellowship, British Pharmacological Society | British Pharmacological Society | |
| 2020 | APC Microbiome Ireland Education and Public Engagement Champion | APC Microbiome Ireland | |
| 2018 | Failte Ireland Conference Ambassador Award | Failte Ireland | |
| 2008 | Poster of distinction (American Gastroenterological Association) | Neurogastroenterology & Motility Joint International Meeting, Lucerne, Switzerland | |
| 2004 | Research Initiative Award, Canadian Association of Gastroenterology | Canadian Association of Gastroenterology | |
| 2007 | Poster of distinction (American Gastroenterological Association) | American Gastroenterological Association, | |
| 2006 | Student Choice Award for best oral presentation (Shaffer Research Award) | Gastrointestinal Research Group, University of Calgary, Shaffer Awards | |
| 2003 | Travel Bursary (Merck Eurolab) | Merck Eurolab | |
| 2002 | Oral communication prize (King's College London, School of Biomedical Sciences) | Guy's King's and St. Thomas' School of Biomedical Sciences | |
| 2001 | Poster prize (6th International Neuropeptide Y Conference) | 6th International Neuropeptide Y Conference | |
| 2001 | Travel Bursary (Merck Eurolab) | Merck Eurolab | |
| 1999 | Travel Award (Louisiana State University Medical Center, Center for Neuroscience Excellence) | Louisiana State University Medical Center, Center for Neuroscience Excellence | |
| 2009 | Poster of Distinction (American Gastroenterological Association) | American Gastroenterological Association |
Journal Activities
| Journal | Role | To / From | |
|---|---|---|---|
| Pharmacology Research & Perspectives | Editor | - | |
| British Journal Of Pharmacology | Editor | - | |
| British Journal Of Pharmacology | Guest Editor | - | |
| Frontiers In Neuroscience | Member of Editorial Board | - | |
| Frontiers In Physiology | Member of Editorial Board | - | |
| Frontiers In Endocrinology | Member of Editorial Board | - | |
| Translational Psychiatry | Referee | - | |
| Brain Behav Immun | Referee | - | |
| Nature Communications | Referee | - | |
| European Journal Of Pain | Referee | - | |
| European Neuropsychopharmacology | Referee | - | |
| British Journal Of Pharmacology | Referee | - | |
| Neuropharmacology | Referee | - | |
| American Journal Of Physiology-Regulatory Integrative And Comparative Physiology | Referee | - | |
| Plos One | Referee | - | |
| Bmc Gastroenterology | Referee | - | |
| American Journal Of Physiology-Gastrointestinal And Liver Physiology | Referee | - | |
| The Journal Of Physiology | Referee | - | |
| Marine Drugs | Referee | - | |
| Nutritional Neuroscience | Referee | - | |
| Scandinavian Journal Of Gastroenterology | Referee | - | |
| Psychopharmacology | Referee | - | |
| Neurogastroenterol & Motility | Referee | - |
Professional Associations
| Association | Function | From / To | |
|---|---|---|---|
| European Society of Neurogastroenterology and Motility | Member | / | |
| British Pharmacological Society | Member | / |
Patents
| Patent Number | Title | Granted | |
|---|---|---|---|
| AU2024901496A0 | Strains, compositions and methods and uses thereof | 21-MAY-24 | |
| AU2024901497A0 | Strains, compositions and methods and uses thereof | 21-MAY-24 |
Consultancy
| Client | Description | |
|---|---|---|
| Zentiva Group, a.s. | ||
| Johnson & Johnson Consumer Inc. | ||
| Steigerwald part of Bayer group | ||
| Janssen Pharmaceutical Companies of Johnson and Johnson |
Committees
| Committee | Function | From / To | |
|---|---|---|---|
| Academic Council UCC (2024 - present) | Member | / | |
| Animal Welfare Body UCC (2019 - present) | Member | / | |
| Conference UCC Steering Committee (2016 - present) | Member | / | |
| UCC Animal Experimentation and Ethics Committee (2016 - 2021) | Member | / | |
| UCC Scholarships & Prizes Working Group (2018 - 2019) | Member | / | |
| College of Medicine and Health Sabbatical Research Leave Committee (2024 - present) | Member | / | |
| College of Science, Engineering, and Food Science Teaching Learning and Student Experience Committee (2020 - present) | Member | / | |
| School of Medicine Athena Swan Working Group Chair - Evaluating Culture, Inclusion and Belonging (2023 - present) | Chair | / | |
| School of Medicine Athena Swan Self-Assessment Team (2020 - present) | Member | / | |
| Dental School & Hospital Teaching & Curriculum Committee (2018 - present) | Member | / | |
| Deputy for Head of Department on the School of Medicine Executive/Heads of Department Committee (2019 - 2023) | Member | / | |
| School of Medicine Graduate Entry to Medicine Teaching and Oversight Committee (2008 - 2018) | Member | / | |
| Chair Department of Physiology Graduate Studies Committee (2018 - present) | Chair | / | |
| Co-chair Department of Pharmacology & Therapeutics Graduate Studies Committee (2008 - 2018) | Co-chair | / | |
| School of Pharmacy BPharm Programme Board (2008 - 2009) | Member | / | |
| Chair APC Microbiome Ireland Wellbeing Committee (2021 - 2022) | Chair | / | |
| APC Microbiome Ireland Wellbeing Committee (2019 - 2022) | Member | / | |
| World Microbiome Day Organising Committee (2019 - present) | Member | / | |
| European Society of Neurogastroenterology and Motility (ESNM) Steering Committee (2015 - 2020) | National Representative fore Ireland and Member | / | |
| Vice President – Meetings, British Pharmacological Society (2017 - 2020) | Vice President | / | |
| Council, British Pharmacological Society (2017 - 2020) | Non-Trustee Member | / | |
| British Pharmacological Society Equality, Diversity and Inclusion Project Steering Group (2018 - 2020) | Member | / | |
| British Pharmacological Society Open Access Publishing Working Group (2018 - 2020) | Member | / | |
| Finance Committee, British Pharmacological Society (2017 - 2019) | Member | / | |
| Systems and Integrative Pharmacology Affinity Group, British Pharmacological Society (2015 - 2017) | Co-Chair | / | |
| Meetings Committee, British Pharmacological Society (2012 - 2016) | Member | / | |
| American Gastroenterological Association (AGA) Institute Council (2014 - 2016) | Neurogastroenterology & Motility Section Councillor | / |
Outreach Activities
| Description | |
|---|---|
Mad Scientist Weekend, Robots, bugs and a virtual walk through the human digestive system were among the attractions on offer at the summer series of family-friendly educational weekends at Fota Wildlife Park, https://www.echolive.ie/corknews/arid-41433124.html and https://www.fotawildlife.ie/events/mad-scientist-weekend-2024/, July 13th 2024. | |
Budding Biologists Transition Year Programme, Budding Biologists TY Programme APC Microbiome Institute, https://www.ucc.ie/en/apc/outreach/, April 22nd-26th, 2024. | |
Physiology Week (The Physiological Society), Pedalling Passion: A Triumph in Physiology Week's Cyclathon & Blitz, https://www.ucc.ie/en/physiology/news/2023/pedaling-passion-a-triumph-in-physiology-weeks-cyclathon--blitz-.html, November 16th, 2023. | |
Cancer World Magazine, ‘Tackling drug resistance: how our commensal bacteria can hinder or help’ Cancer World Magazine ‘Tackling drug resistance: how our commensal bacteria can hinder or help’, https://cancerworld.net/tackling-drug-resistance-how-our-commensal-bacteria-can-hinder-or-help/, January 7th, 2022. | |
Microbiome Post, ‘Challenges to unlocking the real potential of gut brain axis’ Niall Hyland (APC Microbiome Ireland at University College Cork) discussed at Microbiome Connect congress 2022, https://microbiomepost.com/niall-hyland-challenges-to-unlocking-the-real-potential-of-gut-brain-axis/ & https://youtu.be/_chw4llISJA | |
Sligo Science Festival Week, ‘Mind Your Microbes: The Microbiota-Gut Brain Axis’ Sligo Science Festival Week (online), November 8th - November 13th, 2021, https://www.itsligo.ie/wp-content/uploads/2021/10/102862-Sligo-Science-Festival-Brochure-2.pdf | |
Cork Discovers, Research for Adults, 'Could your pills be making you ill?' Cork Discovers, Research for Adults, https://www.youtube.com/watch?v=lWmYZRXi91E, November 27th 2020 | |
Opinion Piece, October 12th 2019, J Prescr Prac ‘George Winter discusses the question whether microbes in the gut can affect the brain, and if it is possible to treat brain disorders by changing the composition of gut microbiota’, https://www.magonlinelibrary.com/doi/abs/10.12968/jprp.2019.1.10.482 | |
Irish Independent, ‘Could your pills be making you ill?’ Newspaper article, 11th December 2019, https://www.independent.ie/life/health-wellbeing/could-your-pills-be-making-you-ill | |
Sligo Champion newspaper, ‘Researching gut health’ Press Release, September 7th 2019, https://www.independent.ie/regionals/sligochampion/news/researching-gut-health-38451074.html | |
Spotify for podcasters, 'Dr Niall Hyland from UCC on the brain-gut connection' Radio Interview/ Podcast; An episode of Wellbeing for Everyday Life’, November 12th 2019 Dublin South FM, https://anchor.fm/maeve-halpin/episodes/Dr-Niall-Hyland-from-UCC-on-the-brain---gut-connection-e8v8mi & https://podcasters.spotify.com/pod/show/maeve-halpin/episodes/Dr-Niall-Hyland-from-UCC-on-the-brain---gut-connection-e8v8mi/a-a119uks | |
TechCentral.ie, 'UCC researcher wins international research grant for microbiome study' Press Release, August 30th 2019, TechCentral.ie, https://www.techcentral.ie/ucc-researcher-wins-international-research-grant-for-microbiome-study/ | |
Irish Examiner, ‘Irish Researcher Wins Global Grant’ Press Release, August 30th 2019, Irish Examiner, https://www.pressreader.com/ireland/irish-examiner/20190830/281681141547933 | |
'Understanding Life: Focus on Physiology', Clare Ray (Editor), Sarah Hall (Editor), Christopher Torrens (Editor), Angela Breslin, Yousef Alqurashi, Julia Attias, Daniel Brayson, Fan Chung, Niall Hyland, Thomas Smith, Christof Schwiening, Holly Shiels, Paul D. Taylor, Mike Tipton Aimed at undergraduates and 16-19 year-olds, this resource is an update of an earlier version and showcases some of the latest and most exciting areas of physiological research, reflecting the evolving nature of this discipline and why we study it. By continuing to develop our understanding of normal body processes, physiology can provide useful insights into how we can maintain our health on Earth and in extreme environments such as space. http://www.physoc.org/sites/default/files/mediaimages/Understanding%20Life%20Booklet_web.pdf | |
Thesis in 3, Jonathan Keane (PhD student), ‘The Modern Microbiome and Colon Cancer‘ Thesis in 3 showcases some of the innovative research currently happening in a number Science, Technology, Engineering and Maths research centres around the country. During the course of the event, the audience get to hear about the current world-class research happening in Ireland in bite-sized chunks, https://thesisin3.com/speakers-2016/. | |
UCC Science For All, Jonathan Keane (PhD student), 'The Modern Microbiome and Colon Cancer' Talking science without the jargon, https://www.ucc.ie/en/news/archive/2016/talking-science-without-the-jargon-.html | |
Evening Echo newspaper, 'Are your gut bacteria causing cancer? It could depend on your diet’ Jonathan Keane (PhD student; published 2016) | |
Thesis in 3, Kevin Lomasney (PhD student), ‘Probiotics - Miracle Bugs?' Thesis in 3 is an exciting national competition for research students from all over Ireland who have just 3 slides and 3 minutes to explain an entire thesis. The competition is designed to showcase the world-class research happening in Ireland in bite-sized chunks. https://youtu.be/A-ARN3Bz4S0?si=rAKfy04nLvisODfb |
Other Activities
| Description | |
|---|---|
Grant Reviewing Activity Recorder (like “rapporteur”) for The Health and Digital Executive Agency (HaDEA), HORIZON-HLTH-2024-DISEASE-09-01: European Partnership: One Health Anti-Microbial Resistance Remote evaluation Central evaluation - consensus meetings and panel meeting European Commission H2020 RIA - Genome, Environment, Microbiome & Metabolome in Autism: an integrated multi-omic systems biology approach to identify biomarkers for personalized treatment and primary prevention of Autism Spectrum disorder (GEMMA) Periodic Review Meeting with consortium FRA 2022 research funding program of Federico II University of Naples, Italy Deutsche Forschungsgemeinschaft (German Research Foundation) UK Research and Innovation - Future Leaders Fellowships BBSRC - Biotechnology and Biological Sciences Research Council UK – Responsive mode The Wellcome trust/DBT India Alliance Fellowship Research Foundation - Flanders (Fonds Wetenschappelijk Onderzoek - Vlaanderen, FWO – Postdoctoral Fellowships Joint transnational call of HDHL-INTIMIC - Interrelation of the Intestinal Microbiome, Diet and Health, cofunded by the European Union Stage 1 pre-proposal reviewer and rapporteur (Bonn, Germany) Stage 2 full proposal reviewer and rapporteur (Brussels, Belgium) Action for Ataxia telangiectasia (A-T; UK) European Research Council (ERC) - ERC Starting Grants Step 2 - Remote Referee Fonds National de la Recherche (FNR; Luxembourg) - CORE scheme Research Foundation - Flanders (Fonds Wetenschappelijk Onderzoek - Vlaanderen, FWO) French National Research Agency (ANR) - Generic Call Israel Science Foundation - Individual Research Grants Royal Netherlands Academy of Arts and Sciences (KNAW) - Programme of Strategic Scientific Alliances National Science Centre Poland - HARMONIA funding scheme NC3R (UK) World Cancer Research Fund International MRC - Medical Research Council UK - Research Boards | |
Conference Organisation Scientific Committee, Probiota Global, Copenhagen, Denmark (2025) Chair, AGA Institute’s abstract review process for Digestive Disease Week (2024) Scientific Committee, Probiota, Milan, Italy (2024) Scientific Committee, IPA World Congress + Probiota, Barcelona, Spain, (2023) Programme Committee, Translating Ideas into Therapies, Co-hosted BPS-ELRIG UK meeting, London, United Kingdom (2021) Scientific Programme Committee, NeuroGASTRO 2021, Virtual Meeting (2021) Executive Group, World Congress of Pharmacology 2022 (WCP2022), Glasgow, United Kingdom (2022) Scientific Committee, NeuroGASTRO 2019, Lisbon, Portugal (2019) Chair & Scientific Committee, Probiota 2018. Barcelona, Spain (2018) Local Organiser & Scientific Committee, NeuroGASTRO 2017, Cork, Ireland (2017) Chair & Scientific Committee, Probiota 2017. Berlin, Germany (2017) Scientific Committee, Probiota 2016. Amsterdam, The Netherlands (2016) Organising Committee, ASCEPT-BPS Joint Scientific Meeting – ‘Tomorrow’s medicines: pharmacology, patients and populations’. Hong Kong, China (2015) |
Employment
| Employer | Position | From / To | |
|---|---|---|---|
| Department of Physiology, University College Cork | Senior Lecturer in Physiology | 13-MAY-18 / | |
| Department of Pharmacology & Therapeutics, University College Cork | Lecturer in Pharmacology | 01-AUG-08 / 13-MAY-18 | |
| Alimentary Pharmabiotic Centre (University College Cork) | Senior Postdoctoral Fellow | 01-JAN-07 / 01-AUG-08 | |
| University of Calgary, Canada | Postdoctoral Fellow | 01-JAN-04 / 01-JAN-07 | |
| Louisiana State University Medical Center, USA | Visiting Research Fellow | 01-JUN-98 / 01-SEP-99 |
Education
| Year | Institution | Qualification | Subject | |
|---|---|---|---|---|
| 2024 | University College Cork | Continuing Professional Development Certificate in Digital Education | Digital Education | |
| 2020 | University College Cork/Irish Management Institute | Aspiring Leaders Senior Leadership Development | Aspiring Leaders Senior Leadership Development | |
| 2012 | University College Cork | Postgraduate Certificate in Teaching & Learning in Higher Education | Teaching & Learning in HE | |
| 2004 | King's College London | PhD Pharmacology | Pharmacology | |
| 2000 | University of Ulster, Coleraine, Northern Ireland. | BSc (Hons) Biomedical Sciences | Biomedical Sciences | |
| 2000 | University of Ulster, Coleraine, Northern Ireland. | Diploma in Industrial Studies | Industrial Studies |
Languages
| Language | Reading | Writing | Speaking | |
|---|---|---|---|---|
| English | Fluent | Fluent | Fluent |
Teaching Activities
Teaching Interests
Current Teaching CommitmentsAs Director of the BSc (Hons) Physiology and a Senior Lecturer at University College Cork (UCC), Dr Hyland leads interdisciplinary education across the College of Medicine and Health and the College of Science, Engineering, and Food Science (SEFS). His teaching responsibilities include module coordination, lecturing, and supervision across several undergraduate and postgraduate programmes, fostering collaborative learning environments and promoting innovative teaching methodologies.
Module Coordination and Lecturing
PL2034 – Physiology for Dental Students
Role: Coordinator and Lecturer
Credits: 10
Hours: 50
Dr Hyland coordinates and delivers lectures, tutorials, and assessments for this module, providing dental students with a solid foundation in physiology.
PL4015 – Microbiome & Physiology
Role: Coordinator and Lecturer
Credits: 5 Hours: 30
As the first microbiome-focused module at UCC, Dr Hyland designed and coordinates this course, which explores the role of the microbiome in physiology, using a combination of lectures, journal clubs, and student presentations.
PL3025 – Literature Review, Experimental Design, and Data Analysis
Role: Supervisor
Credits: 5
Hours: 20
Dr Hyland supervises students in this module, guiding them through literature reviews and the intricacies of experimental design and data analysis.
PL4020 – Research Project
Role: Coordinator and Supervisor
Credits: 20
Hours: 35
Dr Hyland leads this capstone module, supervising students as they undertake independent research projects, offering mentorship and evaluating their final research output.
MSc Nutrition & Behaviour (Bournemouth University)
Role: Guest Lecturer
Hours: 4
Dr. Hyland is a guest lecturer on this postgraduate course, delivering content on the gut-brain axis and the interaction between nutrition and behaviour.
Pedagogical Innovations and Contributions
Dr Hyland has played a pivotal role in integrating Problem-Based Learning (PBL) into the Graduate Entry to Medicine (GEM) programme, introducing interdisciplinary teaching methods that promote collaborative learning between students. He also led the GEM programme through its first Irish Medical Council accreditation. In his role as Chair of the School of Medicine Athena Swan Working Group, Dr Hyland fosters a culture of inclusivity and belonging, ensuring that the learning environment supports all students.
MINDinGUT Student Mobility Project
Dr Hyland co-led the international MINDinGUT student mobility project, an initiative that attracted over 65 participants from four continents. This project focused on interdisciplinary research and education in gut-brain axis biology, promoting cross-institutional collaboration and offering students hands-on experience in cutting-edge research across borders.
Past Teaching Commitments
Department of Pharmacology, UCC (2008-2018) During his tenure in the Department of Pharmacology at UCC, Dr Hyland held several significant teaching roles, including:
GM1003 – Fundamentals of Medicine III (Graduate Entry to Medicine)
Role: Module Coordinator
Dr Hyland coordinated and delivered lectures for this core module, focusing on the integration of pharmacology into clinical education for graduate-entry medical students.
PT3201 – Dental Pharmacology
Role: Module Coordinator (one academic year)
Dr Hyland developed and delivered a comprehensive pharmacology course tailored specifically for dental students.
PT3445 – Systems Pharmacology
Role: Lecturer
He lectured on systemic pharmacology, providing insights into the effects of drugs on body systems.
Small Group Learning (Case-Based Learning)
Dr Hyland coordinated and facilitated small group learning sessions for Graduate Entry to Medicine students, encouraging the application of theoretical knowledge to practical clinical cases.
University of Calgary (2004-2007)
At the University of Calgary, Dr Hyland taught courses such as:
MDSC 637.01 – Gastrointestinal Physiology
Role: Lecturer
Delivered advanced lectures on gastrointestinal physiology for graduate students, focusing on neurogastroenterology.
MDSC 619.02 – Systems Neuroscience II
Role: Lecturer
Provided in-depth lectures on systems neuroscience with an emphasis on the enteric nervous system.
Thesis Examination and Supervision
Dr Hyland has extensive experience as an external PhD examiner at various institutions, including:
Massey University, New Zealand
University of Melbourne, Australia
Queen Mary University of London, UK
University of Padova, Italy
University of Antwerp, Belgium
He has supervised multiple postgraduate research candidates, guiding their research in areas such as enteric neuroscience and gut-brain interactions.
CPD Contributions and Continuing Medical Education (CME)
Dr Hyland developed the CME course titled "The Gut Microbiome and Diet in Neurogastroenterology: A Guide for the Clinician", accredited by the European Accreditation Council for Continuing Medical Education. This course has provided clinicians with up-to-date knowledge on the gut microbiome and its role in gastrointestinal health. Additionally, he has been selected as Faculty to deliver the upcoming CME course, "Navigating Solutions for DGBI and GI Motility Disorders" at the Federation of Neurogastroenterology and Motility meeting.
Pharmacology Expert Group Curriculum Project
Dr Hyland contributed to the Core Undergraduate Pharmacology Curriculum Project led by the British Pharmacological Society, an expert group initiative aimed at developing a robust pharmacology curriculum for use in quality assurance and programme development. This curriculum has been successfully employed in institutions like Keele University and beyond, ensuring consistency and excellence in pharmacological education.
Additional Teaching Contributions
As Chair of the Graduate Studies Committee (GSC), Dr Hyland oversees the academic progress of postgraduate students, including 10 PhD and three MSc candidates. He is responsible for setting postgraduate teaching and training policies and organizes the annual Physiology Research Day, promoting student research and development. Dr Hyland also participates in mentoring undergraduate students through the SEFS first-year mentoring scheme, supporting their academic growth and career development.
Recent Postgraduates
| Graduation Year | Student Name | Institution | Degree Type | Thesis Title | |
|---|---|---|---|---|---|
| 2028 | Carla Viñola Renart | University College Cork | PHD | Gastrointestinal oxytocin in health and disease | |
| 2023 | Cecila Delprete | The University of Bologna | PHD | Pathogenetic mechanisms of gastrointestinal symptoms in a mouse model of Fabry disease: Insights on the microbiota-gut-brain axis | |
| 2020 | Jacinta Walsh | University College Cork | PHD | Gut microbiome-xenobiotic interactions: focus on drug metabolism | |
| 2019 | Jonathan Keane | University College Cork | PHD | The microbiota and colon cancer risk: cause or consequence? | |
| 2019 | Sarah O'Donovan | University College Cork | PHD | The microbiome-gut-brain axis in preclinical alpha-synuclein models of Parkinson's disease | |
| 2014 | Kevin Lomasney | University College Cork | PHD | The impact of host-microbe interactions on murine colonic secretomotor function | |
| 2012 | Siobhan Carroll | University College Cork | MSc | Physiological studies of gastrointestinal mast cells: Relevance to irritable bowel syndrome |
Research Information
Internal Collaborators
| Name | Institute | Country | |
|---|---|---|---|
| Prof. John Cryan | University College Cork | IRELAND | |
| Prof. Gerard Clarke | University College Cork | IRELAND | |
| Dr. Harriët Schellekens | University College Cork | IRELAND | |
| Dr. Aileen Houstan | University College Cork | IRELAND | |
| Prof. Cormac Gahan | University College Cork | IRELAND | |
| Dr Susan Joyce | University College Cork | IRELAND |
External Collaborators
| Name | Organisation / Institute | Country | |
|---|---|---|---|
| Dr Shalome Bassett | Fonterra, New Zealand | NEW ZEALAND | |
| Dr James Dekker | Fonterra, New Zealand | NEW ZEALAND | |
| Dr Elaine Patterson | Fonterra Microbiome Research Centre (Ireland) | IRELAND | |
| Prof. Marco Caprini | University of Bologna | ITALY | |
| Dr Alexander Boys | Dartmouth College | U.S.A. | |
| Prof. Roisin Owens | University of Cambridge | UNITED KINGDOM |
Contact details
-
Senior Lecturer - n.hyland@ucc.ie
- Western Gateway Building
University College Cork
Cork
Ireland - +353 21 420 5876
- research.ucc.ie/profiles/C008/N.Hyland@ucc.ie