Research Profile

Joseph O'Shea

Biography

Dr. Joey O'Shea is a Lecturer in Pharmaceutics in the School of Pharmacy, University College Cork. 
He completed his Bachelor of Pharmacy degree in UCC in 2012 and Master of Pharmacy degree in the Royal College of Surgeons in Ireland in 2013. Dr O'Shea completed his Ph.D. in the School of Pharmacy in UCC in 2018. The focus of his doctoral work was on the biopharmaceutical aspects of solid oral dose formulation performance and the predictive capacity of various in vitro, in vivo and in silico methods of characterisation for oral bio-enabling formulations. Following completion of his PhD, Dr O'Shea held numerous positions in the pharmaceutical industry in Ireland, including in formulation development, clinical and regulatory affairs and in process development and technical support. Dr O'Shea returned to academia in November 2019, taking up a role as Lecturer in Pharmaceutics in the School of Pharmacy, UCC. He currently teaches on the M.Pharm. undergraduate programme and on the MSc in Pharmaceutical Technology and Quality Systems, an on line masters course designed to train graduates working in the pharmaceutical industry to become a Qualified Person (QP). 

Publications

Peer Reviewed Journals

 YearPublication
(2019)'Food for thought: formulating away the food effect - a PEARRL review'
O'Shea JP;Holm R;O'Driscoll CM;Griffin BT; (2019) 'Food for thought: formulating away the food effect - a PEARRL review'. Journal of Pharmacy and Pharmacology, 71 (4)   [DOI] [Full Text] [Details]
(2019)'Toward the establishment of a standardized pre-clinical porcine model to predict food effects - case studies on Fenofibrate and Paracetamol'
Henze, Laura J.; Koehl, Niklas J.; O'Shea, Joseph P.; Holm, René; Vertzoni, Maria; Griffin, Brendan T. (2019) 'Toward the establishment of a standardized pre-clinical porcine model to predict food effects - case studies on Fenofibrate and Paracetamol'. International Journal Of Pharmaceutics: X,   [DOI] [Full Text] [Details]
(2019)'The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review'
Henze, Laura J.; Koehl, Niklas J.; O'Shea, Joseph P.; Kostewicz, Edmund S.; Holm, René; Griffin, Brendan T. (2019) 'The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review'. Journal of Pharmacy and Pharmacology, [Details]
(2017)'Mesoporous silica based dosage forms improve bioavailability of poorly soluble drugs in pigs: case example fenofibrate'
Joseph P. O’Shea, Kalpa Nagarsekar, Alena Wieber, Vanessa Witt3, Elisabeth Herbert, Caitriona M. O’Driscoll, Christoph Saal, Dieter Lubda, Brendan T. Griffin, Jennifer B. Dressman (2017) 'Mesoporous silica based dosage forms improve bioavailability of poorly soluble drugs in pigs: case example fenofibrate'. Journal of Pharmacy and Pharmacology,   [DOI] [Details]
(2017)'In vitro dissolutionmodels for the prediction of in vivo performance of an oral mesoporous silica formulation'
McCarthy, CA;Faisal, W;O'Shea, JP;Murphy, C;Ahern, RJ;Ryan, KB;Griffin, BT;Crean, AM (2017) 'In vitro dissolutionmodels for the prediction of in vivo performance of an oral mesoporous silica formulation'. Journal Of Controlled Release, 250 :86-95 [DOI] [Details]
(2016)'Folate-targeted amphiphilic cyclodextrin.siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged circulation in vivo'
Evans, J. C.,Malhotra, M.,Guo, J.,O'Shea, J. P.,Hanrahan, K.,O'Neill, A.,Landry, W. D.,Griffin, B. T.,Darcy, R.,Watson, R. W.,O'Driscoll, C. M. (2016) 'Folate-targeted amphiphilic cyclodextrin.siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged circulation in vivo'. Nanomedicine, 12 (8):2341-2351   [DOI] [Details]
(2015)'Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments'
O'Shea, JP;Faisal, W;Ruane-O'Hora, T;Devine, KJ;Kostewicz, ES;O'Driscoll, CM;Griffin, BT (2015) 'Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments'. European Journal Of Pharmaceutics And Biopharmaceutics, 96 :207-216 [DOI] [Details]

Professional Activities

Professional Associations

 AssociationFunctionFrom / To
Pharmaceutical Society of Ireland Member01-DEC-13 /

Contact details

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School of Pharmacy

Cógaisíocht

Cavanagh Pharmacy Building Room UG06 University College Cork

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